- Anesthesia and Pain Management
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Nausea and vomiting management
- Spine and Intervertebral Disc Pathology
- Cardiac Ischemia and Reperfusion
- Enhanced Recovery After Surgery
- Nutrition and Health in Aging
- Peripheral Neuropathies and Disorders
- Sleep and Wakefulness Research
- Pain Mechanisms and Treatments
- Music Therapy and Health
- Sleep and related disorders
- Aortic aneurysm repair treatments
- Innovations in Medical Education
- Aortic Disease and Treatment Approaches
- Shoulder Injury and Treatment
- Cardiac Arrest and Resuscitation
- Cardiovascular Disease and Adiposity
- Histone Deacetylase Inhibitors Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Empathy and Medical Education
- Healthcare professionals’ stress and burnout
- Obesity, Physical Activity, Diet
First Affiliated Hospital of Gannan Medical University
2021-2025
Gannan Medical University
2024
Soochow University
2024
Ganzhou People's Hospital
2023
Neuropathic pain (NP) represents a broad scope of various pathological ramifications the nervous system. Remimazolam is proved sedative in treating neuropathic pain. Considering Bradykinin receptor's vital role and potentials receptor B1 (BDKRB1) pain-signalling pathway, we nominated them as primary target for remimazolam.
Postoperative cognitive dysfunction (POCD) is a common postsurgical complication in elderly individuals, significantly impacting the quality of life patients; however, there currently no effective clinical treatment for POCD. Recent studies have shown that Icariin (ICA) has antiaging effects and improves function, but its effect POCD not been studied. In this study, we investigated influence ICA on function TLR4/NF-κB signaling pathway rat model. We found reduced surgery-induced memory...
Abstract Objective: The relationship of a diet low in fibre with mortality has not been evaluated. This study aims to assess the burden non-communicable chronic diseases (NCD) attributable globally from 1990 2019. Design: All data were Global Burden Disease (GBD) Study 2019, which mortality, disability-adjusted life-years (DALY) and years lived disability (YLD) estimated Bayesian geospatial regression using at global, regional country level acquired an extensively systematic review. Setting:...
This study aimed to explore the current situation regarding medical students' professional identity after COVID-19 in China, as well factors that influence it. Questionnaire compiled by Fujian Medical University and self-designed were used, participators from one Jiangxi Province, a central city of China. Results showed students was upper middle level attitude generally positive. There significant sex difference terms value (t = 2.057, p < 0.05) which scores for boys higher than girls,...
Objective This study aimed to evaluate the effect of perioperative transcutaneous electrical acupoint stimulation (TEAS) on postoperative cognitive dysfunction (POCD) in older patients with lumbar spine surgery. Methods Older (aged 60–80 years old) receiving surgery under general anesthesia were randomly divided into group A, 3-day intervention group; B, 7-day control C, sham TEAS group, selected “Baihui” (GV 20) and “Dazhui” 14) point was intervened once 30 min before operation “HANS”...
Objective This study aimed to find the best dose of dexmedetomidine in spinal anesthesia for cesarean section. Methods 120 American Society Anesthesiologists (ASA) Class I and II parturients undergoing elective delivery under were randomly allocated into four groups treated with intrathecal ropivacaine (12 mg) alone (Group R) or combination 5 μg RD1), 7.5 RD2) 10 RD3). Characteristics anesthesia, hemodynamic changes, adverse effects, stress reactions neonatal outcomes recorded groups....
The existing data do not consistently support the link between elderly adults' waist circumferences and sleep disorders. This study aimed to evaluate whether circumference was connected with disorder in elderly. cross-sectional utilized from 2005-2018 National Health Nutrition Examination Survey (NHANES) regarding circumference, disorders, confounding factors. Included were participants older than 60 who completed questionnaires measurements. Using a multivariate logistic regression model...
Several patients with pre-operative anxiety and insomnia refuse to take sleeping pills because of the side effects pills. This study aimed evaluate applicability intranasal dexmedetomidine (DEX) in treatment insomnia.A total 72 were randomly divided into two groups DEX (n = 36) normal saline (NS, n 36). The primary outcomes included patients' time fall asleep, sleep time, severity index (ISI) after treatment, satisfaction effect. secondary mean arterial pressure (MAP), oxygen saturation...
The aim of this study was to observe the intraoperative and postoperative analgesic effects suprainguinal fascia iliaca compartment block (SFICB) combined with sciatic nerve (SNB) in patients undergoing total hip arthroplasty (THA).
To evaluate the efficacy and safety of intranasal dexmedetomidine (Dex), oral lorazepam, a placebo in managing preoperative anxiety-related insomnia.
This study aimed to investigate the analgesic effect of ultrasound-guided transversus thoracis plane block (TTPB) combined with intermediate cervical plexus (ICPB) in early postoperative period after trans-areolar endoscopic thyroidectomy.A total 62 female patients undergoing thyroidectomy were randomly classified TTPB ICPB group ropivacaine (block group) or superficial (control group). The primary outcome measures resting visual analogue scale (VAS) chest area at 6 h surgery. secondary...
Abstract Background One-lung ventilation (OLV) is often used during lobectomy anesthesia. Inflammation and oxidative stress OLV can aggravate lung tissue injury, which an important factor causing postoperative acute injury. Studies have confirmed that remote ischemic preconditioning (RIPC) initiate endogenous protective mechanisms alleviate injury to target organs. However, whether RIPC has a effect in patients undergoing resection remains unknown. Therefore, this randomized controlled...
Background The objective of this study was to find ways reduce intraoperative glandular secretion in patients by observing the effects different depths anesthesia on under Narcotrend monitoring (NT), use unnecessary anticholinergic drugs, and improve quality patient comfort. Methods Ninety who underwent total laparoscopic hysterectomy were randomly divided into three groups. Group L: maintenance depth D0–D2, group M: E0–E1, H: long tocopherol 0.01 mg/kg administered intravenously 10 min...
Abstract Background: The objective of this study was to find ways reduce intraoperative glandular secretion in patients by observing the effects different depths anesthesia on under Narcotrend monitoring (NT), use unnecessary anticholinergic drugs, and improve quality patient comfort. Methods: Ninety who underwent total laparoscopic hysterectomy were randomly divided into four groups. Group L: maintenance depth D0-D2, group M: E0-E1, H: long tocopherol 0.01 mg/kg administered intravenously...