The use of microwave plasma for sterilization is relatively new. advantages this method are the low temperature, time-savings and its nontoxic nature, in contrast to traditional methods such as heat gas treatment, radiation. This study investigated effects microwave-induced argon at atmospheric pressure on materials contaminated with various microorganisms, bacteria fungi. A low-cost reliable 2.45 GHz, waveguide-based applicator was designed generate pressure. system consisted a 1 kW...

Various types of commercialized wound dressings (e.g., films, foams, gels, and nanofiber meshes) have been clinically used as a physical barrier against bacterial invasion wound-healing materials. Although these can protect the wounded tissue from external environment, they cannot treat wounds that are already infected with bacteria. Herein, we report in situ H2O2-releasing hydrogels an active dressing antibacterial properties for treatment drug-resistant infection. In this study, H2O2 was...

Novel multifunctional magnetic particles (MMPs) conjugated with photosensitizer and vancomycin were fabricated by surface modification of Fe3O4 particles. The capacities to target, capture inactivate pathogenic bacteria good biocompatibility suggest that the MMPs have great potentials as photodynamic inactivation agents for serious bacterial contamination.

In this study, we report a new multifunctional nanoparticle with antioxidative and antibacterial activities in vitro. ZnO@GA nanoparticles were fabricated by coordinated covalent bonding of the antioxidant gallic acid (GA) on surface ZnO nanoparticles. This addition imparts both activity high affinity for bacterial cell membrane. Antioxidative at various concentrations evaluated using 2,2′-azino-bis(ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging method. Antibacterial against...

The retention of deoxynivalenol in noodles and bread made from naturally-contaminated flour was examined by a chemical analysis (HPLC) bioassays. level obtained both assays reduced boiling process, although only the bioassays showed it to have been baking. This study is first estimate exposure consumption final products wheat Japan.

Microbial biofilms are a functional matrix of microbial cells, enveloped in polysaccharides, enzymes and virulence factors secreted by them that can develop on indwelling medical devices biomaterials. Plasma sterilization has been widely studied recent years for biological applications. In this study, we evaluated the possibility removal anti-recovery microwave-induced argon plasma at atmospheric pressure. We observed all bacterial formatted Gram-negative Gram-positive bacteria removed less...

Photodynamic therapy (PDT) is a promising alternative to conventional cancer treatment methods. Nonetheless, improvement of in vivo light penetration and cell-targeting efficiency remain major challenges clinical photodynamic therapy. This study aimed develop multifunctional magnetic nanoparticles conjugated with photosensitizer (PS) cancer-targeting molecules via simple surface modification process for PDT. To selectively target cells PDT functionality, core (Fe₃O₄) were covalently bound...

In this study, we investigated the possible roles of (1,3)-(1,6)-β-d-glucan (β-glucan) and porous electrospun poly-lactide-co-glycolide (PLGA) membranes containing β-glucan for skin wound healing, especially their effect on adult human dermal fibroblast (aHDF) adipose tissue-derived stem cell (ADSC) activation, proliferation, migration, collagen gel contraction biological safety tests prepared membrane. This study demonstrated that PLGA have enhanced cellular responses, proliferation aHDFs...

To develop novel multifunctional magnetic nanoparticles (MNPs) with good properties, biocompatibility, and anticancer activities by photodynamic therapy (PDT), we synthesized cobalt ferrite (CoFe2O4) (CoFe2O4-HPs-FAs) functionalized coating them hematoporphyrin (HP) for introducing photo-functionality conjugating folic acid (FA) targeting cancer cells. We evaluated the of CoFe2O4-HPs-FAs checking resonance imaging (MRI) in vitro, its on FA receptor (FR)-positive FR-negative cell lines, Hela,...

We investigated the intramolecular charge transfer characteristics in S1 state of boron-dipyrromethene (BODIPY) derivatives with triphenylamine (TPA) substituents, depending on substituted position and number substituents. Based spectroscopic theoretical results, β-substitution TPA BODIPY hybridizes locally excited because strong coupling between highest occupied molecular orbitals moieties, consequently, β-substituted TPAs exhibit red-color fluorescence around 640 nm nonpolar moderately...

Crystalline metal-organic frameworks (MOFs) are extensively used in areas such as gas storage and small-molecule drug delivery. Although Cu-BTC (1, MOF-199, BTC: benzene-1,3,5-tricarboxylate) has versatile applications, its NO release characteristics not amenable to therapeutic usage. In this work, micro-sized was prepared solvothermally then processed by ball-milling prepare nano-sized (2). The properties of the micro- MOFs were morphology dependent. Control hydration degree delivery...

ABSTRACT Seawater used in mariculture has been suspected of being a potential source infection. In this study, the lethal effects low-amperage electric treatment on microorganisms were examined natural seawater and inoculated with Vibrio parahaemolyticus . both cases, bacteria including V completely eliminated 100 ms by 0.5-A, 12-V direct current. Electron microscopic investigation electrically treated revealed substantial structural damage at cellular level. conclusion, our results indicate...

Nanomedicine, which involves the use of magnetic nanoparticles such as Fe 3 O 4 , has provided novel technical solutions for cancer diagnosis and treatment. Most studies in nanomedicine have focused on with resonance imaging hyperthermia. However, to achieve optimum anticancer effects, it is important understand physicochemical properties their interactions biological entities. In this study, we synthesized particles various sizes conjugated them hematoporphyrin (HP) molecules by using a...

Recent reports using a breathing simulator system have suggested that mesh nebulizers provide more effective medication delivery than jet nebulizers. In this study, the performances of and were evaluated by comparing their aerosol drug efficiencies in mice. We compared four home nebulizers: two (PARI BOY SX with red blue nozzles), static nebulizer (NE-U22), vibrating (NE-SM1). After mice exposed to salbutamol aerosol, levels serum lung estimated enzyme linked immunoassay (ELISA). The...

During bone development, remodeling, and repair, morphogenetic proteins (BMPs) induce the differentiation of mesenchymal progenitor cells (MPCs) that enter into osteoblastic lineage, enhance recruitment MPCs osteogenic cells. The process migration is believed to be regulated, in part, by growth factors stored within matrix, which are released resorption. In this study, primary human stem (hMSCs) MC3T3-E1 osteoblasts were examined for chemotaxis response recombinant BMP-7 (rhBMP-7) produced...