A5085002408- Cellular Mechanics and Interactions
- Cell Adhesion Molecules Research
- RNA and protein synthesis mechanisms
- Angiogenesis and VEGF in Cancer
- Protease and Inhibitor Mechanisms
- Bacterial Genetics and Biotechnology
- CRISPR and Genetic Engineering
- Hydrogels: synthesis, properties, applications
- Force Microscopy Techniques and Applications
- 3D Printing in Biomedical Research
Georgia Institute of Technology
2014-2017
AID Atlanta
2015
The Wallace H. Coulter Department of Biomedical Engineering
2014
Microgels are colloidally stable, hydrogel microparticles that have previously been used in a range of (soft) material applications due to their tunable mechanical and chemical properties. Most commonly, thermo pH-responsive poly(N-isopropylacrylamide) (pNIPAm) microgels can be fabricated by precipitation polymerization the presence co-monomer acrylic acid (AAc). Traditionally pNIPAm synthesized crosslinking agent, such as N,N'-methylenebisacrylamide (BIS), however, also under 'crosslinker...
Fibronectin (Fn) is an extracellular matrix protein that orchestrates complex cell adhesion and signaling through surface integrin receptors during tissue development, remodeling, disease, such as fibrosis. Fn sensitive to mechanical forces in its tandem type III repeats, resulting extensive molecular enlongation. As such, it has long been hypothesized cell- tissue-derived may activate "integrin switch" within the critical integrin-binding ninth 10th repeats—conferring differential...
Here, we present a universal, simple, efficient, and reliable way to add small BioBrick parts any via PCR that is compatible with assembly standard 10. As proof of principle, have designed universal primer, rbs_B0034, contains ribosomal binding site (RBS; BBa_B0034) can be used in amplify coding starts ATG. We performed test PCRs rbs_B0034 on 31 different targets found it 93.6% efficient. Moreover, when supplemented complementary addition RBS accomplished whole plasmid site-directed...