Haikuan Wang

ORCID: 0000-0001-7548-6146
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About
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Research Areas
  • Enzyme Catalysis and Immobilization
  • Microbial Metabolic Engineering and Bioproduction
  • Electrochemical sensors and biosensors
  • Probiotics and Fermented Foods
  • Microbial Metabolites in Food Biotechnology
  • Food composition and properties
  • Visual Attention and Saliency Detection
  • Enzyme-mediated dye degradation
  • Enzyme Production and Characterization
  • RNA and protein synthesis mechanisms
  • Advanced Neural Network Applications
  • Educational Robotics and Engineering
  • Spinal Fractures and Fixation Techniques
  • Spine and Intervertebral Disc Pathology
  • Genomics and Phylogenetic Studies
  • Seed and Plant Biochemistry
  • Video Surveillance and Tracking Methods
  • Microbial Community Ecology and Physiology
  • Protein Structure and Dynamics
  • Engine and Fuel Emissions
  • Peptidase Inhibition and Analysis
  • Biocrusts and Microbial Ecology
  • Antimicrobial Peptides and Activities
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Educational Reforms and Innovations

Guangzhou University of Chinese Medicine
2016-2025

Tianjin University of Science and Technology
2007-2024

Shanghai University
2024

Tianjin Economic-Technological Development Area
2019

Peking University
2017

Tianjin University of Technology
2010

Ministry of Education of the People's Republic of China
2007

While the Lenke classification enhances our structural understanding of adolescent idiopathic scoliosis (AIS), biomechanical implications for spinal range motion (ROM) and intervertebral disc (IVD) loadings remain unclear. This study aims to quantitatively explore compare these responses in normal thoracolumbar spines those with various curvatures types under pure bending conditions. The baseline finite element (FE) model was derived from a comprehensive human body FE model, validated,...

10.3389/fbioe.2025.1473776 article EN cc-by Frontiers in Bioengineering and Biotechnology 2025-02-19

ABSTRACT Understanding how bacteria coordinate growth with cell cycle events to maintain size homeostasis remains a grand challenge in biology. The period of chromosome replication (C period) is key stage the bacterial cycle. However, mechanism vivo regulation C unclear. In this study, we found that titration expression ribonucleotide reductase (RNR), which changes intracellular deoxynucleoside triphosphate (dNTP) pools, enables significant perturbations period, leading substantial change...

10.1128/mbio.01741-17 article EN cc-by mBio 2017-11-15

Diabetes is a chronic metabolic disease characterized by hyperglycaemia and number of potential complications that significantly reduce the patient's quality life. In this study, we produced an antidiabetic functional food from Tartary buckwheat fermented Lactobacillus plantarum TK9 L. paracasei TK1501. The results orthogonal experimental design indicated three factors with largest effects on growth TK1501 in solid-state fermentation (SSF) were order: water ratio>inoculum size>time...

10.17113/ftb.56.03.18.5540 article EN cc-by Food Technology and Biotechnology 2018-01-01

In vitro fermentation of six functional oligosaccharides including fructooligosaccharides (FOS), galactooligosaccharides (GOS), xylooligosaccharides (XOS), isomaltooligosaccharides (IMOS), raffinose and stachyose was performed by using Clostridium butyricum TK2 CB8. Among the oligosaccharides, IMOS revealed strongest fermentability for both strains, which supported highest viable cells (10.1 ± 1.05 9.8 0.41 log (CFU / mL)) levels SCFA or butyrate (11.77 0.37 14.47 mM) from with this...

10.3136/fstr.20.1005 article EN Food Science and Technology Research 2014-01-01

Cyanobacterial blooms are a global ecological problem. The purpose of this study is to find microbial strains that can be used for the biological control cyanobacterial blooms. In study, strain Lysinibacillus fusiformis (QY-12) with best algae inhibition effect was isolated and screened. rate Microcystis aeruginosa in growth index period 82.01% after 8 days interference by QY-12. algicidal substance l-2-aminoadipic acid (L-2-AA) produced QY-12 purified via preparative HPLC identified nuclear...

