- Neonatal Health and Biochemistry
- Viral gastroenteritis research and epidemiology
- Neonatal Respiratory Health Research
- Pediatric Hepatobiliary Diseases and Treatments
- Respiratory viral infections research
- Neuroscience of respiration and sleep
- Metabolism and Genetic Disorders
- Diabetes and associated disorders
- Geriatric Care and Nursing Homes
- Hepatitis B Virus Studies
- Textile materials and evaluations
- Viral Infections and Immunology Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Immunodeficiency and Autoimmune Disorders
- Congenital Diaphragmatic Hernia Studies
- Health disparities and outcomes
- Thermoregulation and physiological responses
- Physical Activity and Health
- Congenital Heart Disease Studies
- Dementia and Cognitive Impairment Research
- Infant Nutrition and Health
- Heme Oxygenase-1 and Carbon Monoxide
- Intestinal Malrotation and Obstruction Disorders
- Diabetes Management and Research
- Thyroid Disorders and Treatments
Chinese University of Hong Kong
1971-2023
Hong Kong Metropolitan University
2015-2018
National Cancer Institute
2009-2012
University of California, San Francisco
2002-2012
National Institutes of Health
2012
Center for Cancer Research
2009
Prince of Wales Hospital
2009
Alice Ho Miu Ling Nethersole Hospital
2008
University of Hong Kong
1992-2007
Queen Mary Hospital
1988-2006
There are limited systematic data on the incidence, clinical characteristics and outcomes of congestive heart failure (CHF) in patients with hyperthyroidism. The aim this study was to investigate outcome CHF as initial presentation primary hyperthyroidism.The prevalence, studied 591 consecutive (mean (SD) age 45 (1) years, 140 men) who presented hyperthyroidism.CHF presenting condition 34 (5.8%) presence atrial fibrillation at (OR 37.4, 95% CI 9.72 144.0, p<0.001) an independent predictor...
Purpose: Researchers often use the term "successful aging" to mean freedom from disability, yet perspectives of elders living with late-life disability have not been well described. The purpose this study was explore meaning successful aging among a diverse sample community-dwelling disability. Design and Methods: Using qualitative grounded theory methodology, we interviewed 56 African American, White, Cantonese-speaking Chinese, Spanish-speaking Latino disabled who participate in On Lok...
Objective. Meconium aspiration syndrome (MAS) is a major cause of respiratory morbidity and mortality in term infants. We reported our pilot experience on the use diluted bovine lung surfactant lipid extract solution (Survanta [Ross Laboratories, Ohio, USA]) as tracheobronchial lavage fluid for treatment infants with severe MAS. Our goal was to establish safety effectiveness this procedure before organizing randomized controlled trial. Method. Six MAS necessitating mechanical ventilation an...
The age-related prevalence of antibodies to herpesviruses was compared in England and Hong Kong. Altogether 327 sera from 266 Kong were tested for herpes simplex virus (HSV), varicella-zoster (VZV), Epstein-Barr (EBV), cytomegalovirus (CMV), human herpesvirus 6 (HHV-6). Herpesvirus infections common both countries but generally acquired earlier more prevalent Over 90% children infected with VZV, EBV, HHV-6 by 8 years age. HSV CMV the least childhood countries, although, 30-40% babies became...
Prostate cancer (PCa), the second most common in men, demands effective early detection strategies. Elevated spermine levels prostate tissue contrast with decreased urinary concentrations PCa patients. Here, we present a novel sensing platform combining differential pulse voltammetry and an extended gate field-effect transistor (EGFET) molecularly imprinted polymer|molecular imprinting (MIP) nanofilm for selective sensitive detection. Key advancements include successfully constructing...
Glutathione (GSH), GSH peroxidase (GPX), reductase (GRD), superoxide dismutase (SOD) and catalase-like enzyme activity were quantified in seminal plasma from normozoospermic patients, men with known distal ductal occlusion, proven fathers male partners of couples receiving in-vitro fertilization (IVF) treatment for both female causes. was non-detectable (< 2.5 microM) plasma. None the activities per unit volume lower semen vasectomized men, suggesting that they did not originate...
Summary. The study was designed to identify those pregnant women who are diagnosed as having gestational diabetes by National Diabetes Data Group (NDDG) criteria, but normal glucose tolerance (NGT) or impaired (IGT) the World Health Organization (WHO) and test whether treatment changed perinatal outcome in with NGT IGT. 216 an abnormal 100 g oral (OGTT) using NDDG criteria were subjected a 75 OGTT. Using WHO 111 (51%) had NGT, 98 (45%) IGT 7 (3%) frank mellitus. Those randomized into control...
