- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Hemophilia Treatment and Research
- Vascular Malformations and Hemangiomas
- Blood Coagulation and Thrombosis Mechanisms
- Blood donation and transfusion practices
- Autoimmune and Inflammatory Disorders Research
- Spinal Dysraphism and Malformations
- Vascular Malformations Diagnosis and Treatment
- Osteomyelitis and Bone Disorders Research
- DNA Repair Mechanisms
- Lymphoma Diagnosis and Treatment
- Cutaneous lymphoproliferative disorders research
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pharmaceutical studies and practices
- Chronic Myeloid Leukemia Treatments
- Infectious Diseases and Tuberculosis
- Blood groups and transfusion
- Antiplatelet Therapy and Cardiovascular Diseases
- Iron Metabolism and Disorders
- Platelet Disorders and Treatments
- Orthopedic Infections and Treatments
- T-cell and Retrovirus Studies
- Hemoglobinopathies and Related Disorders
Chulalongkorn University
2020-2024
King Chulalongkorn Memorial Hospital
2021-2024
Chiang Mai University
2018
The conventional treatment of Kasabach-Merritt Phenomenon (KMP) consists corticosteroids with vincristine/vinblastine or others. aim the study is to compare first-year direct costs and effectiveness between sirolimus treatment. A retrospective case-control KMP patients was conducted at a mean age 9 months (1 day 12 years) 2000 2022 from four tertiary centers in Thailand. costs, hematologic clinical complete response (HCR, CCR), hospitalization, length stay, complications were compared. Of 29...
Background: We identified 3 adolescents with alpha-beta subtype subcutaneous panniculitis-like T-cell lymphoma. Case Presentation: Three patients presented prolonged fever, abnormal skin lesions, and cytopenia described in the context. All had same disease entity, which showed duration of B systemic symptoms till diagnosis, difficulty to distinguish from autoimmune diseases, presence hemophagocytic lymphohistiocytosis syndrome, good response, remained on long-term remission nonchemotherapy...
Background: Asparaginase is one of the essential chemotherapies used to treat acute lymphoblastic leukemia (ALL). antibody production may cause a subtherapeutic level and result in an inferior outcome. Methods: Prospective study asparaginase activity among patients who received native E.coli 10,000 IU/m2 according ThaiPOG ALL protocol. The measured by coupled enzymatic reaction. Pharmacokinetic data includeding peak (Cmax), time maximum concentration (Tmax), area under curve (AUC0-48h) being...
In our 19 years’ experience at King Chulalongkorn Memorial Hospital, we were able to observe 21 pediatric cases with anaplastic large cell lymphoma (ALCL). Of these cases, 4 (19% of ALCL cases) had concurrent hemophagocytic lymphohistiocytosis (HLH). All developed fever, lymphadenopathy and exaggerated signs capillary leakage syndrome such as generalized edema, pleural effusion or ascites. The hyperinflammation was demonstrated hypoalbuminemia elevated inflammatory markers. A high index...
Since aspirin resistance is rarely assessed in pediatric patients and thrombosis might cause damage vital organs, such as the myocardium or brain, we aimed to determine its incidence pivotal role of routine screening. The point-of-care test by platelet function analyzer (PFA-200) bedside bleeding time (BT) was compared standard whole blood impedance aggregometry (IA), time-consuming sophisticated assays. This single-center cross-sectional study investigated Thai children (≤15 years). All...
Background: Congenital and acquired bleeding disorders present with various symptoms ranging from mild to severe manifestation. In recent years, attempts have been made apply histories in questionnaires predict the risk of describe symptoms’ severity. The Pediatric Bleeding Assessment Tool (BAT) is a pediatric-specific checklist set that has accepted worldwide was translated multiple languages including Thai. Objectives: (a) study aimed test validity reliability self-administered BAT compare...
Torchareon, Teesit MD; Chaweephisal, Phumin Akkawat, Benjaporn BSc; Sosothikul, Darintr MD Author Information
Chest wall mass in infancy is rare. Malignant lesions are more common than infection or benign tumors. This a case of 12-month-old girl who presented with 2 cm at the right costal margin and poor weight gain. radiograph demonstrated moth-eaten osteolytic lesion 8th rib. The resection was performed, pus content found. positive acid fast stain (AFB) organism noted. Pathology confirmed caseous granulomatous inflammation compatible mycobacterial infection. However, QuantiFERON-TB Gold negative,...
Asparaginase is one of the essential chemotherapies used to treat acute lymphoblastic leukemia (ALL). antibody production may cause a subtherapeutic level and result in an inferior outcome. The aim this study was prove efficacy current native E.coli asparaginase-based protocol. Moreover, does appeared small group trial?.A prospective asparaginase activity among patients who received 10,000 IU/m2 intramuscularly according Thai Pediatric Oncology Group (ThaiPOG) protocol done. plasma measured...