A5044311542- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Mental Health Research Topics
- Neuroscience and Music Perception
- Schizophrenia research and treatment
- Advanced Neuroimaging Techniques and Applications
- Mental Health Treatment and Access
- Autism Spectrum Disorder Research
- Suicide and Self-Harm Studies
- Face Recognition and Perception
- Neural and Behavioral Psychology Studies
- Palliative Care and End-of-Life Issues
- Language Development and Disorders
- Machine Learning in Healthcare
- Political Philosophy and Ethics
- Ethics in medical practice
- Mental Health and Patient Involvement
- Hearing Loss and Rehabilitation
- Patient Dignity and Privacy
- Digital Mental Health Interventions
- Psychosomatic Disorders and Their Treatments
University of Michigan–Ann Arbor
2018-2022
Mayo Clinic
2021
New York Psychoanalytic Society and Institute
2018
Columbia University Irving Medical Center
2017-2018
New York State Psychiatric Institute
2018
Columbia University
2015-2016
Language and speech are the primary source of data for psychiatrists to diagnose treat mental disorders. In psychosis, very structure language can be disturbed, including semantic coherence (e.g., derailment tangentiality) syntactic complexity concreteness). Subtle disturbances in evident schizophrenia even prior first psychosis onset, during prodromal stages. Using computer-based natural processing analyses, we previously showed that, among English-speaking clinical ultra) high-risk youths,...
Background. Schizophrenia is characterized by profound and disabling deficits in the ability to recognize emotion facial expression tone of voice. Although these are well documented established schizophrenia using recently validated tasks, their predictive utility at-risk populations has not been formally evaluated. Method. The Penn Emotion Recognition Discrimination developed measures auditory recognition, were administered 49 clinical high-risk subjects prospectively followed for 2 years...
Visual processing and attention deficits are responsible for a substantial portion of the disability caused by schizophrenia, but source these remains unclear. In 35 schizophrenia patients (SzP) 34 healthy controls (HC), we used rapid serial visual presentation (RSVP) search task designed to activate/deactivate cortical components attentional control system (i.e. dorsal ventral networks, lateral prefrontal regions in frontoparietal network, cingulo-opercular/salience networks), along with...
Schizophrenia is associated with marked impairments in social cognition. However, the neural correlates of these deficits remain unclear. Here we use naturalistic stimuli to examine role right temporoparietal junction/posterior superior temporal sulcus (TPJ-pSTS)-an integrative hub for cortical networks pertinent understanding complex situations-in inference, a key component cognition, schizophrenia. Twenty-seven schizophrenia participants and 21 healthy control subjects watched clip film...
We characterized peer support specialists' self-disclosures related to suicide and recipient responses inform services for high-risk individuals that may include support.We used an inductive approach thematic analysis identify themes from audio recordings of initial sessions between specialists trained in suicide-related self-disclosure 10 study participants who were admitted inpatient psychiatry units with suicidal ideation or a attempt.The first theme, "I've been suicidal, but those...
Efficient processing of complex and dynamic social scenes relies on intact connectivity many underlying cortical areas networks, but how anomalies affect the neural substrates perception remains unknown. Here we measured these relationships using functionally based localization areas, resting-state functional connectivity, movie-watching data.
Language offers a privileged view into the mind; it is basis by which we infer others’ thoughts. Subtle language disturbance evident in schizophrenia prior to psychosis onset, including decreases coherence and complexity, as measured using clinical ratings familial high-risk (CHR) cohorts. Bearden et al previously used manual linguistic analysis of baseline speech transcripts CHR show that illogical referential thinking, poverty content, predict later onset. Then, Bedi automated natural...
The question of whether or not the terminally ill should be granted an institutional right to die rose forefront national consciousness recently, due in large part efforts late Brittany Maynard. Diagnosed with untreatable brain cancer, Maynard decided end her life last fall Oregon, where state law permits physician-assisted suicide.[i] In editorial for CNN, wrote: “having this choice at my has … given me a sense peace during tumultuous time that otherwise would dominated by fear,...
Profound FER deficits exist in Sz, causing social disability, though can be partly remediated with computer-based training. Neurostimulation might augment remediation if critical nodes were identified. We aimed to 1) briefly recapitulate of Sz HV using rTMS rpSTS, 2) identify connectivity patterns rpSTS regressed by FER, and 3) apply TMS fMRI as readout. Nine healthy volunteers had (10 Hz; 500 msec; 110% RMT) or rOFA (counterbalanced; 10/10 system overlay standard MRI) concurrent (1/3...
The ability to search for and detect social cues, such as facial expressions of emotion, is critical the understanding complex dynamic situations. This involves coordinated actions multiple cognitive domains, including face-emotion processing, mentalization, visual attention. Individuals with schizophrenia are generally impaired in cognition, have been shown deficits all these domains. However, whether neural substrates impairments shared or separate remains unclear. One candidate region a...
Abstract Background Efficient processing of complex and dynamic social scenes relies on intact connectivity many underlying cortical areas networks, but how deficits affect this functioning in cognition remains unknown. Here we measure these relationships using functionally based localization areas, resting-state functional connectivity, movie-watching data. Methods In 42 schizophrenia participants (SzP) 41 healthy controls (HC), measured the localized by face-emotion processing,...