A5015401716- Medical Imaging Techniques and Applications
- Lymphoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Breast Cancer Treatment Studies
- Inflammatory Bowel Disease
- Lung Cancer Treatments and Mutations
- Radiation Dose and Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Microscopic Colitis
- Radiopharmaceutical Chemistry and Applications
- Spondyloarthritis Studies and Treatments
- Advanced X-ray and CT Imaging
- COVID-19 diagnosis using AI
- Cancer Treatment and Pharmacology
- CNS Lymphoma Diagnosis and Treatment
- Glycogen Storage Diseases and Myoclonus
- Neurological disorders and treatments
- Adipose Tissue and Metabolism
- Ultrasound in Clinical Applications
- HER2/EGFR in Cancer Research
- Advanced Radiotherapy Techniques
- Multiple Myeloma Research and Treatments
- Advances in Oncology and Radiotherapy
- Liver physiology and pathology
- Chronic Lymphocytic Leukemia Research
Semmelweis University
2013-2024
Interim 18F-fluorodeoxyglucose positron emission tomography (Interim-18F-FDG-PET, hereafter I-PET) has the potential to guide treatment of patients with diffuse large B-cell lymphoma (DLBCL) if prognostic value is known. The aim this study was determine optimal timing and response criteria for evaluating prognosis I-PET in DLBCL. Individual patient data from 1692 de novo DLBCL were combined scans harmonized. performed at various time points during rituximab plus cyclophosphamide,...
Convolutional neural networks (CNNs) may improve response prediction in diffuse large B-cell lymphoma (DLBCL). The aim of this study was to investigate the feasibility a CNN using maximum intensity projection (MIP) images from 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) baseline scans predict probability time-to-progression (TTP) within 2 years and compare it with International Prognostic Index (IPI), i.e. clinically used score. 296 DLBCL 18F-FDG PET/CT collected...
The aim of this study was to validate a previously developed deep learning model in 5 independent clinical trials. predictive performance compared with the international prognostic index (IPI) and 2 models incorporating radiomic PET/CT features (clinical PET models).
We performed a systematic survey to assess the existing gaps in Europe multidisciplinary education for integration of radioligand therapy (RLT) into cancer care and obtain detailed information on current limitations key contents relevant.A high-quality questionnaire, with emphasis scales, formulation, validity different items, was designed. An expert validation process undertaken. The circulated among medical specialties involved treatment, universities, nursing organizations. Questionnaires...
Objective 2-[ 18 F]fluoro-2-deoxy- d -glucose PET/computed tomography ([ F]FDG-PET/CT) is a widely used imaging method in the management of diffuse large B-cell lymphomas (DLBCL). Our aim was to investigate prognostic performance different PET biomarkers multicenter setting. Methods We investigated baseline volumetric values [metabolic tumor volume (MTV) and total lesion glycolysis (TLG), also normalized for body weight] segmented with three methods [>SUV4 (glob4); 41% isocontour (41pc),...
Absztrakt Esetismertetés: 75 éves, nagyméretű, többgócú colorectalis májmetastasisban szenvedő nőbeteg esetét ismertetjük. Májsebészeti konzíliumát megelőzően többféle protokoll szerint több széria kemoterápiában részesült. A kezelések ellenére a korábban pár centiméteres metastasis mérete 5 hónap alatt mintegy háromszorosára nőtt. Az áttét kiterjesztett jobb oldali hemihepatectomiával technikailag eltávolítható lett volna, azonban maradék májtömeg (FLR) kevésnek bizonyult. FLR indukált...
AimTo evaluate (I) trastuzumab-containing primary systemic therapy (PST) in human epidermal growth factor receptor 2 (Her2) overexpressing breast carcinomas; (II) compare the patients who achieved and those did not achieve pathological complete remission (pCR), (III) analyze accuracy of different clinical-imaging modalities tumor response monitoring.Methods188 received PST between 2008 2014 were reviewed 43 Her2 cancer (28 Luminal B/Her2-positive 15 Her2-positive) enrolled. 26 mostly...
FDG-PET-CT is highly sensitive in detection of viable tumour tissue, giving an importance for that oncological diagnostics.The authors analysed retrospectively the relationship between metabolic response and changes Ki-67, a proliferation marker.Staging scans (before after therapy) SUVs (Standardized Uptake Value), morphological primary axillary lymph node region were evaluated 30 patients with breast cancer. Calculated ΔSUV compared Ki-67 marker (measured biopsies surgical specimens).The...
Abstract Objective We aimed to study the possible factors influencing visualisation of brown adipose tissue (BAT) on FDG PET/CT at diagnosis in children. Method A total 92 children or adolescents were included (63 patients with Hodgkin lymphoma (HL) and 29 sarcoma). examined images obtained searched for uptake BAT. analysed relationship between BAT activation different factors, such as age, sex, outside temperature season, histological type malignancy (HL sarcoma), volumetric metabolic...
e12010 Background: We analyzed the accuracy of different response evaluation score systems in a group breast cancer patients treated with primary systemic therapy (PST). The tested were based on metabolical, morphological and proliferation markers tumor response. Methods: report 42 whom staging FDG-PET/CTs carried out before after PST. Maximal SUVs (Standardized Uptake Values) changes evaluated (PT) axillary lymph node (AL) region. Ki-67 labeling indexes (LI) measured core-biopsies surgical...
We report the palliative embolization and functional imaging follow-up of a recurrent shoulder plasmacytoma. The multiple myeloma patient complained severe pain discomfort, while he could not tolerate further chemotherapy. left lesion had earlier received high dose irradiation. Thus, well-vascularized was embolized via feeding arteries branching off from subclavian artery in two sessions. patient’s symptoms rapidly improved post-embolization serum free light chain ratio stabilized at lower...
Guideline recommendations for diffuse large-B-cell lymphoma (DLBCL) treatment are shifting from long to short duration, although it is still unclear whether shortening duration does not cause any harm. As interim PET (I-PET) has high negative predictive value progression, we evaluated the cost-effectiveness of dependent on I-PET result. We developed a Markov cohort model using Re-Analysis (PETRA) database evaluate (LTD) strategy, ie 8x R-CHOP or 6x plus 2 R, and (STD) R-CHOP. Strategies were...