A5088557749- Metabolomics and Mass Spectrometry Studies
- Ginseng Biological Effects and Applications
- Analytical Chemistry and Chromatography
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Natural product bioactivities and synthesis
- Chromatography in Natural Products
- Mass Spectrometry Techniques and Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Drug Transport and Resistance Mechanisms
- RNA modifications and cancer
- Plant biochemistry and biosynthesis
- Radioactive element chemistry and processing
- Analytical chemistry methods development
- Plant-based Medicinal Research
- Autophagy in Disease and Therapy
- Liver Disease Diagnosis and Treatment
- Signaling Pathways in Disease
- Wood and Agarwood Research
- HVDC Systems and Fault Protection
- Phytochemistry and Biological Activities
- Molecular Sensors and Ion Detection
- Berberine and alkaloids research
- Lipid metabolism and biosynthesis
- Essential Oils and Antimicrobial Activity
Zhongshan Hospital
2022-2025
Fudan University
2022-2025
Shanghai University of Traditional Chinese Medicine
2020-2025
State Administration of Traditional Chinese Medicine of the People's Republic of China
2020-2025
Jiangsu University
2025
Affiliated Hospital of Jiangsu University
2025
National Health and Family Planning Commission
2024-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
The First Affiliated Hospital, Sun Yat-sen University
2023-2024
Sun Yat-sen University
2023-2024
A novel carboxyl-functionalized metal-organic framework for highly efficient uranium sorption was prepared through a generic postsynthetic strategy, and this MOF's saturation capacity is found to be as high 314 mg·g-1. The preliminary application illustrated that the grafted free-standing carboxyl groups have notably enhanced of uranyl ions on MIL-101. In addition, we performed molecular dynamics simulation combined with density functional theory calculations investigate insights binding...
We herein present a porphyrinic metal–organic framework (MOF) as highly sensitive fluorescent probe targeting Cu(<sc>ii</sc>) ions with fast response.
RNA-binding proteins play multiple roles in several biological processes. However, the of RBM15—an important protein and a significant regulator RNA methylation—in cardiovascular diseases remain elusive. This study aimed to investigate function RBM15 its fundamental mechanisms myocardial infarction (MI). Methylated immunoprecipitation sequencing was used explore N6-methyladenosine (m6A) difference between MI normal tissues. Our findings showed elevated level m6A MI, transcription profile...
Abstract N 6 -methyladenosine (m A) mRNA modification is the most common internal in eukaryotes, which participates a variety of biological processes. However, role m A methylation regulating autophagy induced by ischemia and hypoxia remains to be widely investigated. Here, we investigated impact METTL3, key methyltransferase, on regulation ischemic hypoxic cardiomyocytes, as well mice following acute myocardial infarction (AMI). METTL3 negatively regulated cardiomyocytes under conditions....
Pyrrolizidine alkaloids (PAs) are naturally occurring plant toxins with significant multi-organ toxicity, especially hepatotoxicity. Accidental consumption of PAs-containing herbal medicines can lead to severe health consequences, emphasizing the need for rapid and effective detection methods ensure medicinal safety. In this study, we developed a novel on-site analytical method using paper capillary spray miniature mass spectrometry (PCS-mini MS), created database containing 34 different PAs...
Oxidized low-density lipoprotein (Ox-LDL)-induced endothelial cell injury plays a crucial role in the pathogenesis of atherosclerosis (AS). Plasma galectin-3 (Gal-3) is elevated inside and drives diverse systemic inflammatory disorders, including cardiovascular diseases. However, exact Gal-3 ox-LDL-mediated remains unclear. This study explores effects on ox-LDL-induced dysfunction underlying molecular mechanisms. In this study, Gal-3, integrin β1, GTP-RhoA blood plaques AS patients were...