A5100421860- Streptococcal Infections and Treatments
- Antimicrobial Resistance in Staphylococcus
- Neonatal and Maternal Infections
- Bacterial biofilms and quorum sensing
- Infections and bacterial resistance
- Microbial infections and disease research
- Antibiotic Resistance in Bacteria
- Infective Endocarditis Diagnosis and Management
- Vibrio bacteria research studies
- Bacterial Genetics and Biotechnology
- Aquaculture disease management and microbiota
- Bacteriophages and microbial interactions
- Legionella and Acanthamoeba research
- Yersinia bacterium, plague, ectoparasites research
- Oral microbiology and periodontitis research
- Plant Pathogenic Bacteria Studies
- Toxin Mechanisms and Immunotoxins
- Genomics and Phylogenetic Studies
- Malaria Research and Control
- Biochemical and Structural Characterization
- Bacterial Infections and Vaccines
- Escherichia coli research studies
- Bacillus and Francisella bacterial research
- Mosquito-borne diseases and control
- Parasitic Infections and Diagnostics
Yunnan Agricultural University
2025
First Affiliated Hospital Zhejiang University
2025
Northeast Forestry University
2025
Luoyang Normal University
2015-2024
Hebei Agricultural University
2023-2024
Luoyang Institute of Science and Technology
2019-2024
Fujian Agriculture and Forestry University
2024
Peking University
2016-2024
First Affiliated Hospital of Nanchang University
2023
Nanchang University
2023
Dispersion is a process used by bacteria to successfully transit from biofilm planktonic growth state and spawn novel communities in new locales. Alterations bis-(3'-5')-cyclic dimeric GMP (c-di-GMP) levels have been shown be associated with dispersal number of different bacteria. The signaling molecule nitric oxide (NO) known induce dispersion through stimulation c-di-GMP-degrading phosphodiesterase (PDE) activity. However, no c-di-GMP modulating enzyme directly involved NO-induced has yet...
Streptococcus suis (S. suis), more specifically serotype 2, is a bacterial pathogen that threatens the lives of pigs and humans. Like many other pathogens, S. exhibits quorum sensing (QS) system-controlled virulence factors, such as biofilm formation complicates treatment. Therefore, impairing QS involving LuxS/AI-2 cycle in suis, may be promising alternative strategy for overcoming infections. In this study, we investigated paeoniflorin (PF), monoterpenoid glycoside compound extracted from...
Streptococcus suis (S. suis) is a zoonotic pathogen with global distribution, which causes serious diseases in both humans and animals economic losses the swine industry. As antibiotic resistance increases, there an urgent imperative to explore novel antibacterial alternatives. In present study, we selected anticancer drug 5-fluorouracil (5-FU) approved by Food Drug Administration (FDA) as candidate treat S. infections. The results showed that various pathogens, especially suis, are more...
Streptococcus suis (SS) is a zoonotic pathogen that causes severe disease symptoms in pigs and humans. Biofilms of SS bind to extracellular matrix proteins both endothelial epithelial cells cause persistent infections. In this study, the differences protein expression profiles grown either as planktonic or biofilms were identified using comparative proteomic analysis. The results revealed existence 13 varying amounts, among which six upregulated seven downregulated biofilm compared with...
Abstract Bacteria utilize intercellular communication to orchestrate essential cellular processes, adapt environmental changes, develop antibiotic tolerance, and enhance virulence. This communication, known as quorum sensing (QS), is mediated by the exchange of small signalling molecules called autoinducers. AI-2 QS, regulated metabolic enzyme LuxS (S-ribosylhomocysteine lyase), acts a universal mechanism across gram-positive gram-negative bacteria crucial for diverse bacterial processes. In...
Abstract Background The genus Providencia includes species of ecological and clinical significance, with some acting as opportunistic pathogens in hospital-acquired infections such urinary tract infection (UTI). However, overlapping phenotypic traits genetic similarities pose challenges for accurate characterization. This study exemplifies this challenge by identifying a novel isolate through genomic analysis. Results In study, strain PAZ2 was isolated from the urine sample hospitalized...
Abstract The biofilm acts as a protective layer for Streptococcus suis ( S. ), contributing to the development of drug resistance and chronic infections. Autoinducer 2 (AI-2) quorum sensing represents primary regulatory pathway governing formation in . Consequently, targeting AI-2 inhibit promising strategy preventing managing infections caused by This study established small natural product library integrating commercial molecules with Chinese herbal medicine molecules. two products,...
The global rise in multidrug-resistant bacteria has significantly undermined the efficacy of traditional antibiotics. Multidrug-resistant Streptococcus suis (S. suis), a pathogen capable infecting pigs and humans, been identified as critical threat, causing severe meningitis rapid mortality. In response, researchers have increasingly focused on herbal compounds non-traditional antimicrobial agents, which can inhibit bacterial growth while minimizing risk resistance development. This study...
AbstractH13 and H16 subtype avian influenza viruses (AIVs) typically infect Charadriiformes, are widely distributed throughout coastal regions worldwide, pose a risk of spillover to mammals. Systematic research on the epidemiology, transmission dynamics, biological characteristics these subtypes remains limited. To address this gap, we analyzed 20 years wild bird surveillance data from China integrated with global database information reconstruct spatiotemporal distribution, dynamics public...
Streptococcus equi subsp. zooepidemicus is an opportunistic pathogen. It has caused a very large economic loss in the swine industry of China and become threat to human health. We announce complete genome sequence S. strain ATCC 35246, which provides opportunities understand its pathogenesis mechanism genetic basis.