A5021186072- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Porphyrin and Phthalocyanine Chemistry
- Surface Modification and Superhydrophobicity
- TiO2 Photocatalysis and Solar Cells
- Plasma Applications and Diagnostics
- Dental materials and restorations
- Electrospun Nanofibers in Biomedical Applications
- Luminescence and Fluorescent Materials
Yonsei University
2011-2016
The principle of photodynamic treatment (PDT) involves the administration photosensitizer (PS) at diseased tissues, followed by light irradiation to produce reactive oxygen species (ROS). In cells, a moderate increase in ROS plays an important role as signaling molecule promote cell proliferation, whereas severe causes damage. Previous studies have shown that low levels stimulate growth through PS drugs-treating PDT and nonthermal plasma treatment. However, these methods side effects which...
Pheophorbide-a derivatives have been reported to be potential photosensitizers for photodynamic therapy (PDT). In this study, photophysics of pheophorbide-a (PaDs) were investigated along with their tumoricidal effect in vitro . PaDs modified by changing the coil length and/or making hydroxyl group (–OH) substitutions. Their photophysical properties studied steady-state and time-resolved spectroscopic methods. The was evaluated mouse breast cancer cell line (EMT6). Lifetime quantum yield...
We report the fabrication of photofunctional Co-Cr alloy plate that is prepared by a simple modification process for photodynamic application. Photoinduced functionality provided photosensitizer hematoporphyrin (Hp) initially generates reactive oxygen species (ROS) such as superoxide anion radical and singlet oxygen. The with carboxyl group was chemically bonded to surface esterification reaction. Microstructure elemental composition were checked scanning electron microscopy (SEM) energy...