Qingjie Zhang

ORCID: 0000-0001-7298-801X
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About
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Research Areas
  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Adipose Tissue and Metabolism
  • Heme Oxygenase-1 and Carbon Monoxide
  • Neurotransmitter Receptor Influence on Behavior
  • Transcranial Magnetic Stimulation Studies
  • Ubiquitin and proteasome pathways
  • Advanced Glycation End Products research
  • Stress Responses and Cortisol
  • Neurological Disorders and Treatments
  • Neonatal Health and Biochemistry
  • Regional Development and Environment
  • Receptor Mechanisms and Signaling
  • Public Health and Environmental Issues
  • Hydrology and Watershed Management Studies
  • Educational Reforms and Innovations
  • Immune cells in cancer
  • Nerve injury and regeneration
  • Axon Guidance and Neuronal Signaling
  • Ammonia Synthesis and Nitrogen Reduction
  • Alcohol Consumption and Health Effects
  • Stroke Rehabilitation and Recovery
  • Medical Research and Treatments

Peking University
2021-2023

Shandong University
2023

Qingdao University
2023

Affiliated Hospital of Qingdao University
2023

Wuhan University of Technology
2021

Sun Yat-sen University
2014-2018

Third Affiliated Hospital of Sun Yat-sen University
2014-2018

Nantong University
2018

Yellow River Institute of Hydraulic Research
2015

Repetitive transcranial magnetic stimulation (rTMS) has rapidly become an attractive therapeutic approach for stroke. However, the mechanisms underlying this remain elusive. This study aimed to investigate whether high-frequency rTMS improves functional recovery mediated by enhanced neurogenesis and activation of brain-derived neurotrophic factor (BDNF)/tropomyosin-related kinase B (TrkB) pathway compare effect conventional 20 Hz intermittent theta burst (iTBS) on ischemic rats. Rats after...

10.3390/ijms18020455 article EN International Journal of Molecular Sciences 2017-02-20

Although physical exercise is an effective strategy for treatment of ischemic stroke, the underlying protective mechanisms are still not well understood. It has been recently demonstrated that neural progenitor cells play a vital role in recovery neurological function (NF) through differentiation into mature neurons. In current study, we observed significantly reduced infarct size and improved damaged functional after stroke. Furthermore, found only exhibited significant increase number...

10.3390/ijms150610974 article EN International Journal of Molecular Sciences 2014-06-18

Abstract Behavioural sensitization (BS) is characterized by enhanced psychomotor responses to a dose of substance abuse after prior repeated exposure. We previously reported that BS can be induced single injection morphine in rats, whereas septal nuclei are specifically involved the development phase BS. Here, we demonstrated intra‐LS or intra‐MS microinjections also incubated systemic cross‐sensitization fashion, inactivation either subdivision (LS: lateral septum; MS: medial septum) negate...

10.1111/adb.13066 article EN Addiction Biology 2021-05-24

Abstract Aims Opioid addiction is a major public health issue, yet its underlying mechanism still unknown. The aim of this study was to explore the roles ubiquitin–proteasome system (UPS) and regulator G protein signaling 4 (RGS4) in morphine‐induced behavioral sensitization, well‐recognized animal model opioid addiction. Methods We explored characteristics RGS4 expression polyubiquitination development sensitization induced by single morphine exposure rats, effect selective proteasome...

10.1002/brb3.2922 article EN cc-by Brain and Behavior 2023-02-15

Basic materials, basic components, software and algorithms (abbreviated as "Four Foundations") are the cornerstone of development China's industry high-tech industry.The next 15 years will be a critical period for Foundations" to achieve breakthrough against siege, self-reliance, high-quality lead world.Through strategic research, this paper analyzes current situation in China, puts forward core scientific theoretical problems faced by Foundations", suggests that system construction from...

10.15541/jim20210901 article EN Journal of Inorganic Materials 2021-01-01

The engineering area studied in this paper belongs to the areas without hydrological data.The actual measurement data and storm record are both lacked.In paper, different methods were performed for analysis of design flood calculation, at same time, rationality results was also studied.Finally, peak discharge determined.In calculation method equipped with important reference significance small watershed which is lack data.

10.2991/ifeesm-15.2015.296 article EN cc-by-nc 2015-01-01

Background: Although evidence from prior animal and clinical studies indicated exercise is a safe, cost-effective post-stroke rehabilitative intervention, the proper combination of time-window dosage for maximal functional recovery, its underlying mechanisms, are still unknown. Purpose: We aimed to determine optimal intensity by assessing mortality, neurological neurochemical mechanisms in MCAO rats. Methods: The study contained two parts: experiments. In experiment, 8 different groups...

10.1161/str.49.suppl_1.tp98 article EN Stroke 2018-01-22

To investigate the role of high mobility group box 1 (HMGB1) in hepatic endoplasmic reticulum stress (ERS) rats with trauma.Sixty SPF Sprague-Dawley (SD) were randomly divided into groups (n = 6). The rat model liver injury following traumatic was established by continuous compressing bilateral hind-limbs for 3 hours and then intermittent decompressing 30 minutes respectively three times standard weight 15 kg. experiment two groups: control 6, 18, after crush. 2 group, crush (18 crush),...

10.3760/cma.j.issn.2095-4352.2018.04.004 article EN PubMed 2018-04-01
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