10.1021/acsagscitech.3c00251 article EN ACS Agricultural Science & Technology 2024-01-23

Abstract The hydrolysis activities of three alkaline lipases, L-A1, L-A2 and L-A3 secreted by different lipase-producing microorganisms isolated from the Bay Bohai, P. R. China were characterized with 16 kinds esters. It was found that all lipases have ability to catalyze glycerides, methyl esters, ethyl especially for triglycerides, which shows they broad substrate spectra, this property is very important them be used in detergent industry. Three QSAR models built respectively GFA using...

10.1186/1476-511x-11-124 article EN cc-by Lipids in Health and Disease 2012-09-28

10.1109/iccc62609.2024.10941859 article EN 2021 7th International Conference on Computer and Communications (ICCC) 2024-12-13

To improve the proteolytic stability of lipase LIP2 from Yarrowia lipolytica, peptide bonds susceptible to trypsin in were analyzed by tandem mass spectrometry and redesigned site-directed mutagenesis. Different variants enzyme expressed Pichia pastoris GS115 their biochemical properties subsequently investigated. Although most still cleaved trypsin, some them did show an evident increase resistance against degradation. The stable mutant was LIP2-C5, which five trypsin-cleavage sites...

10.1093/protein/gzaa001 article EN Protein Engineering Design and Selection 2019-08-01

Clostridium butyricum is a widely utilized probiotics, also used as an alternative to antibiotics for humans and growth promotion in wide variety of livestock species. The objective this study is develop economical practical fermentation medium the of C. butyricum TK2 using orthogonal test. optimal was obtained by single factor test carbon source, nitrogen source factors design. estimated be most formula (per liter): 8 g glucose, 20 soybean meal (hydrolyzed 3 h neutral protease), 5 brewer’s...

10.5897/ajmr10.789 article EN African Journal of Microbiology Research 2011-07-18

A newly isolated moderate thermophilic strain 1-7 producing alkaline and thermostable lipase previously was identified as Acinetobacter calcoaceticus, which from the soil collected bay of Bohai in China. The showed maximum activity at pH 9.0 high thermostability. calcoaceticus purified by ammonium sulfate precipitation, ion exchange chromatography Sephadex G-75 chromatography. molecular mass (Mr) estimated to be 30 kDa using SDS-PAGE.

10.1109/icbbe.2010.5517247 article EN International Conference on Bioinformatics and Biomedical Engineering 2010-06-01

Surveys show that less than one tenth of graduates in acupuncture and massage major from colleges traditional Chinese medicine are proficient therapy.The basic reason is most majors haven't do enough practice to lay a solid foundation, or unable stand high-duty because low fatigue durability due weak physical ability have abandon massage.In view this, it suggested optimize the mode techniques course teaching perspective objectives, contents, installation, examination evaluation, etc.,...

10.2991/ssehr-16.2016.119 article EN cc-by-nc 2016-01-01

During recent years, with the increase of material living standard, people have paid more and attention to physical conditions.Thus massage manipulation teaching which can impose certain impact on people's health has also gradually attracted wide attention.Especially during 10-year integral moving Guangzhou Higher Education Mega Center, our university developed Massage Manipulation-interscholastic course Center.To give lecture well among those students having no medical foundation let them...

10.2991/ieesasm-16.2016.82 article EN cc-by-nc Proceedings of the 2017 5th International Education, Economics, Social Science, Arts, Sports and Management Engineering Conference (IEESASM 2017) 2016-01-01

The acroparalysis left after stroke is the main factor affecting patients' activities of daily living, so limb rehabilitation training particularly important for patients.The modern western medical dominated by active movement and patients are easy to have fatigue inimical emotions during training; however, traditional Chinese massage, which passive movement, can make up discomfort caused movement.Therefore, it required explore a more effective treatment method apoplectic hemiplegia...

10.2991/essaeme-16.2016.24 article EN cc-by-nc 2016-01-01
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