A5034542387- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Lanthanide and Transition Metal Complexes
- Hepatocellular Carcinoma Treatment and Prognosis
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Cardiac Imaging and Diagnostics
- Knee injuries and reconstruction techniques
- Musculoskeletal synovial abnormalities and treatments
- Vascular Anomalies and Treatments
- Total Knee Arthroplasty Outcomes
- Tracheal and airway disorders
- Neonatal and fetal brain pathology
- Advanced Radiotherapy Techniques
- Cancer, Hypoxia, and Metabolism
- Prostate Cancer Diagnosis and Treatment
- Aortic aneurysm repair treatments
- Liver Disease and Transplantation
- Renal and related cancers
- Renal cell carcinoma treatment
- Cardiovascular Effects of Exercise
- Parvovirus B19 Infection Studies
- Neuroblastoma Research and Treatments
Saarland University
2013-2024
University Hospital and Clinics
2021
University Medical Center
2021
Universitätsklinikum des Saarlandes
1999-2014
University of Graz
1988
Metabolic dysfunction-associated steatotic liver disease is a growing global public health concern. Quantitative ultrasound measurements, such as ultrasound-derived fat fraction (UDFF), could provide noninvasive, cost-effective, and portable steatosis evaluation.
Cardiac troponins I and T brain natriuretic peptide are the accepted standards to serologically identify myocardial necrosis elevated wall stress. In addition, they allow risk stratification in cardiovascular patients. The clinical significance of increases cardiac markers after strenuous endurance exercise obviously healthy athletes is unclear. We therefore examined reproducibility exercise-induced N-terminal pro two standardized trials with prior competition-induced elevations (I,...
: Recent studies of rare cases pT3a renal cell carcinoma extending directly into the adrenal gland showed worse survival than in other and recategorization as stage pT4 was suggested. We assessed prognostic validity a diagnosis based on perirenal fat infiltration.: The records 1,794 patients with who underwent surgical resection between 1975 2000 at our institution were analyzed retrospectively. Focusing tumors, defined by infiltration, numerous clinical histopathological parameters...
The purpose of our study was to evaluate contrast-enhanced MR angiography (CE-MRA) as a screening procedure for the detection pulmonary arteriovenous malformations (AVMs) in patients with hereditary hemorrhagic telangiectasia (HTT).Two hundred three consecutive subjects (patients diagnosed HHT or first-degree relatives; 87 males, 116 females; 6-83 years old) underwent CE-MRA 0.1 mmol/kg gadobenate dimeglumine. presence AVM scored 0 (none present), 1 (definitely 2 (uncertain) and evaluated by...
The aim of this proof-of-principle study was to evaluate contrast-enhanced sonography in the characterization adrenal masses.Thirty-five consecutively registered patients with newly detected masses underwent hormonal evaluation and duplex Doppler followed by CT or MRI. dynamics contrast enhancement were analyzed time-intensity curves. MRI used as reference methods for diagnosis adenoma myelolipoma. Metastasis diagnosed fine-needle biopsy, all other at adrenalectomy. Fisher's exact test...
<h3>BACKGROUND AND PURPOSE:</h3> Gadobenate dimeglumine has proved advantageous compared with other gadolinium-based contrast agents for contrast-enhanced brain MR imaging. Gadobutrol is a more highly concentrated agent (1.0 mol/L). This study intraindividually 0.1-mmol/kg doses of these qualitative and quantitative evaluation tumors. <h3>MATERIALS METHODS:</h3> Adult patients suspected or known tumors underwent 2 identical imaging examinations at 1.5T, 1 gadobenate the gadobutrol, both dose...
7506 Background: RT to bulky sites improves outcome of elderly DLBCL patients [Lancet Oncol 2008; 9: 105-116; J Clin 2014; 32:112-1118]. Whether can be spared in PET-negative pts. after R-CHOP was prospectively addressed OPTIMAL >60. Methods: 61 80 y-old were randomized a 2x2 factorial design 6xCHOP-14 or 6xCHLIP-14 (liposomal instead conventional vincristine) plus 8 x rituximab 375 mg/m 2 (R) q wks. 12xR (days -4,-1,1,4,14,28,42,56,91,126,175, 238). Pts. with bulk (>=7.5 cm)...
