A5022435318- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Renal and related cancers
- Urological Disorders and Treatments
- Prostate Cancer Diagnosis and Treatment
- Renal and Vascular Pathologies
- Urinary and Genital Oncology Studies
- Organ Donation and Transplantation
- Prostate Cancer Treatment and Research
- Pediatric Urology and Nephrology Studies
- Ureteral procedures and complications
- Urologic and reproductive health conditions
- Surgical Simulation and Training
- Minimally Invasive Surgical Techniques
- Urinary Bladder and Prostate Research
- Tissue Engineering and Regenerative Medicine
- Testicular diseases and treatments
- Adrenal and Paraganglionic Tumors
- Pituitary Gland Disorders and Treatments
- Anatomy and Medical Technology
- Sexual Differentiation and Disorders
- Algorithms and Data Compression
- Cardiac, Anesthesia and Surgical Outcomes
- Medical and Health Sciences Research
- Pancreatic and Hepatic Oncology Research
Saarland University
2015-2025
Universitätsklinikum des Saarlandes
2012-2024
University of Göttingen
2022-2024
Centro de Investigación Docencia y Consultoria Administrativa
2024
St.-Antonius-Hospital Gronau
2024
University Medical Center
2014-2016
KU Leuven
2016
Centre Alexandre Koyré
2016
University Hospital and Clinics
2016
Hamburg Institut (Germany)
2016
We report the cloning and characterization of a tumor-associated carbonic anhydrase (CA) that was identified in human renal cell carcinoma (RCC) by serological expression screening with autologous antibodies. The cDNA sequence predicts 354-amino acid polypeptide molecular mass 39,448 Da has features type I membrane protein. predicted includes 29-amino signal sequence, 261-amino CA domain, an additional short extracellular segment, 26-amino hydrophobic transmembrane hydrophilic C-terminal...
To explore the views of experts about development and validation a robotic surgery training curriculum, how this should be implemented. An international expert panel was invited to structured session for discussion. The study mixed design, including qualitative quantitative components based on focus group interviews during European Association Urology (EAU) Robotic Section (ERUS) (2012), EAU (2013) ERUS meetings. After introduction aims, principles current status curriculum development,...
What's known on the subject? and What does study add? There is evidence from large abdominal surgeries some open cystectomy series that multifactorial fast‐track regimens shorten postoperative convalescence without any effect morbidity mortality. Such a regimen of particular interest in combination with minimally invasive techniques, as early patient recovery demands for more rapid nutrition mobilisation schemes. The present study, single institution, reports design, application results...
The purpose of this study was to investigate the effect a surgically constructed bilateral peritoneal flap (PIF) as an adjunct robot-assisted radical prostatectomy (RARP) and pelvic lymph node dissection (PLND) on incidence lymphoceles.A total 530 men with localized prostate cancer underwent RARP extended standardized PLND in prospective randomized controlled trial. In group A, PIF created by suturing margins bladder peritoneum ipsilateral endopelvic fascia at 2 points each side. B, no...
Little is known regarding functional outcomes after robot-assisted radical cystectomy (RARC) and intracorporeal neobladder (ICNB) reconstruction. To report on urinary continence (UC) erectile function (EF) at 12 mo RARC ICNB reconstruction investigate predictors of these outcomes. We used data from a multi-institutional database patients who underwent for bladder cancer. The cystoprostatectomy sensu stricto followed the conventional steps. was performed physician's discretion according to...
The highest CK2 activity was found in mouse testicles and brain, followed by spleen, liver, lung, kidney heart. values were directly correlated with the protein expression level of subunits α (catalytic) β (regulatory). α′ subunit only detected brain testicles. By contrast, Northern blot analyses CK2α mRNA revealed a somewhat different picture. Here, strongest signals obtained for heart lung. In kidney, spleen mRNAs weakly detectable. For CK2α′ distribution strong observed liver case CK2β...
: Recent studies of rare cases pT3a renal cell carcinoma extending directly into the adrenal gland showed worse survival than in other and recategorization as stage pT4 was suggested. We assessed prognostic validity a diagnosis based on perirenal fat infiltration.: The records 1,794 patients with who underwent surgical resection between 1975 2000 at our institution were analyzed retrospectively. Focusing tumors, defined by infiltration, numerous clinical histopathological parameters...
Background Does the dogma of nephron sparing surgery (NSS) still stand for large renal masses? Available studies dealing with that issue are considerably biased often mixing imperative elective indications NSS and also including less malignant variants or even benign tumors. Here, we analyzed oncological long-term outcomes patients undergoing radical tumor nephrectomy (RN) non-endophytic, (≥7cm) clear cell carcinoma (ccRCC). Methods Prospectively acquired, clinical databases from two...
Abstract Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome is caused by heterozygous germline variants in the fumarate hydratase (FH) gene [1,2]. Inheritance follows an autosomal dominant pattern. Loss of FH confers a predisposition for various benign malignant neoplasms, including cutaneous leiomyomas, uterine fibroids FH-deficient [3]. While benign, manifestations have relevant impact on quality life risk complications [4]. The vast majority RCC exhibit aggressive...
Ureterocalicostomy refers to the anastomosis of lower pole calyces with ureter after excision hydronephrotic renal (1, 2). Indications for ureterocalicostomy include previous failed pyeloplasty, ureteropelvic junction obstruction (UPJO) anatomical abnormalities, such as intrarenal pelvis or short (3) and proximal ureteral strictures (4). The purpose this video is demonstrate technique Robotic-Assisted Laparoscopic (RALUC) in a patient UPJO pelvis. Preoperatively, retrograde...
What's known on the subject? and What does study add? Lymph node dissection it's extend during robot‐assisted radical cystectomy varies based surgeon related factors. This reports outcomes of extended lymphadenectomy experience in both academic private practice settings. Objective To evaluate incidence of, predictors for, lymph ( LND ) patients undergoing RARC for bladder cancer, as is critical treatment cancer but role minimally invasive surgery has not been well‐defined a...
To compare, in a retrospective observational cohort study, the efficacy, tolerability and safety of propiverine oxybutynin children with urge incontinence (UI) due to overactive bladder.Medical records were scrutinized for UI. As primary efficacy outcome variable achievement continence after treatment doses or was assessed. Weekly UI episodes daily voiding frequency evaluated as secondary outcomes. Tolerability by rate adverse events, drug reactions caused antimuscarinics premature...
Urge incontinence and voiding postponement are common subtypes of daytime wetting in children. We analyzed health related quality life for children with urge postponement, healthy controls at 2 centers.We examined a total 49 consecutive 5 to 13 years old who presented (22) or (27), 32 matched age sex. Health overall were measured generic questionnaires, self-esteem was the Piers-Harris questionnaire.Health significantly reduced parent rating but not child incontinent vs control group (total...