J Chen

ORCID: 0000-0001-7643-4778
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • Livestock and Poultry Management
  • Circular RNAs in diseases
  • RNA and protein synthesis mechanisms
  • Genetic and phenotypic traits in livestock
  • MicroRNA in disease regulation
  • Animal Nutrition and Physiology

Sichuan Animal Science Academy
2019-2022

Poultry Research Institute
2020

Abstract Background Long non-coding RNAs (lncRNAs) play an essential role in biological processes. However, the expression patterns of lncRNAs that regulate non-Mendelian inheritance feather phenotypes remain unknown. Objective This study aimed to compare profiles follicles late-feathering cocks (LC) and hens (LH) followed genetic rules early-feathering hen (EH) cock (EC) did not conform laws. Methods We performed RNA sequencing investigated differentially expressed (DElncRNAs) between...

10.1007/s13258-022-01304-2 article EN cc-by Genes & Genomics 2022-09-10

1. The Tibetan chicken, which is an indigenous breed living on the Plateau, exhibits hypoxic adaptations to its high-altitude environment. However, molecular mechanism behind this adaptation still unclear. This study aimed investigate differentially expressed miRNAs involved in through high-throughput RNA sequencing.2. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) was used verify and their target genes chicken embryonic heart tissues fibroblasts. Luciferase reporter...

10.1080/00071668.2020.1792835 article EN British Poultry Science 2020-07-07

Chinese indigenous chicken breeds are geographically widespread, and a total of 116 listed as national genetic resources. However, these facing serious challenges declining population germplasm degeneration because lots commercial had been introduced. In this study, the variations eleven Sichuan province three were investigated based on partial mitochondrial DNA D-loop 487bp in length. 147 individuals from 14 examined 34 haplotypes observed. Genetic diversity analysis showed that highest...

10.1590/1806-9061-2018-0807 article EN cc-by Brazilian Journal of Poultry Science 2019-01-01
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