A5039713983- Heterotopic Ossification and Related Conditions
- Kruppel-like factors research
- Amyotrophic Lateral Sclerosis Research
- Renal Diseases and Glomerulopathies
- Cervical and Thoracic Myelopathy
- Medical Imaging and Pathology Studies
- Cancer-related molecular mechanisms research
- Hip disorders and treatments
- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Traditional Chinese Medicine Studies
- Chronic Kidney Disease and Diabetes
- Systemic Sclerosis and Related Diseases
- Spine and Intervertebral Disc Pathology
Changchun University of Chinese Medicine
2024
Affiliated Hospital of Qingdao University
2024
Qingdao University
2024
Shanghai Sixth People's Hospital
2022-2023
Shanghai Jiao Tong University
2022-2023
Shanghai Innovative Research Center of Traditional Chinese Medicine
2022-2023
Abstract Trauma‐induced heterotopic ossification (HO) is a complex disorder after musculoskeletal injury and characterized by aberrant extraskeletal bone formation. Recent studies shed light on critical role of dysregulated osteogenic differentiation in Krupel‐like factor 2 (KLF2) peroxisome proliferator‐activated receptor gamma (PPARγ) are master adapter proteins that link cellular responses to osteogenesis; however, their roles relationships HO remain elusive. Using murine burn/tenotomy...
Aims Heterotopic ossification (HO) is a common complication after elbow trauma and can cause severe upper limb disability. Although multiple prognostic factors have been reported to be associated with the development of post-traumatic HO, no model has yet able combine these predictors more succinctly convey information medical measures patients. Therefore, this study aimed identify leading formation HO surgery for trauma, establish validate nomogram predict probability in such particular...
Background: Heterotopic ossification (HO) is a common complication of elbow trauma that can affect limb mobility. Inflammation an initiating factor for HO formation. Tranexamic acid (TXA) reduce the inflammatory response after orthopaedic surgery. However, evidence regarding effectiveness TXA use prevention surgery lacking. Methods: This retrospective observational propensity-score-matched (PSM) cohort study was conducted from July 1, 2019, to June 30, 2021, at National Orthopedics Clinical...
Background IgA nephropathy (IgAN) is a significant contributor to chronic kidney disease (CKD). Renal arteriolar damage associated with IgAN prognosis. However, simple tools for predicting of remain limited. We aim develop and validate nomogram model renal in patients. Methods retrospectively analyzed 547 cases biopsy-proven Least absolute shrinkage selection operator (LASSO) regression logistic were applied screen factors patients IgAN. A was developed evaluate the The performance proposed...
Objective: Analysis of Traditional Chinese Medicine (TCM) constitution type general medical patients and the relationship between metabolic index. Methods: A cohort 1,029 individuals who underwent a physical examination at Affiliated Hospital Changchun University for identification their TCM January 2021 April 2023 were included in this study. Their data sorted analyzed using Microsoft Excel SPSS26.0 statistical software. Results: Among 1029 study participants, balanced (BC) was most...
Background: There are few methods for accurately assessing the risk of total hip arthroplasty (THA) in patients with osteoarthritis. A novel and reliable method that could play a substantial role research clinical routine should be investigated. The purpose present study was to develop deep-learning model can reliably predict THA use radiographic images symptom data. Methods: This retrospective, multicenter, case-control assessed joints on weighted-bearing anteroposterior pelvic radiographs...