A5102644495- Microbial Natural Products and Biosynthesis
- Cancer, Lipids, and Metabolism
- Computational Fluid Dynamics and Aerodynamics
- Animal Nutrition and Physiology
- Cavitation Phenomena in Pumps
- Genetic and Environmental Crop Studies
- Hemoglobinopathies and Related Disorders
- Genetic diversity and population structure
- Ubiquitin and proteasome pathways
- Chemotherapy-induced cardiotoxicity and mitigation
- Autophagy in Disease and Therapy
- Plant Genetic and Mutation Studies
- Renal Transplantation Outcomes and Treatments
- Circular RNAs in diseases
- Iron Metabolism and Disorders
- Genomics and Phylogenetic Studies
- Effects of Environmental Stressors on Livestock
- Turbomachinery Performance and Optimization
- Ferroptosis and cancer prognosis
- Medicinal Plant Research
- Microbial Community Ecology and Physiology
- Essential Oils and Antimicrobial Activity
- Hearing, Cochlea, Tinnitus, Genetics
- Carbon Nanotubes in Composites
- T-cell and B-cell Immunology
Kunming University of Science and Technology
2024-2025
First People's Hospital of Yunnan Province
2024-2025
Inner Mongolia University
2023-2024
Xi'an Jiaotong University
2012-2022
First Hospital of Jilin University
2002
Jilin University
2002
Coronary artery calcification (CAC) is a common complication in patients with stable ischemic heart disease (SIHD). However, the early diagnosis and understanding of pathogenesis CAC SIHD remain underdeveloped. This study aimed to analyze aberrant alterations serum proteome patients, as well severe (CAC_SIHD), explore potential risk factors patients. Serum proteomic profiles were obtained from individuals (n = 6), CAC_SIHD healthy controls 9), analyzed using nano liquid chromatography tandem...
Recently, increasing attention has been paid to the role of Squalene epoxidase (SQLE) in several types cancers. However, its functional tumor progression head and neck squamous cell carcinoma (HNSCC) is still unclear. We performed bioinformatic analyses relative experiments assess potential mechanism SQLE-mediated HNSCC malignancy. And results showed that SQLE was significantly upregulated samples compared with peritumor samples. Mechanistically, miR-584-5p downregulation may lead...
This research investigates the flavonoid biosynthesis pathways of two ecotypes Leymus chinensis, distinguished by their gray-green (GG) and yellow-green (YG) leaf colors, to uncover molecular bases adaptability different environmental conditions. By integrating comprehensive transcriptomic metabolomic analyses, we identified 338 metabolites, with 161 showing differential expression—124 upregulated 37 downregulated. The data revealed substantial variation, 50,065 genes differentially...
Doxorubicin (DOX) is an extensively used chemotherapeutic agent that induces cardiotoxicity. Studies have reported exercise (EXE) can alleviate DOX-induced Therefore, this study aimed to explore the mechanism by which EXE attenuates myocardial injury.
Activation-induced cytidine deaminase (AID) initiates somatic hypermutation and class switch recombination of immunoglobulin genes in B cells, whereas off-targeted AID activity contributes to oncogenic mutations chromosomal translocations associated with cell malignancies. Paradoxically, only a minority is allowed access the nuclear genome, but majority retained cytoplasm. It unknown whether cytoplasmic can target mitochondrial genome [mitochondrial DNA (mtDNA)]. To address this issue, we...
Intraorganismal genetic heterogeneity (IGH) exists when an individual organism harbors more than one genotype among its cells. In general, intercellular DNA diversity occurs at a very low frequency and cannot be directly detected by sequencing from bulk tissue. this study, based on Sanger high-throughput sequencing, different species, organs, segments single cell were employed to characterize nucleotide mutations in Leymus chinensis. The results demonstrated that 1) the nuclear showed...