Polash Chandra Karmakar

ORCID: 0000-0003-1413-9911
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About
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Research Areas
  • Sperm and Testicular Function
  • Effects and risks of endocrine disrupting chemicals
  • Toxic Organic Pollutants Impact
  • Reproductive Biology and Fertility
  • SARS-CoV-2 and COVID-19 Research
  • Microplastics and Plastic Pollution
  • COVID-19 Clinical Research Studies
  • Viral gastroenteritis research and epidemiology
  • Vibrio bacteria research studies
  • Corneal Surgery and Treatments
  • Orthopaedic implants and arthroplasty
  • Periodontal Regeneration and Treatments
  • Bone Tissue Engineering Materials
  • Drug-Induced Hepatotoxicity and Protection
  • Long-Term Effects of COVID-19
  • Influenza Virus Research Studies
  • Ginger and Zingiberaceae research
  • COVID-19 epidemiological studies
  • Wound Healing and Treatments
  • Advances in Cucurbitaceae Research
  • Carcinogens and Genotoxicity Assessment
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Probiotics and Fermented Foods
  • Scientific and Engineering Research Topics
  • Hibiscus Plant Research Studies

Bangladesh Atomic Energy Commission
2022-2025

International Centre for Diarrhoeal Disease Research
2009-2022

University of Rajshahi
2018-2022

Chung-Ang University
2016-2020

Maternal exposure to the endocrine disruptor bisphenol A (BPA) has been linked offspring reproductive abnormalities. However, exactly how BPA affects fertility remains poorly understood.The aim of present study was evaluate effects gestational on sperm function, fertility, and proteome profile F1 spermatozoa in adult mice.Pregnant CD-1 mice (F0) were gavaged with at three different doses (50 μg/kg bw/day, 5 mg/kg 50 bw/day) embryonic days 7 14. We investigated related processes postnatal day...

10.1289/ehp378 article EN public-domain Environmental Health Perspectives 2016-07-06

Mortality in ducks and geese caused by highly pathogenic avian influenza A(H5N1) infection had not been previously identified Bangladesh. In June-July 2011, we investigated mortality ducks, chickens with suspected H5N1 a north-eastern district of the country to identify aetiologic agent extent outbreak possible associated human infections. We surveyed households farms affected poultry flocks six villages Netrokona collected cloacal oropharyngeal swabs from sick birds tissue samples dead...

10.1111/tbed.12354 article EN Transboundary and Emerging Diseases 2015-04-19

Studies regarding bisphenol A (BPA) exposure and male (in)fertility have conventionally focused on modifications in ejaculated spermatozoa function from exposed individuals. However, mammalian are incapable of fertilization prior to achieving capacitation, the penultimate step maturation. Therefore, it is necessary investigate BPA-induced changes capacitated assess consequences subsequent fertilization. Here, we demonstrate effect gestational BPA (50 μg/kg bw/day, 5 mg/kg 50 bw/day)...

10.1021/acs.jproteome.7b00668 article EN Journal of Proteome Research 2017-12-03

Abstract The endocrine disruptor bisphenol A (BPA) is well known for its adverse effect on male fertility. Growing evidence suggests that BPA may interact with testicular germ cells and cause infertility as a result of estrogenic activity. Objective current in vitro study was to investigate the proliferation, survivability stemness properties mouse exposed BPA, evaluate possible expression cellular proteome. Our results showed cell viability proliferation were not affected by low...

10.1038/s41598-017-12195-9 article EN cc-by Scientific Reports 2017-09-13

Burn has terrible consequences for the affected patients, making them vulnerable to wound infections and septicemia, which results in physical mental disability death, necessitating superior treatment options. Human amniotic membrane (HAM) been utilized burn wounds decades its low immunogenicity, angiogenic, anti‐inflammatory, antimicrobial properties promoting epithelialization. Silver nanoparticles (AgNPs), on other hand, have promote fibroblast migration. This study aimed determine...

10.1155/2023/9808556 article EN cc-by Evidence-based Complementary and Alternative Medicine 2023-01-01

Bisphenol-A (BPA) exposure in an adult male can affect the reproductive system, which may also adversely next generation. However, there is a lack of comprehensive data on BPA-induced disruption association and functional characteristics testicular germ cells, present study sought to investigate. Adult mice were administered BPA doses by gavage for six consecutive weeks allowed breed, producing generations F1–F4. Testis samples from each generation evaluated several parameters, including...

10.3390/ijms21155408 article EN International Journal of Molecular Sciences 2020-07-29

Abstract To explore Bangladesh's ability to detect novel influenza, we examined a series of laboratory-confirmed pandemic (H1N1) 2009 cases. During June–July 2009, event-based surveillance identified 30 case-patients (57% travelers); starting July 29, sentinel sites 252 (1% travelers). Surveillance facilitated response weeks before the spread infection general population.

