A5031720395- Tuberculosis Research and Epidemiology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pneumonia and Respiratory Infections
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Inhalation and Respiratory Drug Delivery
- Asthma and respiratory diseases
- Tracheal and airway disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pulmonary Hypertension Research and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Sepsis Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Nosocomial Infections in ICU
- Pleural and Pulmonary Diseases
- Education, Achievement, and Giftedness
- Neonatal Respiratory Health Research
- Respiratory viral infections research
- Motivation and Self-Concept in Sports
- Antibiotic Resistance in Bacteria
- Cardiovascular Disease and Adiposity
- Cystic Fibrosis Research Advances
- Telomeres, Telomerase, and Senescence
- Biosimilars and Bioanalytical Methods
- Ultrasound in Clinical Applications
Dongguk University Ilsan Hospital
2012-2025
Pusan National University
2021
Inje University Busan Paik Hospital
2021
Chonnam National University Hospital
2021
St. Paul's Hospital
2019
University of British Columbia
2019
Dongguk University
2012-2013
National Institute of Allergy and Infectious Diseases
2010-2012
National Institutes of Health
2010-2012
Seoul National University
1995-2009
The Prevalence and Evolution of Anemia Associated with Tuberculosis (TB) may produce abnormalities in the peripheral blood, including anemia.However, evolution TB-associated anemia short-term combination anti-TB chemotherapy has not been well elucidated.The aim this study was to characterize by clarifying its prevalence, characteristics, evolution, through involving large numbers patients TB.The medical records adult TB diagnosed between June 2000 May 2001 were reviewed.Among 880 TB, 281...
ABSTRACT With a host of new antitubercular chemotherapeutics in development, methods to assess the activity these agents beyond mouse efficacy are needed prioritize combinations for clinical trials. Lesions Mycobacterium tuberculosis -infected rabbits hypoxic, with histopathologic features that closely resemble those human tuberculous lesions. Using [ 18 F]2-fluoro-deoxy- d -glucose ([ F]FDG) positron emission tomography–computed tomography (PET-CT) imaging, we studied dynamics infection...
<h3>Background</h3> Uncontrolled diabetes, unlike controlled is associated with an impaired immune response. However, little known about the impact of status diabetes control on clinical features and treatment outcomes in patients pulmonary TB (PTB). We conducted this study to evaluate whether influences manifestations responses PTB. <h3>Methods</h3> A multicentre prospective was performed between September 2012 2014. The were categorised into three groups according glycated haemoglobin...
Background/Objectives: The methacholine bronchial provocation test (MBPT) is a diagnostic frequently used to evaluate airway hyper-reactivity. MBPT essential for diagnosing asthma; however, it can be time-consuming and resource-intensive. This study aimed develop an artificial intelligence (AI) model predict the results using forced expiratory volume in one second (FEV1) bronchodilator measurements from spirometry. Methods: dataset of spirometry measurements, including Pre-...
Recent reports using a breathing simulator system have suggested that mesh nebulizers provide more effective medication delivery than jet nebulizers. In this study, the performances of and were evaluated by comparing their aerosol drug efficiencies in mice. We compared four home nebulizers: two (PARI BOY SX with red blue nozzles), static nebulizer (NE-U22), vibrating (NE-SM1). After mice exposed to salbutamol aerosol, levels serum lung estimated enzyme linked immunoassay (ELISA). The...
We evaluated whether the pathogens identified during acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) are associated with COPD medications used in 6 months before AE-COPD. collected medical records patients diagnosed AE-COPD at 28 hospitals between January 2008 and December 2019 retrospectively analyzed them. Microorganisms time were according to use inhaled corticosteroid (ICS) systemic steroid after adjusting for severity. 1177 available medication history. The mean...
Toxocariasis is one of the causes pulmonary eosinophilic infiltrate that increasing in Korea.This study was designed to identify prevalence toxocara seropositivity patients with unexplained patchy and evaluate associated factors.We evaluated 102 on chest computed tomography (CT) scan.As a control set, 116 subjects normal CT were also evaluated.History allergic disease, drug use, parasitic disease raw cow liver intake taken.Blood eosinophil count total IgE level measured.Specific serum IgG...
Local fat distribution patterns and their local or systemic effects have recently attracted significant attention. The aim of this study was to assess the impact thoracic adiposity on lung function in a population without respiratory diseases according sex.A total 455 subjects (282 males 173 females), who had undergone spirometry, chest abdominal computed tomography between June 2012 2016 at medical healthcare center, were included. Pericardial fat, intrathoracic subcutaneous both visceral...
Although respiratory tract infection is one of the most important factors triggering acute exacerbation chronic obstructive pulmonary disease (AE-COPD), limited data are available to suggest an epidemiologic pattern microbiology in South Korea.A multicenter observational study was conducted between January 2015 and December 2018 across 28 hospitals Korea. Adult patients with moderate-to-severe exacerbations COPD were eligible participate present study. The participants underwent all...
