A5042069061- Child Nutrition and Water Access
- Food Security and Health in Diverse Populations
- Child Nutrition and Feeding Issues
- Poverty, Education, and Child Welfare
- Clinical Nutrition and Gastroenterology
- Infant Development and Preterm Care
- Global Maternal and Child Health
- Carcinogens and Genotoxicity Assessment
- Molecular Biology Techniques and Applications
- Agricultural Economics and Policy
- Seed and Plant Biochemistry
- Crop Yield and Soil Fertility
- Mycotoxins in Agriculture and Food
- Health Systems, Economic Evaluations, Quality of Life
Tufts University
2017-2022
Moderate acute malnutrition (MAM) affects 33 million children annually. Investments in formulations of corn-soy blended flours and lipid-based nutrient supplements have effectively improved MAM recovery rates. Information costs cost-effectiveness differences are still needed. We assessed sustained rates receiving a supplementary food: ready-to-use food (RUSF), corn soy whey blend with fortified vegetable oil (CSWB w/oil), or Super Cereal Plus amylase (SC + A) compared to Corn Soy Blend (CSB+...
Objectives To investigate the feasibility of eye-tracking-based testing speed visual orienting in malnourished young children at rural clinics Sierra Leone. Design Prospective dual cohort study nested a cluster-randomised trial. Setting 8 sites participating trial supplementary feeding for moderate acute malnutrition (MAM). Participants For MAM cohort, all infants aged 7–11 months eight were enrolled, 138 altogether. controls, convenience sample non-malnourished same eligible, 60 A 30 adults...
Measures that better describe "healthy" and sustainable recovery during nutritional treatment of children with moderate acute malnutrition (MAM) are needed. We compared changes to body composition among receiving 1 4 specialized nutritious food (SNFs) MAM by relapse outcomes. The study was nested within a prospective, cluster-randomized, community-based, cost-effectiveness trial assessing SNFs treat aged 6–59 mo [midupper arm circumference (MUAC) ≥11.5 cm <12.5 without bipedal edema] in...
This analysis describes differences in household-level use of four specialized nutritious foods (SNFs) for treatment moderate acute malnutrition (MAM) children 6–59 months age Sierra Leone and explores whether these behaviors influenced recovery. From 4/2017 to 11/2018, sub-samples caregivers whose were enrolled a supplemental feeding program (SFP) MAM study randomly selected in-depth interviews in-home observations. was cluster-randomized trial 2653 with evaluating cost-effectiveness 4...
ABSTRACT. Examining the role of environmental enteric dysfunction (EED) in child growth requires noninvasive, field-appropriate biomarkers. Alternatives to traditionally used lactulose:mannitol (L:M) test have been explored, but few studies compared L:M host fecal mRNA transcripts. The objectives this study were examine whether 1) transcripts could predict presence and severity EED, measured using test, 2) EED modifies effect specialized nutritious foods (SNFs) on recovery from moderate...
This study compared the effectiveness of 4 specialized nutritious foods (SNFs) used for treatment moderate acute malnutrition (MAM) in children <5 years age Pujehun District, Sierra Leone. was a cluster-randomized trial operating through supplementary feeding program (SFP) providing SNFs MAM. Three were fortified blended – Super Cereal Plus w/amylase (SC + A), Corn-soy Blend w/oil (CSB w/oil), and Corn-soy-whey (CSWB w/oil) one lipid-based Ready to Use Supplementary Food (RUSF). From 4/2017...
To examine factors associated with stunting in Agago District, Uganda We used cross-sectional data from a quantitative baseline survey of 870 households the ONCE (One Nutrition Complex Environments) project currently being conducted district Uganda. Survey include infant anthropometry, feeding practices, 24-hour dietary recall, maternal heights, weights, education and household characteristics. Statistical methods Pearson correlation coefficients, student T-tests, pair-wise mean comparisons...
