A5100356746- Thyroid Disorders and Treatments
- Diabetes Treatment and Management
- Diabetes Management and Research
- Diabetes and associated disorders
- Liver Disease Diagnosis and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Hormonal Regulation and Hypertension
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Metabolism, Diabetes, and Cancer
- Cardiac Imaging and Diagnostics
- Glaucoma and retinal disorders
- PI3K/AKT/mTOR signaling in cancer
- Protein Kinase Regulation and GTPase Signaling
- Chronic Kidney Disease and Diabetes
- Pharmacological Effects of Natural Compounds
- Dialysis and Renal Disease Management
- Pain Mechanisms and Treatments
- Blood Pressure and Hypertension Studies
- High Altitude and Hypoxia
- Cardiovascular Function and Risk Factors
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Magnesium in Health and Disease
- Botulinum Toxin and Related Neurological Disorders
Affiliated Hospital of Hebei University
2024-2025
Guangzhou Medical University
2015-2025
Second Affiliated Hospital of Guangzhou Medical University
2015-2025
Affiliated Hospital of Qingdao University
2024
Qingdao University
2024
Tianjin Medical University General Hospital
2022
First Affiliated Hospital of Jiangxi Medical College
2022
Wenzhou City People's Hospital
2021
Peking University People's Hospital
2020
Peking University
2020
The risks and benefits of metformin use in patients with cirrhosis diabetes are debated. Although data on a protective effect against liver cancer development have been reported, is frequently discontinued once diagnosed because concerns about an increased risk adverse effects impairment. This study investigated whether continuation after diagnosis improves survival diabetes. Diabetic between 2000 2010 who were at the time identified (n = 250). Data retrospectively abstracted from medical...
Growing evidence suggests that pretransplant alpha‐fetoprotein (AFP) predicts outcomes of hepatocellular carcinoma (HCC) patients treated with liver transplantation. We aimed to determine whether AFP, Lens culinaris agglutinin‐reactive (AFP‐L3), and des‐gamma‐carboxyprothrombin (DCP) predicted HCC recurrence after A retrospective cohort study 313 undergoing transplantation between 2000 2008 was conducted, 48 (15.3%) developed during a median follow‐up 90.8 months. The 127 available serum...
The aim of this study was to investigate the impact diabetes on mortality and adverse outcomes in COVID-19 patients analyse associated risk factors. This is a retrospective cohort 500 hospitalized with infection (214 286 without diabetes) admitted tertiary hospital China from December 2022 February 2023. Demographic information, clinical characteristics were collected. Survival status investigated at discharge 6 months after discharge. rate higher than non-diabetic patients, both discharge,...
Objective: To evaluate the effectiveness of deep learning technology based on generative adversarial networks (GANs) in reducing motion artifacts cardiac magnetic resonance (CMR) cine sequences. Methods: The training and testing datasets consisted 2000 200 pairs clear blurry images, respectively, acquired through simulated CMR These were used to establish train a GAN model. assess efficacy network mitigating artifacts, 100 images with 37 real-world encountered clinical practice selected....
Diabetes mellitus (DM) and thyroid dysfunction (TD) are two closely associated disorders. The objective of the present study was to investigate status relationships between hormones, diabetic complications metabolic parameters in hospitalized patients with newly diagnosed type 2 DM (T2DM). This an observational cross-sectional study, conducting on 340 T2DM who were admitted ward endocrinology department 120 matched individuals without diabetes. Anthropometric, clinical biochemical data...
PDIhypomagnesemia.A higher frequency of
Abstract Background The prevalence of hypertensive heart disease (HHD) is high and there currently no easy way to detect early HHD. Explore the application radiomics using cardiac magnetic resonance (CMR) non-enhanced cine sequences in diagnosing HHD latent changes caused by hypertension. Methods 132 patients who underwent CMR scanning were divided into groups: (42), hypertension with normal structure function (HWN) group (46), control (NOR) (44). Myocardial regions end-diastolic (ED)...
Whether cortisol secretion is linked with microalbuminuria remains undefined.We aimed to investigate the relationship between serum levels and presence of in patients type 2 diabetes (T2DM) prediabetes.A cross-sectional study was conducted 211 T2DM or prediabetes.Serum measured at 8:00 h, 16:00 0:00 h.The level circadian rhythm ACTH were also evaluated.Urine excretion albumin measured.Patients subdivided into (MAU) group (n= 120) normoalbuminuria (NAU) (n = 91) according status...
Mitochondrial dysfunction-induced apoptosis plays a crucial role in the progression of diabetic cardiomyopathy (DCM). Sestrin2 is an important oxidative stress response protein and involved maintenance mitochondrial function, especially under stress. The aim present study was to investigate DCM explore underlying mechanisms. H9c2 cardiomyocytes were induced with high glucose (HG) medium (33 mmol/l glucose) for vitro model. C57BL/6 mice vivo model by intraperitoneal streptozotocin injection....
Diabetic cardiomyopathy increases the risk of heart failure and is one major causes death in patients with diabetes. The present study investigated expression function tumor necrosis factor receptor‑associated protein 1 (TRAP1) cardiomyocytes a hyperglycemic state. For vitro study, H9c2 cells (rat cardiomyoblasts) were treated normal glucose, high glucose. TRAP1 was determined by reverse transcription‑quantitative PCR western blot analysis. Viability detected using CellTiter 96® AQueous One...
As one of the most challenging complications in management diabetes mellitus, painful diabetic peripheral neuropathy (PDPN) is accompanied by various clinical manifestations, including numbness, burning, coldness, and other sensory abnormalities extremities. Meanwhile, PDPN seriously affects life quality patients causes great pain. Western medicine mostly provides symptomatic treatments, such as antioxidants, aldose reductase inhibitors, nerve nutrition, microcirculation improvement,...
Patient-centered care is respectful to a patient's preference. All prior clinical trials on patient self-titration algorithms for basal insulin were decided by physicians. We hypothesized that patients and physicians have different preferences.Physicians diabetes asked choose their preferred glargine algorithm among 5 algorithms. Algorithm 1, 1 U increase once daily; 2, 2 every 3 days; 3, 4, titration days according fasting blood glucose, 5, weekly 2-8 based 3-day mean glucose levels.Eleven...
Introduction Subcutaneous administration of insulin is the preferred method for achieving glucose control in non-critically ill patients with diabetes. Glucose-based titration protocols were widely applied clinical practice. However, most these algorithms are experience-based and there considerable variability complexity. This study aimed to compare effectiveness safety a weight-based algorithm versus glucose-based hospitalized type 2 diabetes mellitus (T2DM). Research design methods...
Background IgA nephropathy (IgAN) is a significant contributor to chronic kidney disease (CKD). Renal arteriolar damage associated with IgAN prognosis. However, simple tools for predicting of remain limited. We aim develop and validate nomogram model renal in patients. Methods retrospectively analyzed 547 cases biopsy-proven Least absolute shrinkage selection operator (LASSO) regression logistic were applied screen factors patients IgAN. A was developed evaluate the The performance proposed...
Aim: Insulin titration often faces inertia, hindering glycemic control. A patient-centered approach empowers patients to overcome this inertia. This study aims compare the effectiveness of patient-preferred and guideline-recommended self-titration algorithms in achieving targets improving adherence. Methods: Outpatients with type 2 diabetes (T2D) who did not respond oral antihyperglycemic drugs (OAD) were assessed. They randomly assigned groups. In group, individuals selected an algorithm...