A5031195939- Career Development and Diversity
- Biomedical and Engineering Education
- Genetics, Bioinformatics, and Biomedical Research
- Diversity and Career in Medicine
- Mentoring and Academic Development
- Research Data Management Practices
- Cellular transport and secretion
- Protein Kinase Regulation and GTPase Signaling
- Education and Critical Thinking Development
- Higher Education Research Studies
- Nerve injury and regeneration
- Effects and risks of endocrine disrupting chemicals
- Educational Strategies and Epistemologies
- Computational Drug Discovery Methods
- Education Methods and Practices
- Phytase and its Applications
- Retinal Development and Disorders
- Drug Transport and Resistance Mechanisms
- Educational Assessment and Pedagogy
- Scientific Computing and Data Management
- Innovations in Educational Methods
- Ion Transport and Channel Regulation
- Innovative Teaching and Learning Methods
- Fermentation and Sensory Analysis
- Signaling Pathways in Disease
Gwinnett College
2013-2024
Georgia Gwinnett College
2013-2024
Southeastern University
2024
American Society for Cell Biology
2017-2021
Spelman College
2000-2013
Princeton University
2013
University of Miami
2002
University of Alabama at Birmingham
1996
Using an affinity resin and photoaffinity label based on phospholipid analogs of inositol 1,3,4,5-tetrakisphosphate (InsP4), we have isolated, characterized, cloned a 46-kDa protein from rat brain, which named centaurin-α. Binding specificity was determined using displacement 1-O-[3H](3-[4-benzoyldihydrocinnamidyl]propyl)-InsP4 labeling. Centaurin-α displayed highest for phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) (IC50 = 120 nM), whereas InsP4, PtdInsP2, InsP3 bound with 5-, 12-,...
ABSTRACT Application of nerve growth factor (NGF) to PC12 cells stimulates a programme physiological changes leading the development sympathetic neuron like phenotype, one aspect which is neuronal morphology characterised by outgrowth neuritic processes. We have investigated role phosphoinositide 3-kinase in NGF-stimulated morphological differentiation through two approaches: firstly, preincubation with wortmannin, reputedly specific inhibitor kinases, completely inhibited initial responses...
Abstract Whole-genome sequencing, particularly in fungi, has progressed at a tremendous rate. More difficult, however, is experimental testing of the inferences about gene function that can be drawn from comparative sequence analysis alone. We present genome-wide functional characterization sequenced but experimentally understudied budding yeast, Saccharomyces bayanus var. uvarum (henceforth referred to as S. bayanus), allowing us map changes over 20 million years separate this organism...
Promoting diversity and inclusiveness in the STEM academic workforce remains a key challenge national priority. Scientific societies can play significant role this process through creation implementation of programs to foster diversification, by providing mentoring skills development training that empower scientists from under-represented minority (URM) backgrounds succeed their communities practice. In article, we provide examples challenges met scientific these areas present data American...
This essay compares the approaches that scientific societies in ACCESS meta-organization use to implement and assess travel award programs for URM trainees presents a set of recommendations, including both short- long-term outcomes assessment populations interest specialized programmatic activities coupled programs.
Abstract Objective Educational offerings to fill the bioinformatics knowledge gap are a key component enhancing access and use of health data from All Us Research Program. We developed Train Trainer-based, innovative training series including project-based learning, modular on-demand demonstrations, unstructured tutorial time as model for educational engagement in community. Materials Methods highlight our modules content, with survey informing cycles development creation 6-module...
The All of Us Evenings with Genetics (EwG) Research Program at Baylor College Medicine (BCM), funded to engage research scholars work the data, developed a training curriculum for Researcher Workbench, platform access and analyze data. EwG so that it could teach regardless their skills background in programming languages cloud computing. delivered this first annual Faculty Summit May 2022. was evaluated both during after be improved future training.
The Inclusive Environments and Metrics in Biology Education Research (iEMBER) network is a newly forming national community of practice that engages diversity, equity, inclusion stakeholders interdisciplinary collaborative projects. iEMBER was initiated with incubator funding from the National Science Foundation program for Coordination Networks Undergraduate Education. In June 2017, biology education researchers, social scientists, biologists, policy administrators, all interests inclusion,...
The design of programs in support a strong, diverse, and inclusive scientific workforce academe requires numerous difficult conversations about sensitive topics such as the challenges scientists can face their professional development. Theatre be an interactive effective way to foster discussion around subjects. This article examines implementation benefits strategies different contexts, including getting early career academics professionals talking some situations that women...
ABSTRACT Promoting diversity and inclusiveness in the STEM academic workforce remains a key challenge national priority. Scientific societies can play significant role this process through creation implementation of programs to foster diversification, by providing mentoring skills development training that empower scientists from under-represented minority (URM) backgrounds succeed their communities practice. In article, we provide examples challenges met scientific these areas present data...
CRISPR-Cas9 technology represents a once-in-a-generation advance in molecular biology that allows precise gene editing and has become mainstream technique research. However, as is often the case with new technology, most undergraduate instructors do not have training or support to integrate into their courses. To remedy this, we formed "CRISPR Classroom" Network are facilitating series of workshops mentoring activities designed provide instructors, postdocs, graduate students skills,...
We have developed a cell culture of guinea pig gallbladder epithelial cells with which to study ion transport. When grown on permeable supports, the cultured epithelia transepithelial resistance ( R t ) ∼500 Ω · cm 2 . The origin was further confirmed by immunocytochemical localization cytokeratin. Ionomycin and forskolin increased voltage short-circuit current I sc decreased response ionomycin transient, whereas that sustained. Both were attenuated replacement Cl − and/or HCO 3 Mucosal...
The benzenearsonate, Roxarsone, has been used since 1944 as an antimicrobial, growth-promoting poultry feed additive. USGS and EPA report that Roxarsone (4-hydroxy-3-nitrobenzenearsonate) metabolites, including AHBA (3-amino-4-hydroxybenzenearsonate), contaminate waterways at greater than 1100 tons annually. To assess human impact of these organic arsenic water contaminants, it was important to study their potential absorption. adenocarcinoma cell line, Caco-2, is a model for intestinal We...
Many professional societies utilize travel awards programs to foster inclusion and facilitate the development of underrepresented minority (URM) scientists. All member that participate in Alliance Catalyze Change for Equity STEM Success (ACCESS) do so some degree. Members this meta-organization recently came together share their different approaches URM award program assessment. The practices Biophysical Society (BPS), one ACCESS societies, is used as a case study discuss highlights our...
Understanding and visualizing the cell cycle mitosis is an essential concept of biology. This multi-week lab module has students investigate mechanism action anti-cancer drugs that disrupt activities associated with cycle. Students use modern biological techniques such as immunocytochemistry fluorescence microscopy imaging to visualize inner workings mammalian cells determine drug action. Instructors culture fix PtK2 <em>Potorous tridactylis</em> (rat kangaroo) kidney epithelial in 4-well...
The benzenearsonate Roxarsone has been used since the 1960s as an antimicrobial, growth-promoting poultry feed additive. USGS and EPA report that its reduction product, aminohydroxybenzenearsonate (AHBA) are excreted into waterways at greater than two million pounds annually. With a goal of assessing human impact these organic water contaminants, it was important to study their absorption in GI tract. Caco-2 cells model for intestinal absorption. Previously, we found proliferative effect...
One of the major activities any scientific professional society undertakes each year is organizing one or more conferences, at which members can share work and network with others within their discipline. For scientist, attending these regular meetings an important part establishing maintaining a connection to community practice for chosen field study. Though there typically emphasis on providing participants venue present research findings, interaction key motivation conference (1). In...