A5007399611- Lung Cancer Treatments and Mutations
- Animal health and immunology
- Catalytic Cross-Coupling Reactions
- Artificial Intelligence in Healthcare
- Synthesis and biological activity
- Cancer-related molecular mechanisms research
- Remote Sensing and Land Use
- Chemical Synthesis and Analysis
- Lipoproteins and Cardiovascular Health
- Colorectal Cancer Screening and Detection
- Traumatic Brain Injury and Neurovascular Disturbances
- Atherosclerosis and Cardiovascular Diseases
- Click Chemistry and Applications
- Phytochemicals and Antioxidant Activities
- Remote Sensing in Agriculture
- Quinazolinone synthesis and applications
- Cardiovascular Disease and Adiposity
- Bladder and Urothelial Cancer Treatments
- Colorectal Cancer Treatments and Studies
- Immune Cell Function and Interaction
- Apelin-related biomedical research
- Cerebrovascular and Carotid Artery Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Medical Research and Treatments
- ATP Synthase and ATPases Research
Weihai Municipal Hospital
2015-2024
Shandong University
2020-2024
Beijing Forestry University
2024
Second Affiliated Hospital of Xi'an Jiaotong University
2010-2024
Sun Yat-sen University
2022-2024
Sun Yat-sen University Cancer Center
2022-2024
Liaoning University
2021-2022
Shandong Agricultural University
2022
Jinan University
2014-2021
Guangzhou Vocational College of Science and Technology
2016-2021
Phenolic compounds play important roles in pharmacology, nutrition and inhibition of pathogens. However, there are few studies on the identification phenolic related to walnut anthracnose resistance. In this study, we examined cultivars 'Amigo' 'HuoTe', which resistant susceptible (Colletotrichum gloeosporioides), respectively. After inoculation with C. gloeosporioides, overlapping differentially expressed genes 'HuoTe' were mainly enriched compound biosynthesis pathway, chorismate...
A series of (R)-3,4-dihydroxyphenyllactic acid Danshensu (DSS) derivatives were synthesized, and their cardioprotective effects evaluated in vitro vivo. Among the new derivatives, compound 14 showed significant protective cultured myocardial cells rat model ischemia. The therapeutic efficacy was significantly higher than that its parent DSS, amlodipine, a first-line treatment for angina pain. Compound potently scavenged free radicals, decreased levels LDH MDA, inhibited leakage CK animal We...
The aim of the present study was to investigate therapeutic effect chlorogenic acid on hormonal femoral head necrosis and its protection osteoblasts. established a model in Wistar rats using Escherichia coli endotoxin prednisolone acetate. were divided into five groups treated with different concentrations (1, 10 20 mg/kg). main detected indicators blood rheology, bone mineral density, hydroxyproline hexosamine (HOM) contents. At cellular level, osteoblasts cultured by drug-containing serum....
Abstract Lung cancer is a leading cause of deaths and imposes an enormous economic burden on patients. It important to develop accurate risk assessment model determine the appropriate treatment for patients after initial lung diagnosis. The Cox proportional hazards mainly employed in survival analysis. However, real-world medical data are usually incomplete, posing great challenge application this model. Commonly used imputation methods cannot achieve sufficient accuracy when missing, so we...
Natural marine products are useful candidates for the treatment of oxidative and inflammatory diseases, including myocardial ischemia. 3-bromo-4,5 -dihydroxybenzaldehyde (BDB), a natural bromophenol isolated from red algae, has been shown to display anti-microbial, anti-oxidative, anti-cancer, anti-inflammatory, free radical scavenging activities. In this study, potential protective effects BDB against ischemia reperfusion (IR) injury was investigated in an vitro model mimicked by oxygen...
Abstract Myocardial infarction (MI) is indicated by the symptoms like sharp chest pain, sweating, palpitations, and nervousness finally leading to heart attack. MI occurs mainly due risk factors smoking, elevated blood pressure, diabetes, hypercholesterolemia, obesity, decreased HDL level, LDL hyperlipoproteinemia aging consequently leads demandable coronary supply, oxidative stress, acute necrosis of myocardium. Cardioprotective potential phloroglucinol (PG) was assessed treating...
This work evaluates solid lipid nanoparticles of thiopental sodium against obesity-induced cardiac dysfunction and hypertrophy explores the possible mechanism action. TS loaded SLNs were formulated by hot-homogenization solvent diffusion method. TS-SLNs scrutinized for entrapment efficiency, drug loading capacity, gastric stability, particle size, in vitro release. Mice feed with normal chow or high-fat diet 08 weeks to induce obesity primary cardiomyocytes. The therapeutic effects high fat...
Elevated serum levels of high-sensitive C-reactive protein (hs-CRP) and total cholesterol (TC) correlate with atherosclerotic vascular disease increased frequency events. In this study, we investigated the effect atorvastatin treatment on hs-CRP TC levels, recurrence rate atrial fibrillation (AF) in patients. Furthermore, a meta-analysis was performed to confirm findings study. A 105 patients AF were recruited including 55 who treated amiodarone (the group) 50 only control group). Patients...
Cu 2+ ‐crosslinked carboxymethylcellulose/diatomite composite beads (Cu II @CMC/DE) were prepared in simple and efficient way using ionic crosslinking techniques. In @CMC/DE beads, diatomite serves as a reinforcing filler, divalent copper cation acts agent. The chemical structure morphology of as‐fabricated well characterized various techniques such ICP, FT‐IR, XRD, SEM, EDS, elemental mapping, TEM, XPS, TGA. exerted superior catalytic performance CuAAC reactions benzyl halides, sodium...
We present a rare case of comorbid relapsed acute myeloid leukemia (AML) with the involvement central nervous system (CNS) and subdural seeding vancomycin-resistant Enterococcusfaecium (VRE). The safety profile, treatment approach pharmacokinetic considerations, evaluation success for bilateral administration daptomycin after hematoma (SDH) are assessed.A 45-year-old male history AML who underwent chemotherapy (induction 7 + 3) was admitted to oncology confirmed by bone marrow biopsy,...
The aim of this study was to investigate the effect ouabain (EO) on myocardial remodeling. Twenty-two adult male Sprague-Dawley rats were randomly divided into two groups: in EO group (n=12) intraperitoneally injected with daily and those control (n=10) physiological saline daily. After 8 weeks sacrificed. ultrastructural changes myocardium observed. expression levels voltage-gated potassium channel 4.2 (KV4.2) detected by real-time quantitative reverse transcription-polymerase chain...
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