A5004270994- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Traditional and Medicinal Uses of Annonaceae
- Traditional Chinese Medicine Analysis
- Alkaloids: synthesis and pharmacology
- Bioactive natural compounds
- Pharmacological Effects of Natural Compounds
- Phytochemical Studies and Bioactivities
- Marine Sponges and Natural Products
- Innovative Educational Techniques
- Cannabis and Cannabinoid Research
- Chemical synthesis and alkaloids
- Plant biochemistry and biosynthesis
- Chromatography in Natural Products
- Phytochemistry and Bioactive Compounds
- Polyamine Metabolism and Applications
- Berberine and alkaloids research
- Biological Activity of Diterpenoids and Biflavonoids
- Seaweed-derived Bioactive Compounds
- Transgenic Plants and Applications
- Phytochemicals and Antioxidant Activities
- Sesquiterpenes and Asteraceae Studies
- Heavy metals in environment
Peking University
2016-2025
Wuhan University of Technology
2012-2025
Shantou University
2014-2025
Shantou University Medical College
2010-2025
Institute of Geographic Sciences and Natural Resources Research
2021-2024
State Key Laboratory of Natural and Biomimetic Drugs
2013-2024
Chinese Academy of Sciences
2011-2024
Shandong Academy of Environmental Science
2024
Nanjing University
2021-2024
University of Chinese Academy of Sciences
2021-2023
Background: Pesticides have been associated with reproductive disorders, but there is limited research on pesticide exposures and human fertility. Objective: We aimed to investigate the effects of preconception exposure pesticides time pregnancy (TTP) infertility in a general population couples planning become pregnant Shanghai, China. Methods: A total 615 women who were enrolled before conception prospectively followed for 1 y observe their TTP. Preconception assessed by measuring urinary...
Helicobacter pylori (H. pylori) eradication is pivotal for alleviating gastric mucosal inflammation and preventing the progression of diseases. While antibiotic-based therapies have achieved significant success in H. eradication, challenges such as antibiotic resistance, drug toxicity, side effects, nonadherence, inapplicability, disruption gastrointestinal microflora emerged. Updated are urgently needed to suppress pylori. Nature has provided multitudinous therapeutic agents since ancient...
Abstract Placenta accreta spectrum (PAS) is a high-risk obstetrical condition associated with significant morbidity and mortality. Current clinical screening modalities for PAS are not always conclusive. Here, we report nanostructure-embedded microchip that efficiently enriches both single clustered circulating trophoblasts (cTBs) from maternal blood detecting PAS. We discover uniquely high prevalence of cTB-clusters in subsequently optimize the device to preserve intactness these clusters....
Five pairs of isoquinoline alkaloid enantiomers, mucroniferanines A-E (1-5), two inseparable epimeric pairs, F and G (6, 7), 10 known alkaloids (8-17) were obtained from Corydalis mucronifera. The structures characterized using spectroscopic data analysis, the absolute configurations established by ECD X-ray analysis. new compounds except for 3 possess a rare 9-methyl group in alkaloids, 2 benzo[1,2-d:3,4-d]bis[1,3]dioxole moieties. It is first report stereoisomerism involving...
Twenty-six glucoconjugated monoterpene indole alkaloids, including 12 new compounds, rhynchophyllosides A–L (1–12), and 14 known ones, 13–26, were obtained from the hook-bearing stems of Uncaria rhynchophylla (Miq.) Miq. ex Havil. Their structures unambiguously elucidated by analyses UV, MS, NMR, ECD, single-crystal X-ray diffraction data. The ESI-MSn behavior glucoalkaloids was also elucidated. Although comprising same glucosyl moiety, aglycone skeletons glucosidic numbers linkage varied...
IR spectroelectrochemistry (EC-IR) is a cutting-edge operando method for exploring electrochemical reaction mechanisms. However, detection of interfacial molecules challenged by the limited sensitivity existing EC-IR platforms due to lack high-enhancement substrates. Here, we propose an innovative plasmon-enhanced infrared (EC-PEIRS) platform overcome this limitation. Plasmonic antennae with ultrahigh signal enhancement are electrically connected via monolayer graphene while preserving...