Mycobacterium tuberculosis (MTB) is a communicable disease and still remains threat to common health. Thus, early diagnosis treatment are required prevent the spread of infection. Despite recent advances in molecular diagnostic systems, commonly used MTB tools laboratory-based assays, such as mycobacterial culture, PCR, Xpert MTB/RIF. To address this limitation, point-of-care testing (POCT)-based technologies capable sensitive accurate detection even environments with limited sources needed....
Melioidosis is an infection of the Gram-negative bacterium Burkholderia pseudomallei. While it known as important cause sepsis or chronic abscess-forming disease in Southeast Asia and northern Australia, no case has yet been reported Korea. A 50-yr-old man visited our hospital for intermittent fever associated with dry cough sputum. Roentgenographic examination showed migrating pulmonary infiltration. Symptoms chest radiograph computed tomography (CT) image findings did not improve despite...
Patients with nursing home-acquired pneumonia (NHAP) should be treated as hospital-acquired (HAP) according to guidelines published in 2005. However, controversy still exists on whether the high mortality of NHAP results from multidrug resistant pathogens or underlying disease. We aimed outline differences and factors contributing between community-acquired (CAP) patients.We retrospectively evaluated patients aged 65 years older either CAP 2008 2014. healthcare-associated other than HAP were...
Abstract Background With the emergence of bronchiectasis as a common respiratory disease, epidemiological data have accumulated. However, prevalence and impact psychological comorbidities were not sufficiently evaluated. The present study examined depression its associated factors in patients with bronchiectasis. Methods This involved multicenter cohort recruited from 33 pulmonary specialist hospitals. baseline characteristics bronchiectasis-related at enrollment analyzed. Depressive...
A rapidly absorbed new novel oral dosage form for digoxin termed ‘digoxin dry elixir’ was developed by the spray-drying technique. Digoxin, dextrin and sodium lauryl sulphate were dissolved in a ethanol-water mixture (20:25 w/w) therefore spray-dried to elixir. According scanning electron micrographs, elixir is spherical shape with smooth surface. The geometric mean diameter of determined laser particle size analysis about 13 pm. appearance flow properties almost unchanged 10% ethanol...
Colistin, an important drug to treat carbapenem-resistant Acinetobacter baumannii (CRAB) infections, has a narrow therapeutic window with nephrotoxicity. This study was conducted determine the importance of colistin concentrations in predicting nephrotoxicity when treating CRAB pneumonia colistin.A prospective cohort performed one teaching hospital from May 2015 January 2018. Patients were treated intravenous methanesulfonate (CMS) at 2.5-5.0 mg/kg/day. On Days 3 and 4, plasma CMS determined...
Pneumonia is the cause of significant morbidity and mortality, despite advances in diagnosis antibacterial treatment. often misdiagnosed mistreated up until recently. Recent classification pneumonia consists community-acquired pneumonia, health care-associated hospital-acquired ventilator-associated pneumonia. The etiology, risk factors, treatment are different among them. This article briefly introduces new concepts ideas biomarkers, diagnosis, treatment, prognosis, prevention during past 2...
Latent tuberculosis infection (LTBI) is characterized by immune responses to Mycobacterium antigens without clinical symptoms or evidence of active tuberculosis. Effective LTBI management crucial for elimination, requiring accurate diagnosis and treatment. In South Korea, guidelines have been updated periodically, with the latest in 2024. This review discusses recent changes Korean guideline treatment adults.
Purpose. We aimed to determine the value of lung function measurement for predicting cardiovascular (CV) disease by evaluating association between FEV1 (%) and CV risk factors in general population. Materials Methods. This was a cross-sectional, retrospective study subjects above 18 years age who underwent health examinations. The relationship presence carotid plaque thickened IMT (≥0.8 mm) analyzed multiple logistic regression, PWV (%), serum uric acid linear regression. Various were...
The twin method assumes that the trait under study is similar in twins and singletons so results from samples can be generalized to singleton population. purpose of present was compare self-concept matched parental level education. 6 cluster scales Piers-Harris Children's Self-Concept Scale (P-H) were administered 630 children 635 aged 7 12 years. Model-fitting analyses yielded two conclusions. First, generally between first- second-born monozygotic dizygotic across P-H. Second, consistently...
Abstract The twin method assumes that the trait under study is similar in twins and singletons so results from samples can be generalized to singleton population. purpose of present was compare self-concept matched parental level education. 6 cluster scales Piers-Harris Children's Self-Concept Scale (P-H) were administered 630 children 635 aged 7 12 years. Model-fitting analyses yielded two conclusions. First, generally between first- second-born monozygotic dizygotic across P-H. Second,...