A5016623207- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Gastrointestinal disorders and treatments
- Cancer Genomics and Diagnostics
- Neuroendocrine Tumor Research Advances
- Gallbladder and Bile Duct Disorders
- Epigenetics and DNA Methylation
- IgG4-Related and Inflammatory Diseases
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease Diagnosis and Treatment
- Esophageal and GI Pathology
- Pediatric Hepatobiliary Diseases and Treatments
- Lung Cancer Research Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Abdominal vascular conditions and treatments
- Bariatric Surgery and Outcomes
- Intestinal Malrotation and Obstruction Disorders
- Neuroblastoma Research and Treatments
- Colorectal Cancer Screening and Detection
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- AI in cancer detection
- Biliary and Gastrointestinal Fistulas
- Pancreatic function and diabetes
Mayo Clinic in Arizona
2016-2025
Mayo Clinic
2016-2025
WinnMed
2015-2025
Jadavpur University
2024
Medtronic (Ireland)
2024
Hartford Financial Services (United States)
2019
Mayo Clinic in Florida
2015-2018
Saint Peter's University Hospital
2016-2017
Rutgers, The State University of New Jersey
2016-2017
UConn Health
2011-2015
Objective The diagnosis of autoimmune pancreatitis (AIP) is challenging. Sonographic and cross-sectional imaging findings AIP closely mimic pancreatic ductal adenocarcinoma (PDAC) techniques for tissue sampling are suboptimal. These limitations often result in delayed or failed diagnosis, which negatively impact patient management outcomes. This study aimed to create an endoscopic ultrasound (EUS)-based convolutional neural network (CNN) model trained differentiate from PDAC, chronic (CP)...
Intraductal papillary mucinous neoplasms (IPMNs) are pancreatic cysts that can give rise to cancer (PC). Limited population data exist on their prevalence, natural history, or risk of malignant transformation (IPMN-PC).
Abstract Purpose: We have previously identified tissue methylated DNA markers (MDMs) associated with pancreatic ductal adenocarcinoma (PDAC). In this case–control study, we aimed to assess the diagnostic performance of plasma MDMs for PDAC. Experimental Design: Thirteen (GRIN2D, CD1D, ZNF781, FER1L4, RYR2, CLEC11A, AK055957, LRRC4, GH05J042948, HOXA1, PRKCB, SHISA9, and NTRK3) were on basis selection criteria applied results prior experiments assays optimized in plasma. Next, 340 samples...
Pancreatic cystic lesions (PCLs) may be precancerous. Those likely to harbor high-grade dysplasia (HGD) or pancreatic cancer (PC) are targets for surgical resection. Current algorithms predict advanced neoplasia (HGD/PC) in PCLs lack diagnostic accuracy. In tissue and cyst fluid (CF) from PCLs, we sought identify validate novel methylated DNA markers (MDMs) that discriminate HGD/PC low-grade (LGD) no (ND).From an unbiased whole-methylome discovery approach using predefined selection criteria...
BACKGROUND: There is lack of consensus on post-operative surveillance for resected non-invasive intraductal papillary neoplasms (IPMNs). In this study we explored risk factors subsequent PC in patients with MD-IPMN undergoing partial pancreatectomy. METHODS: We searched the Mayo Clinic surgical pathology database all cases between 1997 and 2014. Cases histologically confirmed main pancreatic duct involvement either isolated or a mixed pattern branch-duct were included. Outcomes remnant...
Image-guided radiation therapy allows precise tumor targeting using real-time tracking of radiopaque fiducial markers. To enable appropriate tracking, it is recommended to place fiducials with "ideal geometry" (IFG). Our objectives were determine the proportion patients in whom IFG can be achieved when are placed by endoscopic ultrasound (EUS) and surgery if attaining necessary for delivering radiation.This single-center retrospective cohort study included 77 biopsy-proven advanced...