A5102018934- Diabetes and associated disorders
- Pancreatic function and diabetes
- Diabetes Management and Research
- Esophageal Cancer Research and Treatment
- Celiac Disease Research and Management
- Monoclonal and Polyclonal Antibodies Research
- Diabetes Treatment and Management
- Nasal Surgery and Airway Studies
- Syphilis Diagnosis and Treatment
- Ear Surgery and Otitis Media
- Diabetic Foot Ulcer Assessment and Management
- HIV, Drug Use, Sexual Risk
- Cerebrovascular and Carotid Artery Diseases
- Electrochemical sensors and biosensors
- Pediatric health and respiratory diseases
- Cardiovascular Disease and Adiposity
- Lung Cancer Treatments and Mutations
- Microscopic Colitis
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 and COVID-19 Research
- Advanced Biosensing Techniques and Applications
- Otitis Media and Relapsing Polychondritis
- Allergic Rhinitis and Sensitization
- HIV/AIDS Research and Interventions
- Ear and Head Tumors
Hunan Normal University
2024
Hunan Provincial People's Hospital
2024
Zhejiang Center for Disease Control and Prevention
2023-2024
South China University of Technology
2018-2022
Guangzhou First People's Hospital
2010-2022
Guangzhou Medical University
2010-2022
University of Colorado Denver
2020-2022
University of Colorado Anschutz Medical Campus
2021
People's Hospital of Yangzhong
1990
Objective: As diabetes is a risk factor for severe symptoms, hospitalization, and death with COVID-19 disease, we aimed to assess the prevalence of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in children adults without type 1 Colorado during 2020. Research Design Methods: We developed highly sensitive specific test against SARS-CoV-2 measured new-onset (n = 129) established 94) seen routine care at our center between January October The were also 562 102 from general...
Broncho-vaxom alleviates persistent allergic rhinitis in patients by
Objective: Large-scale screening of the general population for islet autoantibodies (IAbs) to detect type 1 diabetes (T1D) has started worldwide. The standard method separate radio-binding assay (RBA) each IAb is an inefficient bottleneck. Furthermore, most positive results by RBA in individuals without a clinical diagnosis T1D are low-affinity and not predictive future diabetes. Research Design Methods: We have developed validated novel 6-Plex based on electrochemiluminescence (ECL)...
Single ZnT8 autoantibody (ZnT8A) positivity by standard radiobinding assay (RBA) is commonly seen in nondiabetes population-based screening and the risk of progression to type 1 diabetes (T1D) subjects with single ZnT8A unknown. Identify T1D individuals positive only for ZnT8A. We developed an electrochemiluminescence (ECL) detect high-affinity validated it 3 populations: 302 patients newly diagnosed T1D, 135 nondiabetic children RBA among 23 400 screened Autoimmunity Screening Kids (ASK)...
Patient-centered care is respectful to a patient's preference. All prior clinical trials on patient self-titration algorithms for basal insulin were decided by physicians. We hypothesized that patients and physicians have different preferences.Physicians diabetes asked choose their preferred glargine algorithm among 5 algorithms. Algorithm 1, 1 U increase once daily; 2, 2 every 3 days; 3, 4, titration days according fasting blood glucose, 5, weekly 2-8 based 3-day mean glucose levels.Eleven...
Autoimmunity Screening for Kids (ASK) study was launched to screen general population children type 1 diabetes (T1D) and celiac disease (CD). A total of 23,319 from were screened. high throughput multiplex electrochemiluminescence (ECL) assay multiautoantibodies in a single well applied, parallel with standard radiobinding (RBA). All any positive autoantibodies screening revisited within one month confirmation followed every 6 months. Among children, 2.6% (606/23,319) tested TGA. Multiplex...
To study the difference of postoperative efficacy between two-person three-hand ear endoscopy and microscopic tympanoplasty in patients with chronic suppurative otitis media, to explore advantages disadvantages endoscopy.
To investigate syphilis infection and related factors among HIV-infected patients being followed up for more than one year in Zhejiang Province.
Islet autoantibodies (IAbs) are widely used in type 1 diabetes (T1D) diagnosis and prediction. Four major IAbs to insulin (IAA), glutamate decarboxylase-65 (GADA), insulinoma antigen-2 (IA-2A), zinc transporter-8 (ZnT8A) equally important disease Presently, up 40% of patients diagnosed with T1D go on develop other autoimmune disorders. Unfortunately, current screening methods using a single autoantibody for measurement laborious inefficient large scale studies. We recently developed simple...
Objective: To investigate the prevalence of syphilis in HIV-infected patients with transmission risk and influencing factors Zhejiang Province. Method: The information about patients, who were alive, had been diagnosed HIV for >1 year, received no antiviral treatment or viral load ≥50 copies/ml, aged ≥15 years, reported as December 31, 2018 collected from China Information System Disease Control Prevention. included general demographic characteristics, sexual behavior characteristics...
Objective: To understand the related factors on previous HIV testing behavior among MSM who visit gay bathroom in Hangzhou, Zhejiang province. Methods: Through time-location sampling (TLS) survey, men had oral sex or anal with past 6 months were interviewed Hangzhou from October 2015 to January 2016. Software SPSS 22.0 was used analyze acceptance, sexual behaviors and condom usage of during months, χ(2) test logistic regression model for univariate multivariate analyses. Results: Our study...
An ongoing clinical trial, Autoimmunity Screening for Kids (ASK), is the first screening study in general population type 1 diabetes (T1D) and celiac disease United States. With coronavirus 2019 (COVID-19) pandemic, epidemiology of COVID-19 knowledge about association between infection T1D development are urgently needed. The currently standard method radio-binding assay (RBA) has met two great challenges: low efficiency with a single format specificity large proportion low-affinity...
Objective:To report surgical techniques, outcomes, clinical experience and application key point of transcanal endoscopic ear surgery for tympanosclerosis. Method: Data from 25 patients (13 males 12 females; aged 27-61 years, mean=48.8 years) who underwent tympanosclerosis in our department January 2016 to June 2017 were retrospectively analyzed. Removal tympanoplasty individualized. Patients followed up at postoperative 1, 3 6 month. Result: There no failure tympanal reconstruction by...
Background: The incidence of type 1 diabetes mellitus (T1DM), especially in children, has rapidly increased China. However, the prevalence adult-onset classic T1DM and latent autoimmune adults (LADA) remains unknown.