In a controlled study of phenobarbitone prophylaxis for neonatal hyperbilirubinemia, 133 term infants born group O mothers were divided into three groups. The first consisted 45 control receiving no medication, the second 44 who received 30 mg drug every night an average 2 weeks before delivery, and third given 5 8-hourly 3½ days beginning 6 to 8 hours after birth. serum bilirubin all was assessed daily days. Treated showed significant reduction incidence hyperbilirubinemia mean levels as...
Abstract Background Advance care planning (ACP) is highly relevant for people with early-stage dementia to communicate their preferences serious illness conditions family caregivers before they become mentally incapacitated. Methods A multi-centre, quasi-experimental study was conducted test the feasibility and acceptability of a theory-guided, dyadic ACP intervention (‘Have Say’ programme) among participants dementia–family caregiver dyads. The trial design, procedures, subject recruitment...
Spermatozoa were recovered from three regions of the epididymis six prostatic carcinoma patients. After washing and incubating for 3 h in Ham's F-10 medium, with or without 5 microM A23187 last 30 min, spermatozoa tested vitality by hypotonic swelling permeated methanol to detect acrosome peanut agglutinin. Whereas extent spontaneous reactions was similar all duct, 17 28% corpus cauda epididymidis respectively, responded stimulation but there no efferent ducts. The percentage morphologically...
A mathematical simulation of the perception thermal and moisture sensations is developed using models that describe physical mechanisms heat transfer in fabrics, neurophysiological responses thermoreceptors. psychoneurophysiological relationships identified from experiments. The coolness dampness to touch knitted fabrics are predicted compared with subjective perceptions measured a psychological experiment. experimental results show that, general, between thermoreceptors follow Stevens'...
We determined titers of group A rotavirus common antibodies and neutralizing against serotypes 1 to 4 prototype human (HRV) in cord blood serum specimens obtained from 38 infants at 4-month intervals birth until 2 years age. Nineteen the developed one episode HRV diarrhea each, they were matched by age weight with other 19 infants, who did not develop during follow-up period. estimated incidence rate infection for two groups combined be a minimum 1.34 episodes per infant year, which is 22...
Rotavirus was identified in 256 (28.5%) of 899 hospitalized children with diarrhea during a 12-month period Hong Kong. Fourteen electropherotypes were identified, and the appearance each occurred sequential manner study period. One patient shown to be mixedly infected two prevalent electropherotypes. Sequential stool specimens from another case showed an extra RNA band course diarrheal episode.
Acute lymphoblastic leukemia (ALL) presenting with bone pain and leukopenia is a recognized clinicopathological complex. Three patients ALL presented back as the major symptom. These cases, together those previously described in literature, illustrate that delay diagnosis frequently occurs, classic features of disease being uniformly absent. The reasons for etiology are dispute. It would appear, however, if early can be made, then prognosis not impaired.
Allergic rhinitis (AR) is a worldwide health problem with rising prevalence. To enhance the estimation of AR prevalence in epidemiological studies, Score for (SFAR), screening tool, has been developed and widely used. An 8-item SFAR handy, self-administered instrument assessing information on nasal eye symptoms, seasonal increase skin test results, previous diagnoses. This study aimed to adapt Chinese population (CSFAR) validate it by testing its psychometric properties diagnostic...
The application of cross sectional echocardiography and pulsed Doppler ultrasound to the management symptomatic neonates with suspected congenital heart disease was studied in 96 consecutive cases. ability establish a complete accurate diagnosis correct plan evaluated. Sequential segmental analysis data from cardiac catheterisation necropsy identified 536 cardiovascular anomalies. Of anomalies 512 were correctly diagnosed by (sensitivity 95.5%). Seven false positive echocardiographic...
<b>Background:</b> A recently halted clinical trial showed that intensive treatment of type 2 diabetes mellitus was associated with increased mortality. Given the phenotypic heterogeneity diabetes, therapy targeted at insulin status may maximize benefits and minimize harm. <b>Methods:</b> In this longitudinal cohort study, we followed 503 patients who were free cardiovascular disease from 1996 until data on mortality outcomes censored in 2005. Phenotype-targeted defined as use a fasting...