Three new Ln2Ni (Ln = Gd, Sm, Tb) heterometallic compounds templated by C 2 O 4 2− anions were synthesized. The magnetic investigation showed that Gd2Ni displays an excellent low-field MCE (−Δ S m 25.1 J kg −1 K for 2.0 T at K).

Aim: The aim of this study was to assess the effect sitagliptin, a dipeptidyl peptidase‐4 inhibitor, on 24‐h glucose control when added regimen patients with type 2 diabetes who had inadequate glycaemic metformin therapy. Methods: In double‐blind, randomized, placebo‐controlled, two‐period crossover study, monotherapy (i.e. stable dose ≥1500 mg/day for ≥6 weeks prior screening visit and an haemoglobin A 1c (HbA ) ≥6.5% <10% fasting plasma (FPG) ≤240 mg/dl) were recruited participation....

Burn wound management is challenging, and while mesenchymal stem cell-derived exosomes show therapeutic potential, optimal delivery methods are unclear. To study chitosan (CS)-αβ-glycerophosphate (CS-αβ-GP) hydrogel crosslinked with adipose-derived cell (ASC-Exos) for healing deep burn injuries. Rats injuries were divided into the CS + ASCs-Exos group, control group. The rates on days 4, 7, 14 after treatment analyzed using ImageJ software. On day 14, tissues stained hematoxylin eosin...

Numerous natural products and drugs contain flexible alkyl chains. The resulting conformational motion can create challenges in obtaining single crystals thus determining their molecular structures by single-crystal X-ray diffraction (SCXRD)1-11. Here we demonstrate that using pillar[5]arene-incorporated metal-organic frameworks (MOFs) taking advantage of pillar[5]arene-alkyl chain host-guest recognition12-15, it is possible to reduce this bring order alkyl-chain-containing molecules as the...

Aim: The efficacy and safety of sitagliptin (SITA) monotherapy SITA/metformin (MET) vs. pioglitazone (PIO) were assessed in patients with type 2 diabetes moderate-to-severe hyperglycaemia (A1C = 7.5–12.0%). Methods: In an initial 12-week phase (Phase A), 492 randomised 1 : a double-blind fashion to SITA (100 mg qd) or PIO (15 qd, up-titrated 30 after 6 weeks). Phase B (28 additional weeks), the group was switched SITA/MET (up-titrated 50/1000 bid over 4 weeks) 45 qd Results: At end A, mean...

To investigate the effects of CA on glucocorticoid-induced osteoporosis (GIOP) and lucubrate underlying mechanism via activation polycystic kidney disease-1(PKD1) in bone marrow mesenchymal stem cells (BMSCs). In vivo, a GIOP model mice treated with dexamethasone (Dex) was established. Biomechanical, micro-CT, immunofluorescence staining OCN, ALP PKD1 others were severally determined. qRT-PCR Western blot methods adopted to elucidate particular mechanisms GIOP. addition, BMSCs cultured vitro...

Twenty‐eight novel ferrocenyl ionic compounds, composed of mononuclear 1‐ferrocenylmethylalkyldimethylammoniums, 1‐ferrocenylmethyl‐3‐alkylimidazoliums, or their dinuclear analogs and [Fe(CN) 6 ] 3– anion, were designed synthesized to tackle significant volatility migration tendency ferrocene‐based burning rate catalysts (BRCs) used currently in the composite solid propellants. The new compounds characterized by UV/Vis, FT‐IR, elementary analysis. crystal structures 2· 5H 2 O 3· CH Cl · 4H...

Electronic and steric effects of substituents alkynyl ketones play important roles in regulating reaction pathways.

Alkylferrocene‐based burning‐rate catalysts (BRCs) exhibit distinct migration tendency and high volatility thus result in inferior performance of composite solid propellants during their combustion processes. To deal with these drawbacks, a novel dinuclear nitrogen‐rich ferrocene derivative, 4‐amino‐3,5‐bis(4‐ferrocenyl‐1,2,3‐triazolyl‐1‐methyl)‐1,2,4‐triazole (BFcTAZ) its twenty seven ionic coordination compounds, [ M 2 (H O) 4 ] m X n · x H O ( = Cr 3+ , Mn 2+ Fe Co Ni Cu Zn Cd Pb ;...

The reaction of Ru3(CO)12 with ferrocene-containing alkynyl ketones FcC[triple bond, length as m-dash]CC(O)R (Fc = ferrocenyl; R Ph (1); 2-thienyl (2); 4-CH3O-Ph (3); 4-NH2-Ph (4); 4-NO2-Ph (5); ferrocenyl (6)) proceeds in toluene the formation triruthenium clusters (1a-6a), ruthenoles (1b-5b, 5c and 1d-5d) unexpected 1,2-CO-inserted (1c-4c). 1a-6a were isolated from one equivalent 1-6, respectively. Ruthenoles 1b-5b, 1d-5d collected by adding 1-5 to corresponding 1a-5a a molar ratio 1 : 1,...

Abstract A novel amine moiety‐based fluorescent probe ( BA) was prepared using diphenylacetylene as fluorophore and amino group acceptor. The achieves detection of formaldehyde through fluorescence enhancement by inhibition the photoinduced electron transfer (PET) between group. And different performance 2‐(phenylethynyl)aniline BA‐1 ), 3‐(phenylethynyl)aniline BA‐2 ) 4‐(phenylethynyl)aniline BA‐3 indicates that position recognition on benzene ring has a significant impact ability this type...

<title>Abstract</title> Objective This study aimed to explore the effects on controlling infection and promoting wound healing in deep burn injuries by crosslinking ASCs-Exos with CS-αβ-GP thermosensitive hydrogel. Methods Rats established injury models were divided into four groups: CS + group, control group. The rates analyzed calculated using Image J software immediately after formation days 2, 4, 6, 8, 10, 12, 14 treatment. Fourteen treatment, skin tissues from area, margin, normal...

Electronic and steric effects of the substituents in 1,3-ynones play key roles product distribution molecular structures.

In the title complex, [Zn(C(15)H(10)O(6))(H(2)O)(2)](n), Zn(II) atom is located on a twofold rotation axis and exhibits distorted tetrahedral coordination environment defined by two O atoms from 4,4'-(methyl-enedioxy)-dibenzoate ligands coordinated water mol-ecules. crystal structure, mol-ecules are linked into three-dimensional framework O-H⋯O hydrogen bonds C-H⋯π inter-actions.

The strong coordination ability of nitrogen atoms N-heterocyclic groups plays key roles in the product distribution and molecular structures.