10.3201/eid1801.101996 article EN cc-by Emerging infectious diseases 2012-01-01

Coronavirus disease 2019 (COVID-19) is a protean causing different degrees of clinical severity including fatality. In addition to humoral immunity, antigen-specific T cells may play critical role in defining the protective immune response against SARS-CoV-2, virus that causes this disease. As part longitudinal cohort study Bangladesh investigate B and cell-specific responses, we sought evaluate activation-induced marker (AIM) status cell subsets during COVID-19 infection. We analyzed total...

10.3389/fimmu.2022.929849 article EN cc-by Frontiers in Immunology 2022-09-28

ABSTRACT Background: Recent nutritional interventions have targeted colonic functions in patients with infectious diarrhea during rehydration and recovery from malnutrition, the assumption that effects will be influenced by metabolism of complex carbohydrates bacteria. However, diversity bacteria cholera is not known. Aim: To study malnourished children before treatment oral salt solutions containing 1 these 3 substrates: glucose, rice, or amylase‐resistant starch. Patients Methods: Serial...

10.1097/mpg.0b013e3181831867 article EN Journal of Pediatric Gastroenterology and Nutrition 2009-05-01

Exposure to bisphenol A (BPA) in the gestational period damages reproductive health of offspring; detailed evidence regarding BPA-induced damage testicular germ cells offspring is still limited. In this study, pregnant mice (F0) were gavaged with three BPA doses (50 μg, 5 mg, and 50 mg/kg body weight (bw)/day; tolerable daily intake (TDI), no-observed-adverse-effect-level (NOAEL), lowest-observed-adverse-effect level (LOAEL), respectively) on embryonic days 7 14, followed by investigation...

10.3390/ijms21228644 article EN International Journal of Molecular Sciences 2020-11-17

The longevity of immune responses induced by different degrees severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection provides information important to understanding protection against disease 2019 (COVID-19). Here, we report the persistence SARS-CoV-2 spike receptor-binding domain (RBD) specific antibodies and memory B cells recognizing this antigen in sequential samples from patients Bangladesh with asymptomatic, mild, moderate COVID-19 out six months following infection....

10.3389/fimmu.2022.1052374 article EN cc-by Frontiers in Immunology 2022-12-12

Many of the testicular cancer-survived patients, treated with chemotherapeutic drugs, show infertility, pre and postimplantation loss, germ cell abnormality. Studies examining negative effects drugs on cells are ongoing; however, information stemness properties proteomic profiles these lacking. This study investigated etoposide, cisplatin, bleomycin, their combination (BEP) physiology stem activity mouse in vitro. Our results showed that treatment abovementioned affected viability decreased...

10.1093/toxsci/kfy098 article EN Toxicological Sciences 2018-04-20

Bone tissue engineering aims to repair diseased or damaged bone that cannot be regenerated naturally. This study is designed develop biodegradable porous scaffolds as substitutes and evaluate the effect of gamma irradiation on these for restoration defected bone. Here, composite (HA-COL-CS-Mg-ZnO) were prepared by thermally induced phase separation (TIPS) technique using collagen (COL) chitosan (CS), hydroxyapatite (HA), magnesium (Mg), zinc oxide (ZnO) at different mass ratios. Thereafter,...

10.1155/2023/6682223 article EN cc-by International Journal of Polymer Science 2023-11-11

Objectives: In recent years, green synthesis of silver nanoparticles (AgNPs) has gained much interest from researchers as biomedical treatments. The purpose this study was to determine if AgNPs synthesized Hibiscus Sabdariffa L. bark extract are an effective stabilizing agent and inhibit Ehrlich ascites carcinoma (EAC) cell growth. Methods: were prepared by the reaction 0.6mM nitrate 5% extract. Synthesis confirmed UV-visible spectroscopy well characterized scanning electron microscopy,...

10.24079/cajms.2018.12.006 article EN cc-by-nc Central Asian Journal of Medical Sciences 2018-12-29

Background: Since chemical anticancer drugs are found to have adverse effect on body, nowadays people motivated towards natural agents treat cancer. Fruits and vegetables potential source of that protect our body against cancer by scavenging neutralizing free radicals. Objective: The study was aimed explore antioxidant properties methanolic extract leaves Hibiscus sabdariffa L. (MEHSL). Methods: In vitro assays were used examine the different types phytochemical content MEHSL. in vivo...

10.3329/bmrcb.v47i2.57774 article EN Bangladesh Medical Research Council Bulletin 2022-05-17

The development of biocompatible scaffolds is rapidly growing in several fields human health, particularly for the treatment bone defects. In this study, silver nanoparticle (AgNPs)-incorporated hydroxyapatite (HA), chitosan (Chi), and polyvinylpyrrolidone (PVP)-based were fabricated using freeze-drying method tissue engineering. Physicochemical properties such as porosity, density, swelling ratio, biodegradability, well blood biocompatibility, brine shrimp lethality, antibacterial...

10.1155/2023/9234962 article EN cc-by Advances in Materials Science and Engineering 2023-10-30
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