A5012244506- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Liver Disease Diagnosis and Treatment
- Peripheral Artery Disease Management
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Venous Thromboembolism Diagnosis and Management
- Intracranial Aneurysms: Treatment and Complications
- Renal cell carcinoma treatment
- Vascular Procedures and Complications
- Uterine Myomas and Treatments
- Acute Ischemic Stroke Management
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- MRI in cancer diagnosis
- Aortic aneurysm repair treatments
- Diagnosis and Treatment of Venous Diseases
- Endometriosis Research and Treatment
- Central Venous Catheters and Hemodialysis
- Pediatric Urology and Nephrology Studies
- Heart Rate Variability and Autonomic Control
- Cardiac electrophysiology and arrhythmias
- Renal and Vascular Pathologies
- Liver Disease and Transplantation
- Ion channel regulation and function
Semmelweis University
2015-2025
Imaging Center
2021
Methodist Hospital
2015
Hungarian Academy of Sciences
2012
Houston Methodist
2012
Sapienza University of Rome
2012
University of Padua
2012
Northern General Hospital
2003-2007
Graz University Hospital
2002
Maastricht University
1997
Background Intravenous anesthetics etomidate, propofol, and midazolam produce negative inotropic effects of various degrees. The mechanism underlying these differences is largely unknown. Methods intravenous on L-type Ca2+, transient outward inward-rectifier K+ channel currents (ICa, IKto, IK1) were compared in canine ventricular cells using the whole-cell voltage-clamp technique. ICa IK elicited by progressively depolarizing from -40 to +40 mV, -90 +60 respectively. peak amplitude...
Background: we evaluated regression models based on quantitative ultrasound (QUS) parameters and compared them with a vendor-provided method for calculating the fat fraction (USFF) in metabolic dysfunction-associated steatotic liver disease (MASLD). Methods: We measured attenuation coefficient (AC) backscatter-distribution (BSC-D) determined USFF during calculated magnetic resonance imaging proton-density (MRI-PDFF) steatosis grade (S0-S4) combined retrospective-prospective cohort. trained...
Abstract Background Non‐alcoholic fatty liver disease ( NAFLD ) has been linked to increased cardiovascular morbidity. However, genetic factors have an unclear role in this condition. Aims To analyse heritability of and its association with abnormal vascular parameters a large twin cohort. Methods Anthropometric lipid metabolic were obtained from 208 adult Hungarian twins (63 monozygotic 41 dizygotic pairs; 58 men 150 women; age 43.7 ± 16.7 years). B‐mode ultrasonography was performed detect...
Objective: Central blood pressure and aortic stiffness have been consistently reported as strong cardiovascular risk factors. Twin studies by comparing identical with nonidentical twins produce information on the relative contribution of genes environment. Methods: One hundred fifty-four monozygotic (MZ) 42 dizygotic (DZ) twin pairs (age 43 ± 17 years) from Hungary United States underwent brachial central augmentation index (AIx), pressure, pulse wave velocity (PWV) measurements invasively...
Whole-body magnetic resonance imaging (WB-MRI) and angiography (WB-MRA) has become increasingly popular in population-based research. We evaluated retrospectively the frequency of potentially relevant incidental findings throughout body.
Abstract Background CT texture analysis (CTTA) has been successfully used to assess tissue heterogeneity in multiple diseases. The purpose of this work is demonstrate the value three-dimensional CTTA evaluation diffuse liver disease. We aimed develop based prediction models, which can be for staging fibrosis different anatomic segments irrespective variations scanning parameters. Methods retrospectively collected scans thirty-two chronic hepatitis patients with fibrosis. examinations were...
Few family studies reported moderate genetic impact on the presence and scores of carotid plaques. However, heritability plaque characteristics remains still unclear. Twin more reliably estimate relative contribution genes to these traits in contrast study design.One hundred ninety-two monozygotic 83 dizygotic adult twin pairs (age 49±15 years) from Italy, Hungary, United States underwent B-mode color Doppler ultrasound bilateral common, internal, external arteries.Age-, sex-,...
Conventional clear cell renal carcinoma (ccRCC) and papillary (pRCC) have different behavioral characteristics clinical management strategies (nephrectomy vs. nephron-sparing surgery). Our aim was to retrospectively evaluate the contrast enhancement pattern of ccRCC pRCC its possible diagnostic role for preoperative differentiation using a standardized protocol.Quadriphasic multidetector computed tomography (CT) images (unenhanced, corticomedullary, nephrographic, excretory phases) 19...
Background The nature of input data is an essential factor when training neural networks. Research concerning magnetic resonance imaging (MRI)-based diagnosis liver tumors using deep learning has been rapidly advancing. Still, evidence to support the utilization multi-dimensional and multi-parametric image lacking. Due higher information content, three-dimensional should presumably result in classification precision. Also, differentiation between focal lesions (FLLs) can only be plausible...
Purpose To evaluate factors associated with pseudoaneurysm (PSA) development. Methods Between January 2016 and May 2020, 30,196 patients had invasive vascular radiological or cardiac endovascular procedures that required arterial puncture. All PSA were identified. A matched (age, gender, type of the procedure) control group 134 was created to reveal predictors formation. Results Single PSAs found in patients. Fifty-three developed after (53/6555 [0.8%]), 31 coronary artery (31/18038 [0.2%]),...
Abstract Purpose The aim of this article is to present our experience with minimally-invasive treatment for nulliparous patients pelvic venous congestion syndrome (PVCS) special attention anatomical considerations, procedural and clinical outcome. Materials Methods In retrospective, monocentric study, 21 PVCS treated from January 2014 June 2023 were included. preprocedural imaging evaluation was based on color Doppler ultrasound, contrast-enhanced CT and/or MRI. all cases insufficient...
Active and passive mechanical properties of human saphenous canine femoral vein segments were measured in vitro to assess the degree pressure-dependent venous myogenic tone (% change diameter, physiological saline solution vs. Ca(2+)-free solution) these vessels. Stepwise elevation intraluminal pressure from 2 20 mmHg caused an active response, which was calcium dependent. Side branches veins (OD at mmHg: 1.92 +/- 0.15 mm control; 2.41 0.18 relaxed) displayed a larger (approximately 25%)...
Pressurization of isolated arteries may result in Ca(2+)-dependent contraction and membrane depolarization. Because the open state probability some vascular muscle K+ channels is augmented by rises cytosolic Ca2+ depolarization, we investigated possibility that increases intraluminal pressure activate isolated, perfused rat saphenous arteries. Stepwise from 5 to 205 mm Hg resulted increasing, active arterial contraction, measured as smaller diameters physiological salt solution than...