A5085327794- Thyroid Cancer Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Nutrition, Genetics, and Disease
- Medical Imaging and Pathology Studies
- Medical Imaging Techniques and Applications
- Human Health and Disease
- BRCA gene mutations in cancer
- Nutritional Studies and Diet
- Radiation Dose and Imaging
- Endometrial and Cervical Cancer Treatments
- HER2/EGFR in Cancer Research
- Photoacoustic and Ultrasonic Imaging
- Cervical Cancer and HPV Research
- Optical Coherence Tomography Applications
- Radiopharmaceutical Chemistry and Applications
- Head and Neck Anomalies
- Genomics and Rare Diseases
- Sodium Intake and Health
- Advances in Oncology and Radiotherapy
- Thyroid and Parathyroid Surgery
- Advanced Fluorescence Microscopy Techniques
- Economic and Financial Impacts of Cancer
- Venous Thromboembolism Diagnosis and Management
- Oral health in cancer treatment
- Chronic Kidney Disease and Diabetes
Saints Cyril and Methodius University of Skopje
2014-2023
University Clinical Center of Kosovo
2021
Institute of public health of Republic of Macedonia
2015
Cancer affects one in three people worldwide. Surgery remains the primary curative option for localized cancers, but good prognoses require complete removal of tumors and timely recognition metastases. To expand surgical capabilities enhance patient outcomes, we developed a six-channel color/near-infrared image sensor inspired by mantis shrimp visual system that enabled near-infrared fluorescence guidance during surgery. The shrimp's unique eye, which maximizes number photons contributing to...
Background Ultrasound guided fine-needle aspiration (FNA) is a standard procedure for thyroid nodules management and selecting patients surgical treatment. Atypia of undetermined significance (AUS) or follicular lesion (FLUS), as stated by The Bethesda System Reporting Thyroid Cytopathology, diagnostic category with an implied malignancy risk 5-15%. aim our study was to review cytology histopathology reports, well clinical ultrasound data, reported AUS/FLUS, in order evaluate the rate assess...
BACKGROUND: Thyroid uptake of technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) during parathyroid scintigraphy can be affected by various conditions.AIM: To evaluate the frequency absent 99mTc-MIBI thyroid gland in early phase dual-phase scintigraphy.METHODS: The planar images dual Tc99m MIBI from 217 patients performed between 2014 and 2017 were retrospectively analysed. Patients divided into two groups. first group included 147 with primary hyperparathyroidism second 70 chronic renal...
Abstract Patients undergoing mechanical ventilation in intensive care units (ICUs) may develop ventilator-induced lung injury (VILI). Beside the high tidal volume (Vt) and plateau pressure (Pplat), hyperoxia is supposed to precipitate injury. Oxygen toxicity presumed occur at levels of fraction inspired oxygen (FiO 2 ) exceeding 0.40. The exposure time certainly very important patients who spend extended on (MV) are probably more exposed severe hyperoxic acute (HALI). Together, biotrauma...
Colorectal cancer (CRC) is the second commonest in women, third men, being fourth cause of death. The most important factor for prognosis and staging CRC patients status regional lymph nodes (LN).To implement method sentinel node (SLN) detection using radiocolloid, test its rate, sensitivity, accuracy, negative predictive value possibility upstaging.The study included 40 patients, age 63 ± 14 years, without LNs detected on CT or MRI. SLN was performed after endoscopically peri- intratumoral...
Near-infrared fluorescence image-guided surgery is often thought of as a spectral imaging problem where the channel count critical parameter, but it should also be multiscale field view and spatial resolution are similarly important.
Introduction Muscle perfusion is a physiologic process that can undergo quantitative assessment and thus define the range of normal values indexes reserve. The investigation microcirculation has crucial role in determining muscle perfusion. Materials method study included 30 examinees, 24-74 years age, without history confirmed peripheral artery disease all had findings on Doppler ultrasonography pedo-brachial index lower extremity (PBI). 99mTc-MIBI tissue scintigraphy limbs evaluates...
Abstract Objectives Many studies have shown that socio-economic status (SES) contributes to health inequalities, with nutrition as one of the major risk factors. Iodine intake entirely depends on external sources, and deficiencies are known be more prevalent in lower social groups, especially countries limited access iodized salt. This study aimed determine influence SES iodine availability from household salt North Macedonia. Methods Using cluster sampling, 1,200 children were recruited,...
Objectives The aim of our study was to evaluate the survival rate all thyroid carcinomas (TCs) diagnosed in 1999-2015 period Republic North Macedonia and analyze prognostic influence several characteristics on development distant metastases, as well effect seven clinical constitutional features mortality. Material methods A retrospective analysis medical data from TCs performed. types estimated using Kaplan Meier method. Univariate multivariate logistic regression applied for evaluation...
OBJECTIVE: Our goal was to evaluate the analytical performance of novel immunoassay platform and compare agreement between thyroid-stimulating hormone (TSH) FT4 results, obtained by currently used platform.
 MATERIALS AND METHODS: Both platforms, current Immulite 2000 Maglumi 800, are based on chemiluminecsence method. Analytical evaluated use serum pools commercial quality control samples. The comparison study carried out with 80 Obtained results were analyzed descriptive statistics,...
Abstract Many studies have shown that socio-economic status (SES) contributes to health inequalities, with nutrition as one of the major risk factors. Iodine intake entirely depends on external sources, and deficiencies are known be more prevalent in lower social groups, especially countries limited access iodized salt. This study aimed determine influence SES iodine availability from household salt North Macedonia. Using cluster sampling, 1,200 children were recruited, 1,191 participated...
Sentinel lymph node (SLN) mapping allows minimal invasive assessment of status in patients with early-stage endometrial cancer (EC). Intraoperative detection SLNs is based on the results obtained from preoperative nuclear medical images. The purpose this study was to compare data planar lymphoscintigraphy (PL), single-photon emission computed tomography (SPECT), and SPECT (SPECT/CT) for SLN EC.A total 44 images 22 EC (22 PL, 9 13 SPECT/CT) were analyzed. scans performed period 2018-2020 at...
The staging of solid cancers is critical to the planning both primary treatment with surgery and adjuvant therapies like chemotherapy; however, not always possible preoperative information may require intraoperative evaluation sentinel lymph nodes confirm or disaffirm presence metastasis. Challenges are presented by standard-of-care node dissection which must be quick accurate enough guide surgical strategy despite a workflow that stretches from operating room pathology lab; solution posed...
Abstract Medullary thyroid carcinomas (MTCs) are rare neoplasms comprising 2-10% of all malignnancies. More than 75% sporadic tumors and the remainder is familial MEN2 related. Both syndromic MTCs frequently show mutations in RET proto-oncogene. It has been noted that some MTC cases present an indolent, aggressive clinical course. Ki-67 expression generally low, with documented exceptions, whereas high Bcl-2 reported majority cases. Some studies have shown expressions prognostic value, as...