A5012503000- Epilepsy research and treatment
- Neonatal and fetal brain pathology
- Pharmacological Effects and Toxicity Studies
- Cerebrospinal fluid and hydrocephalus
- Neuroscience and Neuropharmacology Research
- Metabolism and Genetic Disorders
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Healthcare and Venom Research
- Vascular Malformations Diagnosis and Treatment
- Head and Neck Surgical Oncology
- EEG and Brain-Computer Interfaces
- Spinal Fractures and Fixation Techniques
- Spinal Hematomas and Complications
- Pediatric Hepatobiliary Diseases and Treatments
- Glioma Diagnosis and Treatment
- Anatomy and Medical Technology
- Ion channel regulation and function
- Mitochondrial Function and Pathology
- Antimicrobial Peptides and Activities
- Traumatic Brain Injury and Neurovascular Disturbances
- Lipid Membrane Structure and Behavior
- Drug Transport and Resistance Mechanisms
- Fetal and Pediatric Neurological Disorders
- Anesthesia and Neurotoxicity Research
Fujian Medical University
2017-2019
Fuzhou General Hospital of Nanjing Military Command
2002-2015
Aim . To assess the surgical outcomes of temporo‐parieto‐occipital (TPO) and parieto‐occipital (PO) disconnection surgery for children with intractable posterior quadrantic epilepsy a unilateral quadrant lesion based on MRI functional imaging abnormality in TPO region one side. Methods A retrospective review data 12 who underwent or PO disconnective was carried out from September 2009 to 2012. Three‐dimensional surface reconstructions scans intraoperative electrophysiological monitoring were...
OBJECT The objectives of this study were to describe a novel minimal-access subtemporal approach for selective resection the amygdala and hippocampus in patients with medically refractory mesial temporal lobe epilepsy (MTLE) due hippocampal sclerosis, analyze related outcomes. METHODS authors analyzed data from all cases involving unilateral MTLE sclerosis who treated amygdalohippocampectomy via posterior through relatively small craniotomy, without neuronavigation system, at their...
Scorpion venom is a Chinese medicine for epilepsy treatment, but the underlying mechanism not clear. heat-resistant peptide (SVHRP), isolated from of Buthus martensii Karsch, has an anti-epileptic effect by reducing seizure behavior according to modified Racine scale. The present study aimed investigate molecular SVHRP on temporal lobe epilepsy. hippocampus and hippocampal neurons kainic acid-induced epileptic rats were treated with at different doses duration. Quantitative RT-PCR...
Abstract Cerebral cavernous malformations (CMs) are vascular affecting any part of the central nervous system. Clinical data and surgical outcomes for 27 pediatric patients with CM-related epilepsy were retrospectively reviewed. The mean age onset was 12.71 ± 4.09 years, duration 2.34 1.95 years. All treated microsurgery resection CMs, hemosiderin rim, secondary epileptogenic zone if necessary. follow-up period 6.34 3.35 overall postoperative positive. Note that 77.8% seizure-free...
Magnetic resonance imaging (MRI)-negative epilepsy is associated with poor clinical outcomes prognosis. The present study was aimed to assess whether intracranial 3D interictal and ictal electroencephalography (EEG) findings, a combination of EEG at different depth, in addition clinical, scalp EEG, positron emission tomography–computed tomography (PETCT) data help predict outcome series patients MRI-negative frontal lobe (FLE) after surgery. Patients FLE who were presurgically evaluated by...
Objective To explore the surgical skills, therapeutic effects and complications of selective amygdalohippocampectomy via inferior temporal gyrus approach for treatment mesial lobe epilepsy (MTLE). Methods Sixty-two patients with medically intractable MTLE underwent amygdalohippocampectomy. Temporal keyhole craniotomy was performed, mid-anterior segment resected to access anterolateral floor horn. The structures such as amygdale parahippocampal were selectively resected. Results All followed...
Objective To discuss the selection of diagnosis for intracranial aneutysms,and to analyze thera-peutic efficacy microsurgical treatment and endovascular embolizafion in aneurysms.Methods 190 pailents suffeming from aneurysms experienced brain CT examination.37 cases detected by MRI.31 MRA,134 were confirmed computered tomographic angiography(CTA)or 3D-CTA,and 142 digital subtract angiography(DSA).96 patients underwent treatment,4 whom failed embolization.92 endovascufar therapy,2 embolized...
Objective To investigate the value of neuronavigation in microsurgery for medically refractory epilepsy. Methods The clinical data 137 patients with epilepsy who underwent surgery our hospital from September 2008 to 2016 were analyzed retrospectively. In these patients, 17 accepted temporal parietal occipital dissection, 23 corpus callosum subtotal 11 functional cerebral hemispheric and 86 foci resection. The surgical efficacies analyzed. Results All uneventfully operations as...