A5081747918- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Helicobacter pylori-related gastroenterology studies
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- COVID-19 Clinical Research Studies
- Esophageal Cancer Research and Treatment
- Artificial Intelligence in Healthcare
- Liver Diseases and Immunity
- SARS-CoV-2 and COVID-19 Research
- Inflammatory Bowel Disease
- COVID-19 diagnosis using AI
- Pancreatic and Hepatic Oncology Research
- Cancer Research and Treatments
- Kruppel-like factors research
- Trace Elements in Health
- COVID-19 Impact on Reproduction
- Gastrointestinal motility and disorders
- Dietary Effects on Health
- Pharmacological Effects and Toxicity Studies
- Heavy Metal Exposure and Toxicity
- Retinoids in leukemia and cellular processes
- Clostridium difficile and Clostridium perfringens research
- Curcumin's Biomedical Applications
- Machine Learning in Healthcare
Johnson University
2017-2024
Rutgers, The State University of New Jersey
2017-2024
University of Nevada, Las Vegas
2023
Rutgers Sexual and Reproductive Health and Rights
2020-2023
Nonalcoholic fatty liver disease (NAFLD) is associated with obesity and increased risk of cancer. The impacts bariatric surgery on cancer in NAFLD patients are unknown. We investigated the effect severe using MarketScan database.We conducted a retrospective cohort study 18 to 64 years old newly diagnosed between 2007 2017. used Cox proportional hazard models examine association surgery, modeled as time-varying covariate, risks any obesity-related cancer, while accounting for confounding...
Importance There are no approved treatments for nonalcoholic fatty liver disease (NAFLD) despite its association with obesity and increased risk of cardiovascular (CVD). Objective To examine the between bariatric surgery CVD in individuals severe NAFLD. Design, Setting, Participants This large, population-based retrospective cohort study obtained data from MarketScan Commercial Claims Encounters database January 1, 2007, to December 31, 2017. included insured adults aged 18 64 years NAFLD...
Abstract People with acute COVID-19 due to SARS-CoV-2 infection experience a range of symptoms, but major factors contributing severe clinical outcomes remain be understood. Emerging evidence suggests associations between the gut microbiome and severity progression COVID-19. To better understand host-microbiota interactions in COVID-19, we characterized intestinal patients active comparison recovered uninfected healthy controls. We performed 16S rRNA sequencing stool samples collected May...
Gastroesophageal reflux disease (GERD) clinically predisposes to columnar Barrett's metaplasia (BM) in the distal esophagus. We demonstrate evidence supporting cellular origin of BM from reprograming or transcommitment resident normal esophageal squamous (NES) epithelial cells response acid and bile (A + B) exposure using an vitro cell culture model. The hTERT-immortalized NES line NES-B10T was exposed 5 min/day A B mixture for 30 wk. Morphological changes, mRNA, protein expression levels...
Cirrhosis is associated with an increased risk of acute kidney injury (AKI) and hepatorenal syndrome (HRS). Healthcare utilization cost burden AKI HRS in cirrhosis unknown. We aimed to analyze the health care use patients United States by using real-world claims data.We conducted a case-control study Truven Health MarketScan Commercial Claims databases from 2007-2017. A total 34,398 or without 4,364 were identified International Classification Diseases, Ninth Tenth Revision, codes matched...
Non-Alcoholic Fatty Liver Disease (NAFLD) is becoming increasingly prevalent in the world population. Without diagnosis at right time, NAFLD can lead to non-alcoholic steatohepatitis (NASH) and subsequent liver damage. The treatment of depend on activity score (NAS) fibrosis stage, which are usually evaluated from biopsies by pathologists. In this work, we propose a novel method automatically predict NAS stage CT data that non-invasive inexpensive obtain compared with biopsy. We also present...
MicroRNAs (miRNAs) are important post-translational regulators. Elevated levels of miR-206 in ulcerative colitis (UC) were associated with suppression anti-inflammatory A3 adenosine receptor (A3AR) expression. However, the relationship to histologic remission UC patients remains unknown. This study correlates expression treated via long-term mesalamine treatment identify a possible mode action for this mainstay drug UC.Expression and its target A3AR analyzed HT29 cell line before after (2...
Background Rifaximin and/or lactulose therapy is widely used in cirrhotic patients for the prevention and treatment of hepatic encephalopathy. The incidence gastrointestinal cancers these on lactulose, rifaximin, combination unknown. We investigated possible effect rifaximin cancer risk with cirrhosis using MarketScan database. Methods A retrospective cohort study was conducted Truven Health Commercial Claims databases from 2007-2017. An index date defined each participant as earliest...
Non-alcoholic fatty liver disease (NAFLD) is the most common worldwide and can progress to non-alcoholic steatohepatitis (NASH) and, ultimately, cirrhosis. Clostridioides difficile nosocomial cause of diarrhea associated with worse clinical outcomes in other diseases, including cirrhosis, but has not been extensively evaluated concomitant NAFLD/NASH. We conducted a retrospective cohort study using National Inpatient Sample database from 2015 2017. Patients diagnosis CDI, NAFLD, NASH were...
Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes chronic diseases (CLD) which can progress to cancer. The severity and treatment NAFLD determined by Activity Scores (NAS) fibrosis stage, are usually obtained from biopsy. However, biopsy invasive in nature involves risk procedural complications. Current methods predict NAS scores noninvasive CT images rely heavily on either a large annotated dataset or transfer learning using pretrained networks. availability cannot...
The economic and health care use burdens of Wilson's disease (WD) are unknown. In this study, we aimed to quantify resource burden. We performed a retrospective case-control analysis individuals in the Truven Health MarketScan Commercial Claims database (2007-2017). Using propensity scores, 424 WD cases were matched 1:1 chronic liver (CLD) controls without WD. Total service-specific parameters, expressed monthly averages, quantified for 6-month pre-WD diagnosis versus 12-month period after...
Liver biopsies are traditionally performed using percutaneous, transjugular, or surgical approaches. Endoscopic ultrasound (EUS)-guided liver biopsy is a new modality to sample parenchyma. This technique allows sampling of both lobes and obviates the need for error. However, there paucity literature demonstrating that EUS-guided provides adequate tissue histologic analysis. study aimed review experience 2 large tertiary care centers demonstrate efficacy safety biopsy.