A5100325763- Computational Drug Discovery Methods
- Environmental Toxicology and Ecotoxicology
- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Metabolomics and Mass Spectrometry Studies
- Microplastics and Plastic Pollution
- Remote Sensing in Agriculture
- Graphene and Nanomaterials Applications
- Invertebrate Immune Response Mechanisms
- Free Radicals and Antioxidants
- Aquaculture disease management and microbiota
- Nanoparticles: synthesis and applications
- Heavy Metal Exposure and Toxicity
- Antimicrobial Peptides and Activities
- Pharmaceutical and Antibiotic Environmental Impacts
- Marine Bivalve and Aquaculture Studies
- Metallurgy and Material Forming
- Recycling and Waste Management Techniques
- Mercury impact and mitigation studies
- interferon and immune responses
- Cell death mechanisms and regulation
- Bioinformatics and Genomic Networks
- biodegradable polymer synthesis and properties
- Remote Sensing and LiDAR Applications
- Pharmacogenetics and Drug Metabolism
Chinese Academy of Sciences
2016-2025
Yantai Institute of Coastal Zone Research
2016-2025
Beijing Electronic Science and Technology Institute
2025
Sichuan University
2024
West China Hospital of Sichuan University
2024
First Affiliated Hospital of Jiangxi Medical College
2024
Nanchang University
2014-2024
Institute of Oceanology
2006-2024
Inner Mongolia Agricultural University
2013-2024
Southern Medical University
2009-2024
Hydroxylated polybrominated diphenyl ethers (HO-PBDEs) may disrupt thyroid hormone status because of their structural similarity to hormone. However, the molecular mechanisms interactions with receptors (TRs) are not fully understood.We investigated between HO-PBDEs and TRbeta identify critical features physicochemical properties related activity, develop quantitative structure-activity relationship (QSAR) models for activity HO-PBDEs.We used recombinant two-hybrid yeast assay determine...
The prokaryotic CRISPR/Cas9 system has recently emerged as a powerful tool for genome editing in mammalian cells with the potential to bring curative therapies patients genetic diseases. However, efficient vivo delivery of this machinery and indeed very feasibility using these techniques remain challenging most tissue types. Here, we show that nonreplicable Cas9/sgRNA ribonucleoproteins can be used correct defects skin stem postnatal recessive dystrophic epidermolysis bullosa (RDEB) mice. We...
One of the problems optical remote sensing crop above-ground biomass (AGB) is that vegetation indices (VIs) often saturate from middle to late growth stages. This study focuses on combining VIs acquired by a consumer-grade multiple-spectral UAV and machine learning regression techniques (i) determine optimal time window for AGB estimation winter wheat (ii) combination multi-spectral algorithms. UAV-based data manually measured wheat, under five nitrogen rates, were obtained jointing stage...
Spectral indices rarely show consistency in estimating crop traits across growth stages; thus, it is critical to simultaneously evaluate a group of spectral variables and select the most informative for retrieving traits. The objective this study was explore optimal predictors above-ground biomass (AGB) by applying Random Forest (RF) on three types predictors: full spectrum, published (Pub-SIs), optimized (Opt-SIs). Canopy hyperspectral reflectance potato plants, treated with seven nitrogen...
Sterols are vital structural and regulatory components in eukaryotic cells; however, their biosynthetic pathways functional roles microalgae remain poorly understood. In the oleaginous microalga Nannochloropsis oceanica, sterol pathway produces phytosterols as minor products cholesterol major product. The evidence together with deduced suggests that N. oceanica exhibits features of both higher plants mammals. Temporal tracking profiles sterol-biosynthetic transcripts response to changes...
Given the tremendous potential for graphene quantum dots (QDs) in biomedical applications, a thorough understanding of interaction these materials with macrophages is essential because are one most important barriers against exogenous particles. Although cytotoxicity and cellular uptake QDs were reported previous studies, between nuclei internalized not well understood. We thus systematically studied nuclear related response associated aminated (AG-QDs) exposure.AG-QDs showed modest 24-h...