A5055787641- Carcinogens and Genotoxicity Assessment
- Heavy Metal Exposure and Toxicity
- Arsenic contamination and mitigation
- Animal testing and alternatives
- Air Quality and Health Impacts
- Effects and risks of endocrine disrupting chemicals
- Selenium in Biological Systems
- Sperm and Testicular Function
- Orthopedic Infections and Treatments
- Electrophoretic Deposition in Materials Science
- TiO2 Photocatalysis and Solar Cells
- Peatlands and Wetlands Ecology
- Hydrology and Watershed Management Studies
- Connective tissue disorders research
- Vibrio bacteria research studies
- Forest Management and Policy
- Orthopaedic implants and arthroplasty
- Cleft Lip and Palate Research
- Sepsis Diagnosis and Treatment
- Plant Water Relations and Carbon Dynamics
- Psidium guajava Extracts and Applications
- Urban Heat Island Mitigation
- Antioxidant Activity and Oxidative Stress
- Environmental Justice and Health Disparities
- Essential Oils and Antimicrobial Activity
Universidad Autónoma de Coahuila
2013-2024
Universidad Autónoma de Nuevo León
2015
An emerging concern is the influences of early life exposure to environmental toxicants on offspring characteristics in later life. Since recent evidence suggests a transgenerational transference aberrant phenotypes from exposed-parents non-exposed related adult-onset diseases including reproductive phenotype. The potential arsenic well know genotoxic and epigenetic modifier agent has not been assessed mammals until now. In this experimental study, we evaluated effects rat model with chronic...
The micronucleus (MN) assay evaluates the effects of low doses genotoxic carcinogens and can detect structural lesions that survive mitotic cycles.The objective this study was to determine both genotoxicity nickel (Ni) in buccal epithelial cells urinary excretion Ni children with metal crowns.This a prospective longitudinal based on 37 patients selected at Facultad de Odontología la Universidad Autónoma Coahuila.MN assays were performed using from patients, levels determined urine samples...
Abstract Differentiated cells telomere length is an indicator of senescence or lifespan; however, in peripheral blood leukocytes the relative shortening has been considered as a biological marker aging, and lengthening associated risk to cancer. Individual’s age, type tissue, lifestyle, environmental factors make variable. The presence carcinogens such arsenic (As) influence causal agents these alterations, main modes action for As described are oxidative stress, reduction DNA repair...
At present, the use of nanoparticles is a controversial topic, especially when analyzing their effects in human tissues. Nanoparticles (NPs) can cause oxidative stress by increasing membrane lipids peroxidation and reactive oxygen species, decreasing intracellular glutathione. Oxidative plays an important role cell signaling inflammatory responses. It result genotoxicity, affect proliferation, induce DNA damage. The objective this study to evaluate genotoxic potential NPs lymphocyte DNA....
Different studies have suggested an association between arsenic (As) exposure and damage to single-stranded DNA by reactive oxygen species derived from the biotransformation of arsenic. The single strand damages are converted double upon interaction with ultraviolet radiation. Analysis genomic integrity is important for assessing genotoxicity caused environmental pollutants. In this study, we compared concentration As in drinking water, nutritional status, lifestyle variables, level exposed...
Multiple comorbidities related to arsenic exposure through drinking water continue be public problems worldwide, principally in chronically exposed populations, such as those the Comarca Lagunera (CL), Mexico. In addition, this relationship could exacerbated by an early life placenta and later breast milk. This study conducted a comparative analysis of levels multiple biological samples from pregnant women their neonates CL comparison region, Saltillo. Total placenta, milk, blood, urine were...
Formaldehyde (FA) is an environmental xenobiotic, which genotoxic and carcinogenic to humans animals; it induces DNA damage, mutations, clastogenicity during critical cytogenetic events.FA-mediated oxidative stress important mechanism that has been associated with the induction of cytotoxic damage.Therefore, objective this study was evaluate dispersion sperm chromatin reproductive parameters induced by exposure 10817 Sperm formaldehyde in Wistar rats ©FUNPEC-RP www.funpecrp.com.brGenetics...