It is widely recognized that cost‐effectiveness (CE) estimates generated by economic evaluations should enter into decision‐making for health and nutrition policy programming. However, many existing of interventions focus on effectiveness, assessing comparative outcomes without considering their associated costs. Moreover, despite recognizing the importance measuring costs in generating CE estimates, researchers find costing to be a challenging task with limited guidance few examples cost...
Abstract Objective To implement and measure the effects of a multi-level multi-sectoral social behavior change (SBC) intervention in Agago District Northern Uganda to determine potential for scale-up. Intervention Compare Nutrition Impact Positive Practice (NIPP) approach NIPP+ approach. The NIPP involves nutrition education SBC, whereas adds agricultural inputs, training, tools support improved farm water quality practices. effect will be measured through lower levels aflatoxin grain,...
The objective of the study was to examine whether EED at enrollment modifies effect specialized nutritious foods (SNFs) on graduation from a moderate acute malnutrition (MAM) treatment program. This sub-study nested within cluster randomized trial MAM children 6–59 months age supplemented with one four SNFs: Super Cereal Plus w/amylase (SC + A), Corn Soy Blend w/oil (CSB - referent), Whey (CSWB w/oil), and Ready Use Supplementary Food (RUSF). Children mid-upper arm circumference (MUAC) ≥11.5...
To estimate cost-effectiveness of 4 specialized nutritious foods (SNF) for Moderate Acute Malnutrition (MAM) treatment in children under five Pujehun District, Sierra Leone In a cluster randomized trial, mobile supplementary feeding program was set up at 29 peripheral health units to treat with MAM (mid-upper arm circumference (MUAC) ≥11.5 cm and <12.5 without bipedal edema) 1 iso-caloric rations: Corn Soy Blend Plus w/oil (CSB + w/oil, reference), Whey (CSWB w/oil), Super Cereal w/amylase...
To determine differential changes in children's body composition—fat-free mass (FFM) and fat (FM)—after 4 weeks of treatment for moderate acute malnutrition (MAM) with one four specialized nutritious foods (SNFs). This sub-study was nested within a larger cluster-randomized trial comparing the cost-effectiveness isocaloric SNFs treating MAM among children 6–59 months Pujehun District, Sierra Leone: Corn-Soy Blend Plus w/oil (CSB + w/oil), Super Cereal w/amylase (SC A), Corn-Soy-Whey (CSWB...
Fortified blended flours (FBFs) require preparation with boiling water, sometimes fortified vegetable oil (FVO), using prescribed quantities and ratios. Lipid-based nutrient supplements (LNS) are ready-to-eat, individually packaged, for consumption without adding other ingredients/foods. This study assessed compliance recipe ration instructions whether this influenced treatment effectiveness moderate acute malnutrition (MAM). A cluster-randomized clinical-effectiveness trial in Sierra Leone...
To assess factors associated with failure to respond treatment for moderate acute malnutrition (MAM) while enrolled in a supplementary feeding program (SFP) Pujehun District, Sierra Leone. This was secondary analysis of cluster-randomized trial. The main study examined the cost-effectiveness four specialized nutritious foods (SNFs) treating MAM children 6–59 months. Each SNF (Corn Soy Blend Plus, Corn Whey Blend, Super Cereal Plus Amylase, and Ready Use Supplementary Food) provided...
Two field studies assessed the effectiveness and cost-effectiveness of specialized nutritious foods (SNF) to prevent treat malnutrition among children 6–24 months old in Burkina Faso 6–59 Sierra Leone. In-home observations (IHO) were conducted understand household use SNFs. The IHO data are unique, as local enumerators directly observed caregiver behaviors that would otherwise be provided by self-report. In this study, we examined factors may influence child nutrition, including feeding,...
To examine differences in outcomes when using MUAC and/or WHZ to identify wasted children by sex Burkina Faso and Sierra Leone. Spearman's correlation was calculated the relationship between WHZ. Kappa Statistics were agreement identifying children. Sensitivity specificity of as benchmark for wasting calculated. There 6112 total (51% male); 2650 Leone (43% male). In Faso, both sexes significant (lowest r = 0.79, p < 0.001; highest 0.86, 0.001). Agreement two measures fair female (k 0.29,...