A5024217912- Antibiotic Resistance in Bacteria
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Antibiotic Use and Resistance
- Vibrio bacteria research studies
- Bacterial Identification and Susceptibility Testing
- Diagnosis and treatment of tuberculosis
- Antifungal resistance and susceptibility
- Spondyloarthritis Studies and Treatments
- Bacterial biofilms and quorum sensing
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Antibiotics Pharmacokinetics and Efficacy
- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Enzyme Catalysis and Immobilization
- Acne and Rosacea Treatments and Effects
- Pneumonia and Respiratory Infections
- Liver Disease Diagnosis and Treatment
- Infectious Diseases and Tuberculosis
- Adrenal Hormones and Disorders
- Salmonella and Campylobacter epidemiology
- Nail Diseases and Treatments
Bangabandhu Sheikh Mujib Medical University
2015-2024
American University in Cairo
2023
International Centre for Diarrhoeal Disease Research
2022
Universitas Ibrahimy
2022
Ibrahim Cardiac Hospital & Research Institute
2022
Universiti Malaysia Sarawak
2008-2021
Benha University
2020
Ahmadu Bello University
2019
Al-Azhar University
2018
Zagazig University
2017
A recombinant Saccharomyces cerevisiae strain transformed with xylose reductase (XR) and xylitol dehydrogenase (XDH) genes from Pichia stipitis (PsXR PsXDH, respectively) has the ability to convert ethanol together unfavourable excretion of xylitol, which may be due intercellular redox imbalance caused by different coenzyme specificity between NADPH-preferring XR NAD+-dependent XDH. In this study, we focused on effect(s) mutated NADH-preferring PsXR in fermentation. The R276H K270R/N272D...
A 27-year-old man with double-outlet right ventricle, status post-Fontan operation, presented acute stroke after recent diagnosis of a ventricular thrombus. While hospitalized, he developed worsening hypoxemia secondary to pulmonary embolism. This case highlights interdisciplinary management patients single-ventricle physiology and anticoagulation in Fontan patients.
Increasing evidence of carbapenem-resistant Pseudomonas aeruginosa (CRPA) infection in healthcare facilities poses an alarming threat to public health. There is little on the occurrence this organism Bangladeshi hospitals.We collected 117 environmental swab samples from two tertiary care hospitals Dhaka, Bangladesh and tested for species by nonselective enrichment swabs followed plating Cetrimide agar. We confirmed isolates as P. API 20NE test polymerase chain reaction Polymerase Chain...
We focused on the effects of a mutation xylose reductase from Pichia stipitis (PsXR) xylose-to-ethanol fermentation using recombinant Saccharomyces cerevisiae transformed with PsXR and PsXDH (xylitol dehydrogenase P. stipitis) genes. Based inherent NADH-preferring XR several site-directed mutagenetic studies other aldo-keto enzymes, we designed single mutants. K270R showing decreased NADPH-preferring activity without change in was found to be potent mutant. Strain Y-K270R wild-type showed...
The physiochemical properties of biodiesel are significantly influenced by its fatty acid composition (FAC). This research investigates FAC Jatropha (JB) synthesized using feedstocks originated from the east (JBEM) and west (JBWM) Malaysian regions together with biofuel properties. critical pure biodiesels blends were analysed according to ASTM D6751/EN 14214 standards. JB precisely regulated features such as saturated acids (SFAs), unsaturated (USFAs), degree unsaturation, long chain...
Evaluating the serum levels of IP-10, MCP-1, MIP-1α, and IL-6 genotyping rs12252 SNP IFITM3 gene among different categories COVID-19 patients might aid in understanding pathogenesis contribute to developing disease-specific biomarkers therapeutic strategies.This is a cross-sectional study involving total 84 confirmed by positive RT-PCR 28 healthy controls. were recruited from intensive care unit (ICU) COVID Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka. categorized into...
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that involves cytokines in its pathogenesis. This study aimed at investigating if gene polymorphisms like IL-17, IL-4, IL-6, and IL-12 affect RA susceptibility severity the Bangladeshi population. was cross-sectional comparative included 40 diagnosed patients according to American College of Rheumatology (ACR) criteria 2010, who were free from other rheumatological diseases, healthy subjects for comparison. The used...
