A5089538443- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Hepatitis B Virus Studies
- Hepatitis Viruses Studies and Epidemiology
- Child Nutrition and Water Access
- Viral gastroenteritis research and epidemiology
- COVID-19 epidemiological studies
- Intellectual Property and Patents
- Pneumonia and Respiratory Infections
- Clinical Nutrition and Gastroenterology
- Vibrio bacteria research studies
- Bacterial Infections and Vaccines
- Virology and Viral Diseases
- Escherichia coli research studies
- Antibiotic Resistance in Bacteria
- Hepatitis C virus research
- Parasitic Infections and Diagnostics
International Centre for Diarrhoeal Disease Research
2020-2025
Hepatitis E virus (HEV) is a major cause of acute viral hepatitis worldwide and it contributes to considerable maternal neonatal mortality morbidity in many low-income countries like Bangladesh. A three-dose regimen vaccine against HEV (HEV 239) has shown promising results China. The effects safety this other populations with different dosing regimens remains uncertain.Investigate the immune response two-dose 239 among healthy adults. Examine feasibility conducting larger trial rural...
Malnutrition in the early days of life is a global public health concern that affects children’s growth. It results from variety factors, including pathogenic infections. Enterocytozoon bieneusi microsporidian parasite can cause diarrhea and malnutrition children. The study aimed to assess impact E. on child MAL-ED study, multicountry birth cohort research project, investigated relationship between enteric infections participating children eight countries. A customized real-time polymerase...
Children suffering from severe acute malnutrition (SAM) have a weakened immune system. The relationship between and alterations in the frequency of peripheral blood mononuclear cells (PBMCs) remains unclear. This study investigated altered responses Bangladeshi children with SAM compared to healthy children. PBMCs were collected 24 25 upon their hospital admission after 21 days nutritional therapy at rehabilitation unit. Flow cytometry was employed assess various subsets T cells, B natural...
Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis worldwide. In many low-income countries it causes large outbreaks and disproportionally affects pregnant women their offspring. Surveillance studies to find effective preventive interventions are needed but hampered by lack funding infrastructure. Dried blood spots (DBS) offer an easier more robust way collect, transport, store samples compared plasma/serum samples, could ease some barriers for such studies. this study...
Coronavirus disease 2019 (COVID-19) is a protean causing different degrees of clinical severity including fatality. In addition to humoral immunity, antigen-specific T cells may play critical role in defining the protective immune response against SARS-CoV-2, virus that causes this disease. As part longitudinal cohort study Bangladesh investigate B and cell-specific responses, we sought evaluate activation-induced marker (AIM) status cell subsets during COVID-19 infection. We analyzed total...
The longevity of immune responses induced by different degrees severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection provides information important to understanding protection against disease 2019 (COVID-19). Here, we report the persistence SARS-CoV-2 spike receptor-binding domain (RBD) specific antibodies and memory B cells recognizing this antigen in sequential samples from patients Bangladesh with asymptomatic, mild, moderate COVID-19 out six months following infection....
After the large influx of Rohingya nationals (termed Forcibly Displaced Myanmar National; FDMN) from Rakhine State to Cox's Bazar in Bangladesh, it was apparent that outbreaks cholera very likely this setting where people were living under adverse water and sanitation conditions. Large campaigns oral vaccine (OCV) carried out as a preemptive measure control epidemics. The aim study evaluate immune responses healthy adults children after administration two doses OCV at 14 days interval FDMN...
Meningococcal disease is caused by Neisseria meningitidis or meningococcus. Every year globally around 1.2 million people are affected and approximately 120,000 deaths occur due to meningitis. The can be prevented a single dose of meningococcal vaccine. We carried out randomized observer-blinded non-inferiority trial evaluate compare the immunogenicity safety local polysaccharide vaccine 'Ingovax ACWY' (test) with Quadri MeningoTM (comparator), an approved in India. A total 88 healthy adults...
ABSTRACT COVID-19 caused by SARS-CoV-2 can develop the disease with different degree of clinical severity including fatality. In addition to antibody responses antigen specific T cells may play a critical role in defining this protective immune response against virus. As part longitudinal cohort study Bangladesh investigate B and cell responses, we sought evaluate activation induced marker (AIM) status subsets during infection. A total 115 participants were analyzed which included...