A5082481552- Salmonella and Campylobacter epidemiology
- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Viral gastroenteritis research and epidemiology
- Infections and bacterial resistance
- Enterobacteriaceae and Cronobacter Research
- Bacterial biofilms and quorum sensing
- Brucella: diagnosis, epidemiology, treatment
- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Antimicrobial Resistance in Staphylococcus
Malawi-Liverpool-Wellcome Trust Clinical Research Programme
2023-2024
University of Liverpool
2023-2024
Public Health Institute of Malawi
2019-2021
Ministry of Health
2019-2021
Ciprofloxacin is the first-line drug for treating typhoid fever in many countries Africa with a high disease burden, but emergence of non-susceptibility poses challenge to public health programmes. Through enhanced surveillance as part vaccine evaluation, we investigated occurrence and potential determinants ciprofloxacin Blantyre, Malawi.
Non-typhoidal Salmonella (NTS) are a major cause of bloodstream infections amongst children in sub-Saharan Africa. A clear understanding the seroepidemiology and correlates protection for invasive NTS (iNTS) relation to key risk factors (malaria, anaemia, malnutrition) Africa is needed inform strategies disease control including vaccine implementation.
Purpose. Carbapenemase-producing Enterobacteriaceae (CPE) have become a global concern and serious threat to human health due their resistance multiple antibiotics. In this study, we identified characterized CPE for the first time in Malawi, southeastern Africa.Methodology. We investigated possible presence of carbapenemases among collection 200 ceftriaxone-nonsusceptible Gram-negative clinical isolates obtained from five Malawian hospitals between January 2016 December 2017, using both...
Stenotrophomonas maltophilia is a significant opportunistic pathogen that associated with high mortality in immunocompromised individuals. In this study, we describe multidrug-resistant (MDR) S. clinical isolate from Kamuzu Central Hospital (KCH), Lilongwe, Malawi.A ceftriaxone and meropenem nonsusceptible (Sm-MW08), recovered December 2017 at KCH, was referred to the National Microbiology Reference Laboratory for identification. April 2018, identified using MALDI Biotyper mass spectrometry...
Abstract Ciprofloxacin is the first-line drug for treating typhoid fever in many high burden countries Africa, but emergence of non-susceptibility poses a grave challenge to public health programmes. Through enhanced surveillance as part vaccine evaluation, we set out investigate occurrence and determinants ciprofloxacin Blantyre, Malawi. We performed systematic antibiotic prescription two centres Malawi between 01/10/2016 31/10/2019, STRATAA TyVAC studies. Blood culture isolates from study...
<ns4:p><ns4:bold>Background:</ns4:bold> Non-typhoidal Salmonella (NTS) are a major cause of bloodstream infections amongst children in sub-Saharan Africa. A clear understanding the seroepidemiology and correlates protection for invasive NTS (iNTS) relation to key risk factors (malaria, anaemia, malnutrition) Africa is needed inform strategies disease control including vaccine implementation.</ns4:p><ns4:p> <ns4:bold>Methodology: </ns4:bold>The SAiNTS study prospective community cohort with...