A5043878831- Neuroinflammation and Neurodegeneration Mechanisms
- Cancer-related molecular mechanisms research
- Zebrafish Biomedical Research Applications
- Carbon and Quantum Dots Applications
- Advanced Photocatalysis Techniques
- Animal Genetics and Reproduction
- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Circadian rhythm and melatonin
- MicroRNA in disease regulation
- Neurological Disease Mechanisms and Treatments
- Nanomaterials for catalytic reactions
- Phosphorus and nutrient management
- Wnt/β-catenin signaling in development and cancer
- Marine Ecology and Invasive Species
- Lipid metabolism and biosynthesis
- Growth Hormone and Insulin-like Growth Factors
- bioluminescence and chemiluminescence research
- RNA modifications and cancer
- Animal Behavior and Reproduction
- Adipose Tissue and Metabolism
- Gut microbiota and health
- Protist diversity and phylogeny
- Molecular Biology Techniques and Applications
- Silk-based biomaterials and applications
Lanzhou University
2021-2025
Shanghai University
2024
Shenyang Pharmaceutical University
2023
Ministry of Agriculture and Rural Affairs
2021
Karlsruhe Institute of Technology
2018-2021
Institute of Grassland Research
2021
North China Electric Power University
2020
Northwest A&F University
2011-2019
Chinese Academy of Medical Sciences & Peking Union Medical College
2019
Kunming Medical University
2018
The pollutant reactive red 2 was employed to synthesize fluorescent carbon nanodots allowing biological imaging in vitro and vivo .
NiO-NPs exert toxic effects on zebrafish neurobehavior and neurodevelopment through activation of apoptosis ferroptosis.
A key property of the circadian clock is that it reset by light to remain synchronized with day-night cycle. An attractive model explore input in vertebrates zebrafish. Circadian clocks zebrafish peripheral tissues and even zebrafish-derived cell lines are entrainable direct exposure thus providing unique insight into function evolution regulatory pathways. Our previous work has revealed light-induced gene transcription a step entrainment as well enabling more general adaptation cells...
In this work, a hypochlorous acid (HOCl)-responsive prodrug MB-R for diagnosis and therapy of ischemic stroke (IS) was constructed using the near-infrared fluorophore methylene blue linked to riluzole by urea bond. exhibits good biocompatibility, fast response (<1 min), high selectivity toward HOCl. successfully utilized visualize HOCl levels, as well distribution in brains IS mice determine progression disease. Meanwhile, treatment with could reduce cerebral infarction volume improve motor...
With the increasing requirement for phosphorus resources and their shortage in nature, cyclic utilization of organophosphorus pollutants into phosphatic fertilizer might offer a sustainable approach to achieve recycling phosphorus. Herein, we first report selective degradation (such as HEDP glyphosate), via synergistic effect peroxymonosulfate (PMS) sodium percarbonate (SPC), phosphates, which are continually converted by struvite precipitation on continuous‐flow reactor. Quenching...
With the increasing requirement for phosphorus resources and their shortage in nature, cyclic utilization of organophosphorus pollutants into phosphatic fertilizer might offer a sustainable approach to achieve recycling phosphorus. Herein, we first report selective degradation (such as HEDP glyphosate), via synergistic effect peroxymonosulfate (PMS) sodium percarbonate (SPC), phosphates, which are continually converted by struvite precipitation on continuous‐flow reactor. Quenching...
Nuclear factor erythroid 2 related (Nrf2) is closely associated with neurodegenerative diseases, and the Nrf2-mediated activation of antioxidant response elements (AREs) brings about validated strategies for treating diseases. Here, we discovered that troglitazone, a clinical medication diabetes mellitus, could serve as Nrf2 activator to rescue neuronal damages both in vitro vivo. The mechanism troglitazone action involves binding kelch-like ECH-associated protein 1 (Keap1) Nrf2. This...
The prodrug-based nanoassemblies offer an alternative to settle the deficiencies of traditional chemotherapy drugs. In this nanosystem, prodrugs typically comprise drug modules, modification and response modules. modules are crucial for facilitating accurate conversion at specific sites. work, we opted differentiated disulfide bonds as construct docetaxel (DTX) prodrug nanoassemblies. Interestingly, a subtle change in leads "U-shaped" rate DTX-prodrug Prodrug with least carbon numbers...
Fibroblast growth factor 5 (FGF5) gene, a member of fibroblast superfamily, plays significant roles in the regulation hair cycle during development mammalian follicles as well skeletal muscle development. In this study, DNA sequencing was used to scan putative SNPs within full-length FGF5 and SNPscan high-throughput technique applied individual genotyping 604 crossbred sheep. 10 were identified gene while five them located intron 1 could be genotyped, namely SNP1 (g. 105914953 G > A), SNP2...