A5018940432- Mast cells and histamine
- Electrospun Nanofibers in Biomedical Applications
- Phytochemicals and Antioxidant Activities
- biodegradable polymer synthesis and properties
- Natural product bioactivities and synthesis
- Food Quality and Safety Studies
- 3D Printing in Biomedical Research
- Urticaria and Related Conditions
- RNA Interference and Gene Delivery
- Nerve injury and regeneration
- Spectroscopy Techniques in Biomedical and Chemical Research
- Bone Tissue Engineering Materials
- Hydrogels: synthesis, properties, applications
- Graphene and Nanomaterials Applications
- Titanium Alloys Microstructure and Properties
- Radiation Effects and Dosimetry
- Surface Treatment and Coatings
- Blood properties and coagulation
- Electromagnetic Fields and Biological Effects
- Cervical Cancer and HPV Research
- Food Allergy and Anaphylaxis Research
- Lipid metabolism and biosynthesis
- Antioxidant Activity and Oxidative Stress
- T-cell and Retrovirus Studies
- Biotin and Related Studies
Lodz University of Technology
2012-2022
University of Łódź
2007-2018
Łukasiewicz Research Network - Institute for Engineering of Polymer Materials and Dyes
2016
Institute of Spectroscopy
2015
Medical University of Lodz
1998-2000
We have studied live non-malignant (MCF10A), mildly malignant (MCF7) and (MDA-MB-231) breast cancer cells human tissue. demonstrate the first application of Raman imaging spectroscopy in diagnosing role lipid droplets cell line cultures that closely mimic an vivo environment various stages analyzed composition epithelial lines discussed potential as a prognostic marker cancer. To identify any difference droplet-associated biochemistry to correlate it with different cancer, PCA method was...
This paper examines epigenetic changes in breast cancer by Raman imaging, fluorescence AFM and SNOM discusses how they contribute to different aspects of tumourigenesis malignant human epithelial cell lines MCF7 MDA-MB-231 compared with non-malignant MCF10A lines. The focuses on information that can be extracted from microscopy imaging for the biological material nucleoli contained within nucleus lipid droplets cytoplasm. biochemical composition nuclei has been monitored. potential...
Epidemiological studies indicate a high risk of stroke, heart failure and myocardial infarction in patients with multiple sclerosis, especially its secondary progressive (SPMS) phase. Some ischaemic events are directly associated abnormal platelet functions their prothrombotic activity. Recent reports, including this study, confirm the increased activation circulating platelets SPMS, also show reactivity, among other responses, as well strong aggregation. In current we conducted comparative...
ObjectivesRadioprotective potential of quercetin, a powerful free radical scavenger, was investigated in human red blood cells (RBCs) and isolated RBC membranes exposed to γ-irradiation-induced oxidative stress.MethodsRBCs membrane suspensions were irradiated (50 Gy) the presence quercetin (2–50 µM). Oxidative damage analysed by protein carbonyl measurement (enzyme-linked immunosorbent assay). In RBCs, concentration glutathione (GSH) determined. Lipid peroxidation for comparison plasma...
Abstract Biodegradable polymers of poly(lactic acid) (PLLA) and synthesized in‐house poly(trimethylene carbonate) (PTMC) with admixture water‐soluble methyl cellulose (MC) were used for development nerve guidance tubes peripheral nervous system regeneration after injury. Fabrication method involved phase separation viscous dixane solution mixture seat on a rod in proper nonsolvent, which resulted tubular structure large porosity. Influence electron beam sterilization molecular weight,...
Biocompatibility of modified bionanocellulose (BC) and porous poly(ϵ caprolactone) (PCL) were compared to UHMWPE. For all the materials lack cytotoxic effect mouse fibroblasts was observed in vitro. In vivo study, subcutaneous implantations Wistar rats, lasted for seven, 14, 30 days. Subsequently composition surrounding tissue explants surface changes evaluated. No symptoms acute inflammation observed. Surrounding thickness, number granulocytes, lymphocytes, macrophages, blood vessels...
This paper describes the results of radiation-induced crosslinking polysaccharides modified with hydroxypropyl and carboxymethyl functional groups, hydroxypropylcellulose (HPC) carboxymethylcellulose (CMC), respectively, without poly(ethylene glycol) diacrylate (PEGDA) as a agent, to obtain dual stimuli-responsive hydrogels. The gels were characterized in terms water uptake gel fraction, parameters that mainly depend on HPC–CMC compositions, but also macromer crosslinker content absorbed...
Abstract A polymer‐based preparation (a chitosan–microgel called CHM), intended for use as a diet supplement reducing fat and cholesterol absorption from the digestive tract, was obtained by combination of chitosan reduced molecular weight with polyvinylpyrrolidone microgel in 1 : (w/w) ratio. Both components were ionizing radiation (controlled degradation solid state crosslinking polymerization neat vinylpyrrolidone). The component shown previous vitro studies to exhibit high fat‐binding...
It is well known that in some conditions bacteria of physiological flora gastrointestinal tract may become pathogenic. Each complaint which causes injury wall integrity permits to penetrate the tissues and affect tissue cells. Since mast cells represent one very important numerous cellular elements walls, can exert effects on them. Therefore, aim our study was examine influence four strains intestinal mucosa-associated bacteria--Bacteroides thetaiotaomicron, Bacteroides fragilis,...