A5058310580- Epilepsy research and treatment
- Advanced MRI Techniques and Applications
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects and Toxicity Studies
- Neurological disorders and treatments
- Acute Ischemic Stroke Management
- Infectious Encephalopathies and Encephalitis
- Multiple Sclerosis Research Studies
- Cerebrovascular and Carotid Artery Diseases
- Metabolism and Genetic Disorders
- Functional Brain Connectivity Studies
- Cerebrospinal fluid and hydrocephalus
- Autoimmune Neurological Disorders and Treatments
- EEG and Brain-Computer Interfaces
- Neurosurgical Procedures and Complications
- Genetics and Neurodevelopmental Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Sleep and Wakefulness Research
- Fetal and Pediatric Neurological Disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Glioma Diagnosis and Treatment
- Diet and metabolism studies
- Neurological and metabolic disorders
- Spine and Intervertebral Disc Pathology
- Polyomavirus and related diseases
Semmelweis University
2016-2025
HUN-REN Research Centre for Natural Sciences
2023
Hospices Civils de Lyon
2022
Hôpital Femme Mère Enfant
2022
University of Pecs
2006-2019
Országos Idegsebészeti Tudományos Intézet
2017
CS Diagnostics
2008
University of Szeged
2006
Hungarian Academy of Sciences
2006
Institute of Psychiatry and Neurology
1992-2005
Ripples are high-frequency oscillation bursts in the mammalian hippocampus mainly present during Non-REM sleep. In rodents they occur association with sharp waves and grouped by cortical slow such that, parallel sleep spindles, ripple activity is suppressed hyperpolarized down-state enhanced depolarized up-state. The temporal coupling between oscillations, spindles ripples has been suggested to serve a hippocampo-neocortical dialogue underlying memory consolidation Here, we examined whether...
The aim of this study was to characterize the ultrasonographic findings on nerves in neuralgic amyotrophy.Fourteen patients with amyotrophy were examined using high-resolution ultrasound.Four types abnormalities found: (1) focal or diffuse nerve/fascicle enlargement (57%); (2) incomplete nerve constriction (36%); (3) complete torsion (50%; hourglass-like appearance); and (4) fascicular entwinement (28%). Torsions confirmed intraoperatively seen radial 85% patients. A significant correlation...
ABSTRACT Introduction The aim of this study was to assess the value ultrasonography in neuralgic amyotrophy. Methods Fifty‐three patients with 70 affected nerves were examined high‐resolution ultrasound. Results most commonly nerve anterior interosseous (23%). Ultrasonographic abnormalities nerves, rather than brachial plexus, observed, an overall sensitivity 74%. Findings included swelling nerve/fascicle or without incomplete/complete constriction and rotational phenomena (nerve torsion...
Summary Objective In 2014 the European Union–funded E‐ PILEPSY project was launched to improve awareness of, and accessibility to, epilepsy surgery across Europe. We aimed investigate current use of neuroimaging, electromagnetic source localization, imaging postprocessing procedures in participating centers. Methods A survey on clinical imaging, methods candidates distributed among 25 centers consortium. descriptive analysis performed, results were compared existing guidelines...
Head motion artifacts in magnetic resonance imaging (MRI) are an important confounding factor concerning brain research as well clinical practice. For this reason, several machine learning-based methods have been developed for the automatic quality control of structural MRI scans. Deep learning offers a promising solution to problem, however, given its data-hungry nature and scarcity expert-annotated datasets, advantage over traditional identifying motion-corrupted scans is yet be...
Abstract Current European Stroke Organisation (ESO) guidelines recommend extended time window reperfusion therapies (4.5–9 h for thrombolysis, 6–24 thrombectomy) based on advanced imaging. However, the workload and clinical benefit of this strategy a population basis are not known. To determine caseload, treatment rates, outcomes in as compared to standard windows. All consecutive ischaemic stroke patients within 24 last known well between 1st March 2021 28th February 2022 were included...
Summary: Purpose: Severe myoclonic epilepsy in infancy (SMEI; Dravet's syndrome) is a malignant syndrome characterized by early prolonged febrile convulsions (PFCs) with secondary psychomotor delay and variety of therapy‐resistant seizures. Although the initial symptoms are repeated PFCs, MRI performed at onset disease shows no hippocampal structural abnormalities. We aimed to assess clinical serial data patients SMEI special attention temporomedial structures. To our knowledge, this first...
To describe an unusual clinical presentation of a patient with voltage-gated potassium channel Ab- positive, non-paraneoplastic limbic encephalitis.We performed video-EEG monitoring, structural MRI, (18)F-FDG-PET, (1)H-MRS, neuropsychological testing and antibody serology.A 42-year-old male presented in acute phase encephalitis confirmed by antibodies to channels. His pilomotor status was pharmacoresistant antiepileptic drugs, but responded corticosteroid azathioprine treatment. The MRI...
It is unclear whether the hippocampal abnormality in temporal lobe epilepsy (TLE) a consequence or cause of afebrile febrile seizures (FSs). We investigated abnormalities are present healthy adults>15 years after simple FS.Eight subjects (5 men) with history FS (FS+ group) and eight sex- aged-matched control (FS- were by three MR methods: blinded visual inspection MRI pictures; automatic voxel-based volumetry; T2 relaxation time measurements.The mean total volume two hippocampi was 5.36 +/-...
The objective of this study was to determine the incidence posttraumatic hydrocephalus (PTH) among patients in our rehabilitation unit for traumatic brain injury. Furthermore, we aimed assess effect shunt implantation and identify postoperative complication rate. This is a retrospective cohort study, which between 2000 2009, data were collected from inpatients with injury complicated by PTH. During period, 55 presented PTH; all these underwent ventricular implantation. PTH treated 4.8%. mean...
The consequences of cerebral infarcts involving the left hemisphere differ from those right homologue areas. Data 337 consecutive, unselected patients with acute ischaemic stroke in territory or middle artery were analysed. Furthermore, lesion locations 77 early death compared 315 followed for more than 28 days. Without any differences severity and volume lesions, outcome strokes was less favourable, case fatality rate higher controls during a 10-year follow-up period. due to cardiogenic...
When MRI fails to detect a potentially epileptogenic lesion, the chance of favorable outcome after epilepsy surgery becomes significantly lower (from 60 90% 20-65%). Hybrid FDG-PET/MRI may provide additional information for identifying zone. We aimed investigate possible effect introduction hybrid into algorithm decision-making in both lesional and non-lesional drug-resistant epileptic patients.In prospective study patients suffering from focal epilepsy, 30 nonlesional cases with discordant...
The aim of our prospective study was to evaluate the clinical impact hybrid [18F]-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ([18F]-FDG PET/MRI) on decision workflow epileptic patients with discordant electroclinical and MRI data. A novel mathematical model introduced for a concordance calculation supporting classification by subgroups decisions. Fifty-nine diagnostic results or negativity were included in this study. value PET/MRI compared other modalities...
Temporal lobe epilepsy (TLE) is frequently associated with hippocampal sclerosis (HS) and a history of febrile convulsions (HFC). The authors investigated 292 patients TLE due to HS. Left HS occurred more (57%) than right (43%, <i>p</i> = 0.01). Forty-seven percent the had HFC. In HS, HFC in 59.6%, whereas left was present 37.5%, showing highly significant lateralization difference.