- Ovarian function and disorders
- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Gynecological conditions and treatments
- Pregnancy and preeclampsia studies
- Ectopic Pregnancy Diagnosis and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Cutaneous lymphoproliferative disorders research
- Diabetes Management and Research
- Agriculture and Biological Studies
- Medical and Agricultural Research Studies
- Metabolism, Diabetes, and Cancer
- Pancreatic function and diabetes
- Maternal and Neonatal Healthcare
- Dermatological and COVID-19 studies
- Sex and Gender in Healthcare
- Maternal and fetal healthcare
- Pregnancy and Medication Impact
- Cancer Risks and Factors
- Uterine Myomas and Treatments
- Reproductive Health and Technologies
- Autoimmune Bullous Skin Diseases
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Healthcare of the Russian Federation
2013-2022
Hospital at Smolensk Station
2022
Academy of Medical Sciences
2021
To determine the most informative markers for assessing functional state of endometrium during 'window implantation' and creating a model assessment readiness embryo implantation. Forty-seven women with tubal infertility successful IVF pregnancy participated in study. Pipelle endometrial sample was performed supposed natural cycle subsequent histological study, transcriptional profile genes GPX3, PAEP, DPP4, TAGLN, HABP2, IMPA2, AQP3, HLA-DOB, MSX1, POSTN determined by real-time quantitative...
Interleukin 8 (IL-8), vascular endothelial growth factor A (VEGFA), its receptors 1 (VEGFR1) and 2 (VEGFR2) are associated with ovarian hyperstimulation syndrome (OHSS) pathophysiological mechanisms. The aim of this study was to evaluate the concentrations these cytokines depending on way ovulation triggering.A total 51 high-responder patients underwent IVF program received gonadotropin-releasing hormone agonists (GnRHa) trigger + 1500 IU human chorionic gonadotropin (hCG) support oocyte...
Objective The purpose of the study was to evaluate effectiveness controlled ovarian stimulation in different phases menstrual cycle cancer patients seeking for preservation reproductive material before gonadotoxic therapy.Methods A total 140 with oncological diseases underwent standard protocol GnRH antagonists follicular phase (n = 68) and random-start luteal without prescribing 72).Results All included were comparable age AMH level. There no differences mean number oocytes retrieved group,...
Aim. To evaluate the effect of myo-inositol administration in periconceptional period on parameters stimulated cycle, embryological stage and reproductive outcomes vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) programs patients with expected "poor" ovarian response. Design. Рrospective cohort study Materials methods. The prospective included 98 women low reserve, corresponding to groups 3 4 POSEIDON classification (number antral follicles < 5; anti-Mullerian hormone...
Objective. To carry out an analysis of the data available in scientific literature on modern methods influence at endometrial receptivity patients with recurrent implantation failure. Materials and methods. The review includes foreign Russia papers published PubMed during last 7-10 years. Results. There are studies described role scratching, infusion granulocyte colony stimulating factor, autologous peripheral blood mononuclear cells, platelet-rich plasma, array treatment for repeated...
The major limitations associated with gonadotropin-releasing hormone agonist (GnRHa) triggering are inferior clinical outcomes in fresh embryo transfer cycles caused by luteal phase insufficiency following the GnRHa triggering. We included 153 high-risk patients this study. In group I, received trigger + 1,500 IU human chorionic gonadotropin (hCG) support on oocyte pick-up (OPU) day; II, had a dual (GnRHa hCG); and III (control), 10,000 hCG was prescribed for final maturation. levels of LH,...
Aim. To evaluate the hormonal parameters and embryological outcomes of an ovarian stimulation protocol using dydrogesterone to prevent premature LH surge in IVF/ICSI programmes.
 Materials methods. A prospective study randomised, including 79 women with normal reserve undergoing for recombinant FSH (rFSH) from Day 2 or 3 menstrual cycle. surge, participants Group 1 (n=38) received oral 20 mg/day start until day ovulation trigger administration. Participants (n=41) a GnRH antagonist. We...
To optimize the management of infertile women estimation efficacy endoscopic methods treatment (laparoscopy and hysteroscopy) in this category patients was undertaken. With method retrospective analysis clinico- laboratory examination of2785 sterile pairs carried out. The results study showed that are not only most important stage diagnostics but also first pathogenetically substantiated treating female infertility. It became clear half demonstrated from 2 till 5 factors pathogenesis...