Abstract Diffuse neonatal hemangiomatosis (DNH) is a rare, frequently fatal disorder characterized by multiple cutaneous and visceral hemangiomas. Complications include high‐output cardiac failure, hemorrhage, hepatic consumption coagulopathy. We present two cases of neonates with DNH. prescribed cyclophosphamide after failure corticosteroids. Cyclophosphamide induced fast regression the lesions no side effects in both infants. were able to stop treatment 3–4 courses infants because...
<h3>BACKGROUND AND PURPOSE:</h3> Signal intensity increases possibly suggestive of gadolinium retention have recently been reported on unenhanced T1-weighted images the pediatric brain following multiple exposures to gadolinium-based MR contrast agents. Our aim was determine whether T1 signal changes deposition occur in brains nonneurologic patients after gadobenate dimeglumine. <h3>MATERIALS METHODS:</h3> Thirty-four (group 1; 17 males/17 females; mean age, 7.18 years) who received between...
Purpose To evaluate glass-fiber-based guidewires that are safe for magnetic resonance (MR) imaging-guided endovascular interventions by using a phantom and an in vivo swine model. Materials Methods MR imaging-safe were made from micropultruded glass and/or aramid fibers epoxy resin with diameters of 0.89 mm (0.035 inch) standard stiff 0.36 (0.014 micro guidewires. imaging visibility mechanical properties assessed pulsatile flow After approval was obtained the institutional animal care use...
The study was designed to evaluate diffusion-weighted magnetic resonance imaging (DWI) vs. PET-CT of the thorax in determination gross tumor volume (GTV) radiotherapy planning non-small-cell lung cancer (NSCLC).Eligible patients with NSCLC who were supposed receive definitive radio(chemo)therapy prospectively recruited. For MRI, a respiratory gated T2-weighted sequence axial orientation and non-gated DWI (b = 0, 800, 1,400 apparent diffusion coefficient map [ADC]) acquired on 1.5 Tesla...
Surgical resection is the therapy of choice for hepatic malignancy and yet only 30 per cent patients with primary lesions 10-20 those liver metastases are potential candidates 1 .Since 1994, authors have offered irresectable tumours open cryosurgery using high-performance cryoprobes as an alternative treatment.The aim this investigation was to evaluate whether percutaneous cryotherapy (PHCT) may be considered in a selected group
This prospective multicenter intraindividual crossover study was designed to compare gadobenate dimeglumine and gadofosveset trisodium at approved doses with respect the image quality diagnostic performance of contrast-enhanced MR angiography (CE-MRA) in detection clinically relevant renal artery stenosis.Thirty-nine subjects (17 men, 22 women; age range, 30-86 years; mean 62 +/- 13.3 [SD] years) known or suspected renovascular disease underwent a first CE-MRA examination 0.1 mmol/kg second...
Introduction . Sacropexy is a generally applied treatment of prolapse, yet there are known possible complications it. An essential need exists for better alloplastic materials. Methods Between April 2013 and June 2014, we performed modified laparoscopic bilateral sacropexy (MLBS) in 10 patients using MRI-visible PVDF mesh implant. Selected had prolapse POP-Q stages II-III concomitant OAB. We studied surgery-related morbidity, anatomical functional outcome, mesh-visibility MRI. Mean follow-up...
Abstract Purpose To demonstrate both MRI and histopathological findings of hepatocellular adenomas (HCAs) in men. Materials Methods HCAs four men are reported. All patients underwent MR studies at 1.5T including serial gadolinium‐enhanced gradient echo imaging. Results Three had solitary non‐hemorrhagic that exhibited a uniform capillary blush with no central scar, fading the tumor to near isointensity liver parenchyma by one minute. One subjects fat content as shown low signal on...
Background and aims: Classic autosomal-dominant familial adenomatous polyposis (FAP) is clinically defined by the development of hundreds to thousands colorectal adenomas beginning in childhood adolescence. A variant FAP characterized combination with osteomas or soft tissue tumours called Gardner's syndrome. caused germline inactivation APC (adenomatous coli) tumour-suppressor gene located on long arm chromosome 5 (5q21–5q22). Cytogenetically visible deletions 5q encompassing have very...