A5065019754- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Orthopaedic implants and arthroplasty
- Tuberculosis Research and Epidemiology
- Cancer therapeutics and mechanisms
- Natural product bioactivities and synthesis
- Bone and Dental Protein Studies
- Mycobacterium research and diagnosis
- Bioactive Compounds and Antitumor Agents
- Coccidia and coccidiosis research
- Lepidoptera: Biology and Taxonomy
- Phytochemistry and biological activities of Ficus species
- Synthesis and biological activity
- Biochemical and Structural Characterization
- Phytochemistry and Bioactive Compounds
- Endodontics and Root Canal Treatments
- Polymer Surface Interaction Studies
- Electrospun Nanofibers in Biomedical Applications
- Bioactive Natural Diterpenoids Research
- Antimicrobial Peptides and Activities
- Essential Oils and Antimicrobial Activity
- biodegradable polymer synthesis and properties
Soonchunhyang University
2010-2017
The candidacidal activity of histatin 5 is initiated through cell wall binding, followed by translocation and intracellular targeting, while the halocidin peptide exerts its attacking Candida membrane. To improve antimicrobial activities to understand killing mechanism two peptides, six hybrid peptides were designed conjugating halocidin. A comparative approach was established study activity, salt tolerance, glucan binding assay, cytotoxicity, generation ROS kinetics. CD spectrometry...
In this study, a new porous beta-tricalcium phosphate (β-TCP) granule was fabricated using the fibrous monolithic (FM) process and its in vitro biocompatibility vivo bone formation were evaluated. SEM micrograph images showed that MG-63 cells attached to surfaces of implant well proliferated. Cellular viability as high 75% 50% extract dilution solution. cDNA micro array analysis also carried out. analysis, we found total 12 up-regulated 25 down-regulated genes. Four rabbits used experiments....
Tuberculosis, one of the world's major health problems, has become more serious due to emergence multi-drug resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis (MTB). In this study, we performed three anti-MTB assays evaluate anti-mycobacterial activity naphthofuroquinone derivatives against MTB. Among them, methyl 5-[2-(dimethylamino)ethoxy]-7,12-dioxo-7,12-dihydrodinaphtho[1,2-b:2′,3′-d]furan-6-carboxylate (DFC2) exhibited strong MTB H37Ra, H37Rv four strains....