A5048772214- Synthesis and biological activity
- Natural Compound Pharmacology Studies
- Liquid Crystal Research Advancements
- Biodiesel Production and Applications
- Phytochemistry and Biological Activities
- Computational Drug Discovery Methods
- Click Chemistry and Applications
- Synthesis and Biological Evaluation
- Natural product bioactivities and synthesis
- Biological Activity of Diterpenoids and Biflavonoids
- Enzyme Catalysis and Immobilization
- Catalysis and Hydrodesulfurization Studies
- Bioactive Compounds and Antitumor Agents
- Flame retardant materials and properties
- Cholinesterase and Neurodegenerative Diseases
- X-ray Diffraction in Crystallography
- Curcumin's Biomedical Applications
- Crystallization and Solubility Studies
- Coconut Research and Applications
- Bioactive natural compounds
- Surfactants and Colloidal Systems
- Synthesis and Characterization of Heterocyclic Compounds
- Natural Antidiabetic Agents Studies
- Photochemistry and Electron Transfer Studies
- Multicomponent Synthesis of Heterocycles
Universiti Sains Malaysia
2016-2025
Hospital Universiti Sains Malaysia
2019-2022
Kent State University
2008-2021
This paper presents a novel electrochemical sensor based on pencil graphite electrode (PGE) modified with molecularly imprinted graphene oxide/zinc oxide nanocomposites for sensitive detection of andrographolide. is the first report method electroanalytical determination andrographolide through PGE. The PGE was successfully fabricated and characterized. Then, quantitative analyses were performed by cyclic voltammetry (CV) differential pulse (DPV). optimum conditions this analysis supporting...
A search for anticancer agents has prompted the design and synthesis of new chalcone, pyrazoline pyrimidine derivatives as potential epidermal growth factor receptor (EGFR) kinase inhibitors. These derivatives' binding affinities were predicted by AutoDock, which showed that EGFR-kinase inhibitors have good energies, ranging from −10.91 to −7.32 kcal/mol. compounds synthesized characterized using elemental analysis (CHN analysis) spectroscopic techniques (FTIR NMR). Among derivatives, 4Aiii...
Context: Garcinia hombroniana Pierre, known as manggis hutan in Malaysia is a rich source of xanthones and benzophenones.Objectives: This study was aimed to isolate characterize potential cholinesterase inhibitors from the extracts G. bark investigate their interactions with enzymes.Materials methods: The dichloromethane extract afforded five triterpenoids which were characterized by NMR mass spectral techniques. Cholinesterase inhibitory assay molecular docking performed get insight...
Malaria is a protozoan disease caused by unicellular parasite named Plasmodium (Phylum- Apicomplexa). World Health Organization has estimated roughly fifty percent of the world's community lives under continuing threat malaria. The focus drug discovery increased towards valuable structures known as chalcones, pyrazoline, and pyrimidine due to their extensive bioactivity in malaria treatment. In this study, four chalcone derivatives (1–4) have been synthesized via Claisen-Schmidt...
A structural study of epoxidized natural rubber (ENR-50) and its cyclic dithiocarbonate derivative was carried out using NMR spectroscopy techniques. The overlapping 1H-NMR signals ENR-50 at δ 1.56, 1.68–1.70, 2.06, 2.15–2.17 ppm were successfully assigned. In this work, the 13C-NMR chemical shift assignments consistent to previously reported work. synthesized from reaction purified with carbon disulfide (CS2), in presence 4-dimethylaminopyridine (DMAP) as catalyst reflux temperature....
The genus Garcinia is reported to possess antimicrobial, anti‐inflammatory, anticancer, hepatoprotective and anti‐HIV activities. hombroniana in Malaysia used treat itching as a protective medicine after child birth. This study was aimed isolate the chemical constituents from bark of G . explore their possible pharmacological potential. Ethyl acetate extract afforded one new (1) six (2–7) known 3 → 8 rotameric biflavonoids. Their structures were elucidated by UV, IR NMR (1D 2D) spectroscopy...
A series of new hexasubstituted cyclotriphosphazene compounds (4a–j) consisting two Schiff base linking units and different terminal substituents was successfully synthesized characterized. The structures these were confirmed using Fourier Transform Infra-Red (FTIR), Nuclear Magnetic Resonance (NMR), CHN elemental analysis. Polarized optical microscopy (POM) used to determine their liquid-crystal behavior, which then further differential scanning calorimetry (DSC). Compounds 4a–i with...