- Advanced Radiotherapy Techniques
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Pancreatic and Hepatic Oncology Research
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Glioma Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Advances in Oncology and Radiotherapy
- Lung Cancer Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal and Anal Carcinomas
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiopharmaceutical Chemistry and Applications
- Breast Cancer Treatment Studies
- Sarcoma Diagnosis and Treatment
- Brain Metastases and Treatment
- Head and Neck Cancer Studies
- Cancer Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Ovarian cancer diagnosis and treatment
- Cancer Genomics and Diagnostics
- Microbial Inactivation Methods
University of Bologna
2016-2025
Azienda USL di Bologna
2021-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2023
Mulago Hospital
2012-2022
Policlinico S.Orsola-Malpighi
2015-2020
Centre Léon Bérard
2019
GTx (United States)
2019
March of Dimes
2018
University Medical Center Freiburg
2018
Champalimaud Foundation
2018
Abstract Despite the recent advanced developments in radiation therapy planning, treatment planning for head-neck and pelvic cancers remains challenging due to large concave target volumes, multiple dose prescriptions numerous organs at risk close targets. Inter-institutional studies highlighted that plan quality strongly depends on planner experience skills. Automated optimization of procedure may improve best practice. We performed a comprehensive dosimetric clinical evaluation Pinnacle 3...
Aims This ARISE study secondary analysis aims to delve into the complexities of pain management in breast cancer patients undergoing radiotherapy (RT) Italy. It identify and analyze predictive variables for adequacy establish relationship between these effectiveness control. Materials methods observational engaged 2,104 participants from 13 Italian RT departments, focusing on 426 reporting pain. Advanced statistical methods, were employed significant adequacy. Data collection involved a...
Aim: The purpose of the present multicentric study was to review stereotactic body radiotherapy (SBRT) with or without chemotherapy (CHT) experience in locally advanced pancreatic cancer (LAPC). Endpoints were overall survival (OS), local control (LC), and distant metastasis-free (DMFS). Several parameters9 impact on these outcomes assessed. Materials Methods: Fifty-six patients LAPC undergoing SBRT+/-CHT included. SBRT median BED<sub>α/β10Gy</sub> 48.0 Gy (range=28.0-78.7). Survival curves...
Radiation-induced skin toxicity is a common and distressing side effect of breast radiation therapy (RT). We investigated the use quantitative spectrophotometric markers as input parameters in supervised machine learning models to develop predictive model for acute toxicity.One hundred twenty-nine patients treated adjuvant whole-breast radiotherapy were evaluated. Two spectrophotometer variables, i.e. melanin (IM) erythema (IE) indices, used quantitatively assess physical changes....
Locally advanced cervical cancer represents a significant treatment challenge. Body composition parameters such as body mass index, sarcopenia, and sarcopenic obesity, defined by sarcopenia BMI ≥ 30 kg/m
The aim of this study was to investigate the impact SUVmax fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) measured in primary tumor, pelvic and para-aortic node with disease-free survival (DFS) overall (OS) patients locally advanced cervical cancer.A total 92 histological diagnosis cancer are treated radiochemotherapy plus brachytherapy boost from January 2008 April 2014 our Institution. A pretreatment FDG-PET/CT for staging radiotherapy planning performed,...
Systemic inflammation indices were found to be correlated with therapeutic outcome in several cancers. This study retrospectively analyzes the predictive role of a broad range systemic inflammatory markers patients locally advanced cervical cancer (LACC) including patient-, tumor-, and treatment-related potential prognostic factors. All underwent definitive chemoradiation pretreatment values (neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio, monocyte/lymphocyte immune index...
Background/Aim: To retrospectively evaluate the outcome of patients with unresectable biliary cholangiocarcinoma (CC) treated radiotherapy (RT) plus/minus chemotherapy (CHT). Materials and Methods: Data intrahepatic CC (ICC), Klatskin9s tumor (KT), distal extrahepatic (ECC), gallbladder cancer (GBC) diagnosed from 1991 to 2017 were analyzed. The treatment was mainly based on RT plus concurrent CHT +/− brachytherapy (BRT) boost. Kaplan–Meier method used calculate survival curves that compared...
Aim: To report the outcome of hypofractionated radiotherapy after radical prostatectomy (RP) for prostate cancer (PCa) using simultaneous integrated boost-intensity modulated radiation therapy (SIB-IMRT). Patients and Methods: A total 124 patients with PCa at high risk relapse RP or diagnosis biochemical were included. received 62.5 Gy to bed 45 pelvic nodes in 25 fractions. Androgen-suppressive was prescribed based on National Comprehensive Cancer Network categories. Results: Median...