- Forensic Toxicology and Drug Analysis
- Peroxisome Proliferator-Activated Receptors
- Essential Oils and Antimicrobial Activity
- Plant chemical constituents analysis
- Cancer Cells and Metastasis
- Stroke Rehabilitation and Recovery
- Psidium guajava Extracts and Applications
- Phytochemical Studies and Bioactivities
- Plant-based Medicinal Research
- Molecular Biology Techniques and Applications
- Poisoning and overdose treatments
- Drug-Induced Hepatotoxicity and Protection
- Transgenic Plants and Applications
- Animal Ecology and Behavior Studies
- Estrogen and related hormone effects
- Carcinogens and Genotoxicity Assessment
- vaccines and immunoinformatics approaches
- Birth, Development, and Health
- Nephrotoxicity and Medicinal Plants
- Geography and Education Methods
- Advanced Glycation End Products research
- Cancer and biochemical research
- Connective tissue disorders research
- Animal testing and alternatives
- Retinoids in leukemia and cellular processes
Lund University
2024
Universidad Autónoma de Coahuila
2017-2023
Universidad Autónoma de La Laguna
2020-2022
Agencia de Evaluación de Tecnologías Sanitarias
2019
Universidad Autónoma de Nuevo León
2011-2013
Abstract BACKGROUND The poorly vascularized, peri-necrotic GBM niche drives a metabolic switch towards adaptive lipid metabolism. Failure to adapt results in profound areas of necrosis, hallmark associated with worse outcome. Surprisingly few studies have addressed whether necrotic debris represents passive terminus or could actively contribute progression. Peri-necrotic regions are enriched intracellular droplets (LDs), as shown by us and others, highly infiltrated macrophages. Here, we...
At present, the use of nanoparticles is a controversial topic, especially when analyzing their effects in human tissues. Nanoparticles (NPs) can cause oxidative stress by increasing membrane lipids peroxidation and reactive oxygen species, decreasing intracellular glutathione. Oxidative plays an important role cell signaling inflammatory responses. It result genotoxicity, affect proliferation, induce DNA damage. The objective this study to evaluate genotoxic potential NPs lymphocyte DNA....
To determine the effects of autologous leukocyte-poor platelet-rich plasma (LP-PRP) on expression markers involved in cartilage-extracellular matrix production and inflammation cartilage explants bearing osteoarthritis.Cartilage LP-PRP were obtained from 10 patients who underwent total knee arthroplasty. The cultured spinner flasks for 28 days presence interleukin (IL)-1β and/or LP-PRP. gene catabolic (MMP13, ADAMTS5, IL1β) anabolic factors (COL2A1, ACAN, SOX9) was quantified. A histological...
El Extracto Acuoso de Orégano
Background: The world's population is still growing, having an impact on the environment and economic growth of developing countries; so that, there a particular interest in development new fertility control methods, focused male contraception. Objective: objective this study was to evaluate effect methanolic extracts leaf fruit Azadirachta indica sperm quality testicular histology Long Evans rats. Methods: Antifertility effects A. 24 rats were investigated. animals randomly divided into two...
For the EPD, different voltages and times were used. Male rats used in four groups (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle="italic">3</mml:mn></mml:math>) with treatments. The blood sample was obtained for genotoxic analysis liver kidney organs removed histopathological analysis. amount of NPs TiO 2 deposited on samples arches increases gradually 15 30 s. At all voltages, however, at 45, 60, 75, 90 s, there is an...
RESUMEN: Karwinskia humboldtiana (Kh) es un arbusto venenoso responsable de numerosos casos intoxicación accidental en humanos.En la literatura se ha descrito a crónica con Kh como uno polineuropatía sin describir si existen o no alteraciones órganos distintos al SNC y SNP lo el riñón.El objetivo este estudio fue evaluar morfología renal modelo Kh.Se utilizaron 32 ratas Wistar, dividieron cuatro grupos (n=8) donde 5 cada grupo fueron intoxicadas 3 control intoxicadas.A las les administraron...
Abstract All‐trans retinoic acid (ATRA) has been extensively studied as an integrating component of endocrine functions in the pancreas. The aim this study was to evaluate effects ATRA on physiopathological biomarkers experimental model rat with type 1 diabetes induced by alloxan (T1D). Twenty Wistar rats were divided equally into five groups, each receiving a different treatment: control group (CG), diabetic without T1D treatment, treated ATRA, supplemented vitamin E (VIT E), and that given...
The tissue microarrays (TMAs) were first called multitumor block.In 1998 was described the current technique, that uses an innovated sampling method for more than 1,000 cylindrical paraffin core biopsies in a single block.TMAs are now considered as useful powerful research tool Histology and Pathology laboratories, standardization of immunohistochemical techniques along with situ hybridization.However, one disadvantage to its widespread use is high cost professional punches, complexity...
RESUMEN: La técnica convencional (TC) que usa alcohol como agente deshidratante,
RESUMEN:Petiveria alliacea, es conocida con diferentes nombres según el lugar donde se le encuentre.Estudios hojas, tallo, raíz o extractos describen múltiples usos medicinales.Sin embargo, son pocos los que efectos tóxicos.En este estudio evaluó efecto morfológico de vapores la P. alliacea sobre tracto respiratorio ratas Wistar.Se emplearon 15 divididas en 5 grupos (n=3): control absoluto, 0, 5, y 30 minutos post-exposición (grupos I-V, respectivamente).Las sacrificaron colectaron muestras...
producir efectos adversos.A la fecha no existe evidencia que ratifique R. graveolens
Estudios recientes han demostrado que los compuestos activos presentes en extractos de C. chayamansa, E. prostrata y J. dioica tienen propiedades antioxidantes. Los resultados obtenidos nuestro estudio fueron fenólicos solubles mostraron chayamansa 6,34, 10,67, 1,83 mg equiv ácido gálico/gm BS respectivamente. antioxidantes agua por el método ABTS para 5.9, 12.7 2.5 mM equiv. trolox/gr BS. histopatológicos muestran una mejorÃa tejidos tratados con después la inducción a hiperglicemia.
Immunization or vaccination is the process of inducing artificial immunity against an antigen taking advantage mechanisms immunological memory. Current vaccines include substances known as adjuvants, which tend to improve immunogenicity antigen, reduce quantity employed, and boost immune response in weak responders. Unfortunately, only a few vaccine adjuvants are approved for human use.Thus, objective this study was investigate effect Tannic acid on humoral cell-mediated bovine serum albumin...
RESUMEN:Ruta graveolens es una planta nativa del Mediterráneo Oriental y área Sur Occidental de Asia, esta se han aislado más 120 compuestos químicos.En un estudio previo en nuestro laboratorio observó que extracto acuoso R. causó necrosis alteraciones morfológicas sugestivas apoptosis sobre el hígado rata Wistar.El objetivo presente estudio, fue evaluar la inducción posible efecto antiproliferativo in vivo acuso norte México, mediante métodos inmunohistoquímicos.Se utilizaron 25 ratas...
Routine preparation of paraffin embedded tissue for histopathological diagnosis, here termed conventional histological technique (CT), whether performed manually or using an automated system, requires approximately 12 h. We developed earlier a rapid acetone dehydration (AT) processing biopsies nervous that meets requirements preserving morphology and staining properties, reduces time to 3.3 compared the properties human organ including adrenal gland, liver, ovary, pancreas, prostate, testis...
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