- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Function and Risk Factors
- Radiomics and Machine Learning in Medical Imaging
- Viral Infections and Immunology Research
- Atomic and Subatomic Physics Research
- Medical Imaging Techniques and Applications
- Cardiomyopathy and Myosin Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis B Virus Studies
- Clostridium difficile and Clostridium perfringens research
- Intracerebral and Subarachnoid Hemorrhage Research
- Infective Endocarditis Diagnosis and Management
- Medical Device Sterilization and Disinfection
- Bone and Joint Diseases
- Muscle Physiology and Disorders
- Lymphoma Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Orthopedic Infections and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- MRI in cancer diagnosis
- Blood Coagulation and Thrombosis Mechanisms
- Lung Cancer Diagnosis and Treatment
University of Duisburg-Essen
2016-2024
Essen University Hospital
2016-2022
Society of Interventional Radiology
2020
Erwin L. Hahn Institute for Magnetic Resonance Imaging
2017
<h3>BACKGROUND AND PURPOSE:</h3> Detailed insight into the composition of thrombi retrieved from patients with ischemic stroke by mechanical thrombectomy might improve pathophysiologic understanding and therapy. Thus, this study searched for links between histologic thrombus subtypes results. <h3>MATERIALS METHODS:</h3> Thrombi 85 who had undergone acute December 2016 March 2018 were studied retrospectively. examined histologically. Preinterventional imaging features, subtypes,...
Objectives T1 mapping allows quantitative myocardial assessment, but its value in clinical routine remains unclear. We investigated, whether the average native can be used as a diagnostic classifier between healthy and diffuse diseased myocardium. Methods Native was performed 54 persons with hearts 150 patients pathologies (coronary artery disease (CAD): n = 76, acute myocarditis: 19, convalescent 26, hypertrophic cardiomyopathy (HCM): 12, dilated (DCM): 17) at 1.5 Tesla mid-ventricular...
To assess two compressed sensing cine magnetic resonance imaging (MRI) sequences with high spatial or temporal resolution in comparison to a reference steady-state free precession (SSFP) sequence for reliable quantification of left ventricular (LV) volumes.LV short axis stacks breath-hold (SPARSE-SENSE HS: resolution: 40 msec, in-plane 1.0 × mm(2) ) and HT: 11 1.7 SSFP (standard SSFP: were acquired 16 healthy volunteers on 1.5T MR system. LV parameters analyzed semiautomatically twice by one...
Radioembolization for the treatment of hepatocellular carcinoma (HCC) induces liver volume changes referred to as "atrophy-hypertrophy complex". The aim this study was investigate lobar after unilateral radioembolization and search factors associated with hypertrophy untreated lobe.Seventy-five patients were retrospectively evaluated. Inclusion criteria were: (1) right-lobar unresectable HCC, (2) available computed tomography scans before, 1, 3, at least 6 months radioembolization. Baseline...
Background Cardiac magnetic resonance imaging (MRI) relies on correct ECG-gating, which is hindered in arrhythmia. Purpose To examine whether a prototype free-breathing real-time cine sequence using SPARSE-SENSE (SPARSE) improves left ventricular quantification atrial fibrillation. Material and Methods On 1.5T MR system short-axis stacks were acquired of the SPARSE “reference” steady-state free precession (SSFP) with arrhythmia rejection 20 patients Two radiologists independently rated...
Introduction The objective of this study was to assess the diagnostic value integrated 11C- methionine PET/MRI for suspected primary brain tumors, in comparison MRI alone. Material and Methods Forty-eight consecutive patients with tumor were prospectively enrolled an 11C-methionine PET/MRI. Two neuro-radiologists separately evaluated alone data sets regarding most likely diagnosis confidence on a 5-point scale. Reference standard histopathology or follow-up imaging. Results Fifty-one...
Purpose A prerequisite for cardiac MR (CMR) imaging is adequate synchronization of image acquisition with the cycle. Electrocardiogram triggering may be hampered by electromagnetic interferences at high field strength. The purpose this work to evaluate feasibility Doppler ultrasound CMR 7T ultra‐high‐field MRI. Methods custom‐built (DUS) trigger device was developed. Magnetic resonance compatibility evaluated using E‐ and H‐field probes flip angle maps prior study. Cardiac performed in 13...
Aim: To quantify the frequency of bacterial contamination injected contrast agent/saline solution by an automated injection system, and to evaluate whether usage a novel tube system can reduce it. Methods: For quantification two identical piston pump MRI injectors were used in combination with standard system. 3-5 ml was collected from prior its connection patients' venous cannula 104 consecutive patients. test, reduces contamination, shielded screw connections same samples further 101...
Background Computer-aided diagnosis is increasingly used in radiology and may support not only unexperienced readers but also senior radiologists. It appears promising, especially the sometimes challenging detection of early ischemic changes stroke CT. Purpose To compare new post-processing software prototype Frontier_ASPECTS against two radiologists ASPECTS evaluation. Material Methods Retrospectively, pre-interventional CTs 100 patients, who underwent endovascular revascularization for...
Transarterial chemoembolization (TACE) is currently the standard of care in patients with unresectable hepatocellular carcinoma (HCC), and selective internal radionuclide therapy (SIRT) 90Y microspheres mainly used as an alternative modality considered poor candidates for TACE. Treatment sorafenib recommended option progressive disease after This study aims to evaluate safety efficacy SIRT glass HCC repeated TACE who are not eligible treatment sorafenib. Forty-seven a median three sessions...
This study examined the feasibility of aortic valve planimetry at 7 T ultrahigh field MRI in intraindividual comparison to 3 and 1.5 MRI.Aortic valves eleven healthy volunteers (mean age, 26.4 years) were on a T, MR system using FLASH TrueFISP sequences. Two experienced radiologists evaluated overall image quality, presence artefacts, tissue contrast ratios, identifiability, details opening area (AVOA). Furthermore, AVOA was quantified twice by reader 1 once 2. Correlation analysis between...
In muscular dystrophies, it is not only skeletal muscles that can be affected, but also the myocardium. This cardiac involvement represent a major cause of morbidity and mortality.To investigate in Duchenne (DMD), Becker (BMD), limb girdle dystrophy (LGMD) patients, carriers DMD/BMD by magnetic resonance (CMR) imaging to search for differences pattern involvement.All patients with genetically or histologically proven DMD, BMD, LGMD, confirmed who had undergone CMR at our clinic between...
Background: Recently faster cardiac magnetic resonance (CMR) cine sequences basing on k-t compressed sensing have been developed. Purpose: To compare two CMR sequences-one in breath-hold technique and one during free breathing—with the standard SSFP sequence with respect to regional left ventricular function assessment. Material Methods: Left short-axis stacks of (sparse_HB) breathing (sparse_FB; both spatial resolution, 1.8 × 8 mm3) a (spatial 1.9 were acquired 50 patients 1.5 T MR system....