A5029968746- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Porphyrin and Phthalocyanine Chemistry
- Advanced Photocatalysis Techniques
- Luminescence and Fluorescent Materials
- Analytical Chemistry and Sensors
- Supercapacitor Materials and Fabrication
- Photochromic and Fluorescence Chemistry
- Organic Electronics and Photovoltaics
- Copper-based nanomaterials and applications
- Conducting polymers and applications
- Antibiotic Resistance in Bacteria
- Luminescence Properties of Advanced Materials
- Anodic Oxide Films and Nanostructures
- Layered Double Hydroxides Synthesis and Applications
- Quantum Dots Synthesis And Properties
- Surface Modification and Superhydrophobicity
- Gold and Silver Nanoparticles Synthesis and Applications
- TiO2 Photocatalysis and Solar Cells
- Electrospun Nanofibers in Biomedical Applications
- Organic Light-Emitting Diodes Research
- Biosensors and Analytical Detection
- Catalytic Processes in Materials Science
- Molecular Sensors and Ion Detection
- Dendrimers and Hyperbranched Polymers
Yonsei University
2012-2023
Seoul Institute
2020
Government of the Republic of Korea
2020
Kyung Hee University
2020
Novel multifunctional magnetic particles (MMPs) conjugated with photosensitizer and vancomycin were fabricated by surface modification of Fe3O4 particles. The capacities to target, capture inactivate pathogenic bacteria good biocompatibility suggest that the MMPs have great potentials as photodynamic inactivation agents for serious bacterial contamination.
Singlet oxygen is a toxic chemical but powerful oxidant, exploited in many and biological applications. However, the lifetime of singlet air under atmospheric conditions yet to be known. This has limited safe usage air, despite being strong antimicrobial agent with unique property relaxing breathable after serving its purpose. Here, we solve this long-standing problem by combining experimental theoretical research efforts; generate using photosensitizer at local source monitor time-dependent...
We report a novel photofunctional magnetic nanoparticle that is strategically designed and prepared by simple modification process. Photofunctionality provided the photosensitizer (PS) of [5,15-bis(phenyl)-10,20-bis(4-methoxycarbonylphenyl)porphyrin]platinum generates singlet oxygen in high quantum yield. The PS molecules are covalently bonded to surface nanoparticles. Microstructure photophysical properties nanoparticles investigated transmission electron microscopy, vibrating sample...
Reactive oxygen species (ROS) play an important role in cellular signaling as second messengers. However, studying the of ROS physiological redox has been hampered by technical difficulties controlling their generation within cells. Here, we utilize two inert components, a photosensitizer and light, to finely manipulate intracellular examine specific activating dendritic cells (DCs). Photoswitchable rapidly induced cytosolic mobilization Ca(2+), differential activation mitogen-activated...
Polymer–metal complex micelles (PMCMs) containing cisplatin (cis-dichlorodiammineplatinum(II), CDDP), an anticancer drug, were prepared by a coordination bond of CDDP to dendrimer phthalocyanine (DPc) and poly(ethylene glycol)-block-poly(L-aspartic acid) (PEG-PLAn; molecular weight PEG segment = 12 000 g mol−1; polymerization degrees aspartic acid n 68, 96). Transmission electron microscopy (TEM) laser light scattering (LLS) exhibited formation unimodal PMCM68 PMCM96 with average sizes 108...
The principle of photodynamic treatment (PDT) involves the administration photosensitizer (PS) at diseased tissues, followed by light irradiation to produce reactive oxygen species (ROS). In cells, a moderate increase in ROS plays an important role as signaling molecule promote cell proliferation, whereas severe causes damage. Previous studies have shown that low levels stimulate growth through PS drugs-treating PDT and nonthermal plasma treatment. However, these methods side effects which...
We have synthesized mesoporous TiO2 nanofibers loaded with Au nanoparticles (MTNF-Au) and fabricated single nanofiber-based devices. MTNF-Au devices exhibited surface plasmon enhanced photoconductance under visible light, whereas MTNF without did not. Moreover, Coulomb oscillations were observed at 4.2 K in devices, indicating that embedded played a role of islands. These results suggested the was ascribed to electron tunneling hot electrons generated by resonance.
The photocatalytic activity and photostability of CdS quantum dot (QD) can be remarkably enhanced by hybridization with Rh-substituted layered titanate nanosheet even at very low Rh substitution rate (<1%). Mesoporous CdS-Ti(5.2-x)/6 Rhx/2O2 nanohybrids are synthesized a self-assembly exfoliated Ti(5.2-x)/6 nanosheets QDs. partial Rh(3+)/Rh(4+) ions for Ti(4+) in is quite effective enhancing an electronic coupling between hybridized components via the formation interband 4d states. A crucial...
Background/Aims: Far-infrared (FIR) irradiation has been reported to exhibit various biological effects including improvement of cardiovascular function.However, its effect on the differentiation stem cells not studied.Using tonsil-derived mesenchymal (TMSC), we examined whether and how FIR affects adipogenic or osteogenic differentiation.Methods: TMSC were exposed (3-25 μm wavelength) for times (0, 30, 60 min), then was induced 14 days with respective commercially available medium.At end...
Water-dispersible graphitic hollow spheres were synthesized using a soft chemical route under hydrothermal conditions by glucose carbonization magnetite/silica-encapsulated core–shell sphere as template. Carbonization on the templates happens magnetite core is partially or completely eliminated depending reaction conditions. Therefore, nano-sized magnetite-core-encapsulated shells could be obtained. Also nitrogen-doped reaction. The and show wavelength dependent photoluminescence in 300–600...
Pheophorbide-a derivatives have been reported to be potential photosensitizers for photodynamic therapy (PDT). In this study, photophysics of pheophorbide-a (PaDs) were investigated along with their tumoricidal effect in vitro . PaDs modified by changing the coil length and/or making hydroxyl group (–OH) substitutions. Their photophysical properties studied steady-state and time-resolved spectroscopic methods. The was evaluated mouse breast cancer cell line (EMT6). Lifetime quantum yield...
Highly porous layered double hydroxide (LDH) and its calcined mixed metal oxide (MMO) were obtained by utilizing egg white (EW) as a biogenic template. The LDH was prepared through coprecipitation under the existence of beaten EW meringue, corresponding MMO calcining at 500 °C. According to X-ray diffraction, crystal structure well-developed with or without EW. In contrast, crystallinity analyses microscopic investigations clearly showed differences in particle orientation presence EW;...