A5033418391- Prenatal Screening and Diagnostics
- Human Health and Disease
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Pregnancy and preeclampsia studies
- Rheumatoid Arthritis Research and Therapies
- Reproductive Biology and Fertility
- Ectopic Pregnancy Diagnosis and Management
- Endometriosis Research and Treatment
- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Healthcare Systems and Public Health
- Genomic variations and chromosomal abnormalities
- Liver Disease Diagnosis and Treatment
- Alcoholism and Thiamine Deficiency
- Gestational Trophoblastic Disease Studies
- Academic Publishing and Open Access
- Endometrial and Cervical Cancer Treatments
- Autoimmune and Inflammatory Disorders Research
- Ovarian cancer diagnosis and treatment
- Spondyloarthritis Studies and Treatments
- NF-κB Signaling Pathways
- Adrenal Hormones and Disorders
- Antimicrobial Peptides and Activities
- Immune Response and Inflammation
Johns Hopkins Medicine
2021
Johns Hopkins University
2021
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Healthcare of the Russian Federation
2011-2020
National Research University Higher School of Economics
2016
Ministry of Health of the Russian Federation
2003-2014
Chromosomal aneuploidies are known for being the main cause of abnormal development embryos with normal morphology, their implantation failure and early reproductive losses in IVF treatments. Preimplantation genetic screening (PGS) allows selecting chromosomal content increases treatment efficiency due to higher rates less frequent pregnancy losses. New technologies used PGS allow making genome-wide analysis presence all chromosomes embryos. This article presents our study evaluation two...
To determine the most informative markers for assessing functional state of endometrium during 'window implantation' and creating a model assessment readiness embryo implantation. Forty-seven women with tubal infertility successful IVF pregnancy participated in study. Pipelle endometrial sample was performed supposed natural cycle subsequent histological study, transcriptional profile genes GPX3, PAEP, DPP4, TAGLN, HABP2, IMPA2, AQP3, HLA-DOB, MSX1, POSTN determined by real-time quantitative...
Analysis of publication activity in the field biomedicine shows insignificant input Russia world scientific product. This is largely due to lack incentives for researchers. Article describes stimulation researchers Russia, compares it with foreign models, formulates main shortcomings support and research introduces concept effective contract.Development personnel motivation employees organizations health.As a successful experience article implementation contract Veltishev Research Clinical...
Aneuploidies as quantitative chromosome abnormalities are a main cause of failed development morphologically normal embryos, implantation failures, and early reproductive losses. Preimplantation genetic screening (PGS) allows preselection embryos with karyotype, thus increasing the rate reducing frequency pregnancy loss after IVF. Modern PGS technologies based on genome-wide analysis embryo. The first pilot study in Russia was performed to assess possibility using semiconductor...
The article systematizes information on the diagnostic capabilities of modern clinical and laboratory markers ovarian reserve. anti-Mllerian hormone (AMH) as a marker reserve are discussed, which make it possible to adjust dose hormonal drugs predict response ovary stimulation in programs assisted reproductive technologies. This paper discusses for first time role AMH assessing quality oocytes subsequent embryos. Despite insufficient literature data, further study AMH, well full-scale...
Inherited thrombophilia is a condition that predisposes individuals to thrombosis and thromboembolism particularly during pregnancy. Infarction of maternal placental surface (MFI) massive perivillous fibrin deposition (MPVFD) represents specific lesions associated with recurrent adverse fetal outcomes thrombophilic condition.
Human implantation is a complex and multifactorial process.The success of depends on the quality embryos readiness endometrium for embryo nidation.We carried out multivariate analysis expression data endometrial tissue at different stages menstrual cycle to identify potentially informative genes.Further we tested markers determining receptive status using real-time quantitative polymerase chain reaction (qRT-PCR).