Total 60 mid stream urine samples were collected from suspected urinary tract infection patients of 1 to 12 years age indoor and outdoor BSMMU. A total 28 (46.66%) cultures yielded significant growth single organism & 32 (53.33%) no growth. E. coli was isolated in 53.57% cases, followed by 17.86% Klebsiella spp, 10.71% Enterococcus 7.14% Enterobacter Pseudomonas aeruginosa 3.5% Proteus mirabilis. less sensitive first line drugs including Amoxycillin, Cotrimoxazole, Cephradin, Nalidexic...
Analyzing antibiotic susceptibility pattern of uropathogens help to overcome the therapeutic difficulties created by rising antimicrobial resistant bacteria and guides in choosing appropriate antibiotics. Hence, we aimed at evaluating pathogens causing UTI study their antibiogram. Midstream urine samples were collected, cultured biochemical tests performed for proper identification urinary BSMMU from January 2013 December 2013. The most common isolated Gram negative Escherichia coli (63.93%)...
In order to monitor changes in the etiologic bacterial agents and as well antimicrobial resistance of urinary pathogens between five years period over several years, culture sensitivity result patients attending outpatient departments Bangabandhu Sheikh Mujib Medical University (BSMMU) 2003 2008 were analyzed retrospectively. 2008, 668 715 cultures respectively reviewed. The frequency Escherichia coli dropped significantly clinics from 60.02% 51.75%. Klebsiella spp increased considerably....
The present study has been carried out in an attempt to evaluate antimicrobial susceptibility patterns with special reference of Salmonella Typhi ciprofloxacin isolated from blood culture. is also designed find the MIC Ciprofloxacin by E- test. Blood samples were taken for culture sensitivity, Widal test and ICT 100 clinically suspected cases typhoid fever 1st week illness who attended at patient department Rajshahi Medical College Hospital (RMCH).The was done Microbiology Department Shishu...
An in vivo study was carried on rats to see the influence of arsenic aerobic gut flora. A significant inhibition flora observed after 2 weeks administration (1 mg/L) ad libitum with a decrease stool level and increase liver level. However, this inhibitory effect not presence vitamin E mg/day) or selenium (0.4 mg/day). Pretreatment streptomycin (500 mg twice daily) showed similar results. Rats that received folic acid (200 floral count but there were decreased level.Keywords: Aerobic;...
Antinuclear antibody (ANA) is useful in the diagnosis of connective tissue disorder (CTD). Association specific autoantibodies with immunofluorescence pattern ANA CTD, noted western literature has been considered as reference all over world. However, Bangladesh no such research work or data correlating and their patterns found. Objective study was to identify an association between antinuclear on HEp-2 cell more reactivities (e.g. anti-dsDNA anti-extractable nuclear antigen) serum samples...
Dermatophytes are by far the most significant fungi because of their widespread involvement population at large and prevalence all over world. This is an attempt to observe spectrum dermatophytes among clinically suspected cases dermatophytosis attending outpatient department Dermatology Venereology, Bangabandhu Sheik Mujib Medical University, Dhaka. Three hundred twenty were subjected mycological studies. One five (32.8%) positive for fungus in direct microscopy while 97(30.3%) culture...
The antibacterial effects of three mushrooms extract Ganoderma lucidum, Auricularia auricula, Pleurotus florida were studied against Staphylococcus aureus and Escherichia coli. A. auricula showed significant activity S. aureus. P. some while G. lucidum no activity. None the extracts any E.
We applied protein engineering to construct an efficient biomass-ethanol conversion system using Saccharomyces cerevisiae. Intercellular redox imbalance caused by the different coenzyme specificity of xylose reductase (XR) and xylitol dehydrogenase (XDH) has been thought be one main factors excretion. Introduction NADH-dependant XR generated in this study reduced excretion probably because maintaining intercellular balance. Ethanol fermentation was measured batch culture under anaerobic...
Critically ill patients acquire an infection during their stay in intensive care unit (ICU) and the frequency of these infections varies considerably different populations clinical settings. The purpose this study was to know antimicrobial sensitivity pattern Acinetobacter isolates from tracheal aspirate, blood central venous catheter, peripheral blood, urine endotracheal tube admitted ICU at BSMMU(Bangabandhu Sheikh Mujib Medical University) hospital, Dhaka, Bangladesh over a one year...
From May to December 2021, Bangladesh experienced a major surge in the Delta variant of SARS-CoV-2. The earlier rollout several vaccines offered opportunity evaluate vaccine effectiveness against this variant.A prospective, test-negative case-control study was conducted five large hospitals Dhaka between September and 2021. subjects were patients at least 18 years age who presented themselves for care, suffering COVID-like symptoms less than 10 days' duration. cases had PCR-confirmed...