- Advanced Radiotherapy Techniques
- Management of metastatic bone disease
- COVID-19 Clinical Research Studies
- Brain Metastases and Treatment
- SARS-CoV-2 and COVID-19 Research
- Advances in Oncology and Radiotherapy
- Lung Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Global Cancer Incidence and Screening
- Cancer Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Spine and Intervertebral Disc Pathology
- Breast Cancer Treatment Studies
- Global Health and Surgery
- Medical Imaging Techniques and Applications
- Childhood Cancer Survivors' Quality of Life
- Multiple and Secondary Primary Cancers
- Endometrial and Cervical Cancer Treatments
- Cancer Immunotherapy and Biomarkers
- Economic and Financial Impacts of Cancer
- Radiation Therapy and Dosimetry
- COVID-19 epidemiological studies
- Prostate Cancer Treatment and Research
- Chemotherapy-induced organ toxicity mitigation
- Boron Compounds in Chemistry
Showa General Hospital
2022
Dhaka Community Hospital Trust
2020
Philippine General Hospital
2019
COVID-19 caused by SARS-CoV-2 ranges from asymptomatic to severe disease and can cause fatal devastating outcome in many cases. In this study, we have compared the clinical, biochemical immunological parameters across different spectrum of Bangladeshi patients.
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Aim: To define safety and efficacy of a palliative, short-course accelerated radiation therapy for symptomatic locally advanced primary pelvic cancer. Materials Methods: A phase II trial was planned based on the minimax Simon9s two-stage design. total 18 Gy in 4.5 Gy/fraction administered twice day delivered (SHARON). Pain quality life were recorded according to Visual Analogue self-assessment cancer linear analog scales (CLAS), respectively. Results: Twenty-five patients enrolled study. The...
Aim: To determine the maximum tolerated dose (MTD) of a short-course accelerated radiotherapy and its feasibility for symptomatic palliation advanced head neck cancer or metastases from any primary site. Patients Methods: A phase I trial in four dose-escalation steps was planned: total ranged between 14 20 Gy fractions administered twice day. The dose-limiting toxicity (DLT) determined as grade 3 more occurring during treatment. MTD obtained used to plan II trial. Results: 48 patients were...
Coronavirus disease 2019 (COVID-19) is a protean causing different degrees of clinical severity including fatality. In addition to humoral immunity, antigen-specific T cells may play critical role in defining the protective immune response against SARS-CoV-2, virus that causes this disease. As part longitudinal cohort study Bangladesh investigate B and cell-specific responses, we sought evaluate activation-induced marker (AIM) status cell subsets during COVID-19 infection. We analyzed total...
Previous trials showed the tolerability and efficacy of a palliative radiotherapy (RT) regimen (SHARON) based on 4 fractions delivered in 2 days different oncological settings. In order to identify possible predictors symptomatic response, purpose this study is perform pooled analysis previous trials. We analyzed impact response following parameters: tumor site, histological type, performance status (ECOG), dominant symptom, RT dose using Chi-square test Fisher's exact test....
From May to December 2021, Bangladesh experienced a major surge in the Delta variant of SARS-CoV-2. The earlier rollout several vaccines offered opportunity evaluate vaccine effectiveness against this variant.A prospective, test-negative case-control study was conducted five large hospitals Dhaka between September and 2021. subjects were patients at least 18 years age who presented themselves for care, suffering COVID-like symptoms less than 10 days' duration. cases had PCR-confirmed...
The longevity of immune responses induced by different degrees severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection provides information important to understanding protection against disease 2019 (COVID-19). Here, we report the persistence SARS-CoV-2 spike receptor-binding domain (RBD) specific antibodies and memory B cells recognizing this antigen in sequential samples from patients Bangladesh with asymptomatic, mild, moderate COVID-19 out six months following infection....
Abstract Objective: The purpose of this study is to demonstrate the synchronous bilateral breast irradiation radiotherapy technique using a single isocenter. Materials and Methods: Six patients were treated with isocenter from February 2011 June 2016. All underwent CT-simulation appropriate positioning device. Target volumes critical structures like heart, lung, esophagus, thyroid, etc., delineated slice by in CT data. An was placed above sternum on skin both medial tangential lateral /...
Abstract Aim: To compare the dosimetric advantage of stereotactic body radiotherapy (SBRT) for localized lung tumor between deep inspiration breath hold technique and free breathing technique. Materials methods: We retrospectively included ten previously treated patients in this study. All underwent CT simulation using 4D-CT (FB) (DIBH) techniques. Plans were created three coplanar full modulated arc 6 MV flattening filter (FFF) bream with a dose rate 1400 MU/min. Same constraints target...
The present study aimed to provide practical guidelines for palliative treatment of advanced carcinoma the pancreas (CAP) with 2D technique. Fifteen patients locally CAP consecutively treated radiation therapy at Radiation Oncology Center, Research and Care Foundation 'Giovanni Paolo II' (Campobasso, Italy) underwent computed tomography simulation in supine position. Definition clinical target volume (CTV) included head body pancreas, retropancreatic space. planning was defined by adding a...
The purpose of the present study was to propose an optimized 2D technique (2D-conformal) for radiotherapy (RT) pancreatic cancer (CaP). This is based on double simulation which resolves problems radiographic image distortion. Five patients with locally advanced CaP were identified and enrolled. Treatment planning simulated in 3 different ways: Two dimensional-standard (2D-SRT), 2D-conformal (2D-CRT), three dimensional-conformal (3D-CRT) techniques 10 MV LINAC. Simulation a cobalt machine...