For the EPD, different voltages and times were used. Male rats used in four groups (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle="italic">3</mml:mn></mml:math>) with treatments. The blood sample was obtained for genotoxic analysis liver kidney organs removed histopathological analysis. amount of NPs TiO 2 deposited on samples arches increases gradually 15 30 s. At all voltages, however, at 45, 60, 75, 90 s, there is an...
Precision-cut tissue slices are considered an organotypic 3D model widely used in biomedical research. The comet assay is important screening test for early genotoxicity risk assessment that mainly applied on vitro models. aim of the present study was to provide a organ system determination using modified method since stromal components from original make this technique complicated.A validated precision-cut hamster kidney analyze antigenotoxic effect phenolic compounds caffeic acid,...
Estudios recientes han demostrado que los compuestos activos presentes en extractos de C. chayamansa, E. prostrata y J. dioica tienen propiedades antioxidantes. Los resultados obtenidos nuestro estudio fueron fenólicos solubles mostraron chayamansa 6,34, 10,67, 1,83 mg equiv ácido gálico/gm BS respectivamente. antioxidantes agua por el método ABTS para 5.9, 12.7 2.5 mM equiv. trolox/gr BS. histopatológicos muestran una mejorÃa tejidos tratados con después la inducción a hiperglicemia.
Amoebiasis is a parasitic disease that causes thousands of deaths every year, its adverse effects and resistance to conventional treatments have led the search new treatment options, as well development novel screening methods. In this work, we implemented 3D model intestine liver slices from hamsters were infected ex vivo with virulent E. histolytica trophozoites. Results show preserved histology in both uninfected tissues ulcerations, destruction epithelial cells, inflammatory reaction...
The aim of this study was to analyze the reliability agreement between surgeons when using Parkland Grading Scale for Acute Cholecystitis (PGS-AC).
Formaldehyde (FA) is an oxidative stress inducer and a known carcinogen. Hedeoma drummondii has been shown to have potential as chemopreventive agent. The aim of this study was assess the protective effect H. on FA-induced genotoxic damage, sperm quality parameters, histological changes testis. male Wistar rats used were divided into following groups: (G1) 100 mg/kg drummondii; (G2) 10 FA; (G3) + (G4) phosphate-buffered saline; (G5) α-tocopherol; (G6) α-tocopherol (G7) soybean oil. results...
El Theracal TM LC es un cemento silicato de calcio (Ca) modificado con resina (SMCR) que ha demostrado ser material ideal para el tratamiento dentino-pulpar por su alta tasa formación calcio. Los biomateriales contenido Ca tienden a tener aumento en biodisponibilidad, estimulando la del puente dentario atreves las células involucradas tejidos mineralizados, promoviendo diferenciación fibroblastos odontoblastos y aumentando actividad enzima pirofostasa responsable mineralización dentina....
The purpose of this study was to evaluate by morphological methods, if a mixture Fibroquel® and hyaluronic acid implanted in an animal model cranial bone injury could promote regeneration. 12 Wistar rats were divided three groups, control group, without treatment with treatment. After experimental period, samples taken stained H & E, Masson trichrome, PAS-D, immunohistochemistry anti-PCNA monoclonal antibody applied semiquantitative morphometric method. Treatment group showed extensive...
The present study aimed to evaluate, in vitro, the cestocidal effect of Pyrantel-Oxantel on Dipylidium caninum tapeworm. Each intestine sample was obtained by means a transversal incision abdominal area each euthanized canine subject, individually dissected via longitudinal incision, and examined for presence D. caninum. An optical microscope used identify verify proglottid morphology viability based its macroscopic appearance. effects (75 mg pyrantel pamoate; 75 oxantel pamoate) were...