A5020970115- Urological Disorders and Treatments
- Pediatric Urology and Nephrology Studies
- Urinary Bladder and Prostate Research
- Spinal Dysraphism and Malformations
- Child and Adolescent Health
- Urinary Tract Infections Management
- Neonatal Respiratory Health Research
- Respiratory viral infections research
- Urinary and Genital Oncology Studies
- Artificial Intelligence in Healthcare and Education
- Ethics in Clinical Research
- Pediatric health and respiratory diseases
- Non-Invasive Vital Sign Monitoring
- Bladder and Urothelial Cancer Treatments
- Sarcoma Diagnosis and Treatment
- Urologic and reproductive health conditions
- Ethics in medical practice
- Nanocluster Synthesis and Applications
- Hernia repair and management
- Testicular diseases and treatments
- Congenital Diaphragmatic Hernia Studies
- Sexual Differentiation and Disorders
- Kidney Stones and Urolithiasis Treatments
- Gold and Silver Nanoparticles Synthesis and Applications
- Sperm and Testicular Function
Children's Hospital of Fudan University
2014-2024
Shanghai Children's Hospital
2012-2019
South China University of Technology
2016-2018
Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in extremely preterm neonates. The outcome and clinical burden vary dramatically according to severity. Although some prediction tools for BPD exist, they seldom pay attention severity are based on populations developed countries. This study aimed develop machine learning models selected factors Chinese population.
Au nanoparticles (NPs) have important applications in bioimaging, clinical diagnosis and even therapy due to its water-solubility, easy modification drug-loaded capability, however, aggregation of NPs normal saline serum greatly limits applications. In this work, highly stabilized core-satellite nanoassemblies (CSAuNAs) were constructed by a hierarchical DNA-directed self-assembly strategy, which satellite number could be effectively tuned through varying the ratios core-AuNPs-ssDNA...
Pt-based catalysts with novel structure have attracted great attention due to their outstanding performance. In this work, H2PtCl6 was used as both precursor and etching agent realize the shape-controlled synthesis of Pt-modified Au@Ag nanorods (NRs). During synthesis, as-prepared Ag shell played a crucial role in protecting Au NRs from being etched away by PtCl62– leading an unusual growth mode Pt component. The site-specified and/or depended on concentration H2PtCl6, where high-yield...
About 50% N-acetylation-thiolated chitosan possessing good water solubility was modified from commercial low-molecular-weight chitosan. Chitosan performed obvious target toward renal tubular epithelial cells, and bivalent cobalt ions improved the fibrosis inflammation significantly. There were many complexation sites on after being with sulfydryl. So sulfydryl played a role of connecting bridge between ions. Then, this (NTCC) nanocomplex designed. The showed excellent stability under normal...
Bladder compliance assessment is crucial for diagnosing bladder functional disorders, with urodynamic study (UDS) being the principal evaluation method. However, application of UDS intricate and time-consuming in children. So it'S necessary to develop an efficient screen approach before UDS. In this study, We constructed a dataset based on designed 1D-CNN model optimize train network. Then applied trained obtained solely through proposed perfusion experiment. Our outperformed other...
Objective To report the application of laparoscopic single‐incision triangulated umbilical surgery (SITUS) pyeloplasty in children with ureteropelvic junction obstruction (UPJO) and compare its feasibility efficacy traditional three‐hole pyeloplasty. Methods Data from UPJO who underwent SITUS between July 2018 August 2021 were included this retrospective study patients treated chosen for comparison. Thirty‐two group 72 reviewed. The clinical characteristics, complications, follow‐up results...
This study aimed to review and compare the characteristics treatment outcomes of cryptorchid testicular torsion in pre- postpubertal children. We reviewed clinical data 22 patients with complicated by cryptorchidism who were treated between January 2010 December 2019. Patients categorized into prepubertal (1 month 9 years; n = 12) groups (10–16 10). The age at presentation, presentations, physical examination, operation assessed. common presentations both inguinal pain a tender mass. group...
Abstract Background Respiratory infections are one of three leading causes childhood mortality, and worldwide increase recent plateau in asthma has been reported. However, data on trends respiratory diseases over long period time is limited. This study aimed to determine the disease outpatient visits (ROVs) diagnoses (RODs) largest children’s teaching hospitals China between 2009 2018. Methods A retrospective based routine administrative was designed implemented according RECORD statement....
Lower urinary tract symptoms (LUTs) are common in young boys with posterior urethral valves (PUVs). It is crucial to investigate the characteristics of PUV patients and without LUTs after valve ablation.Between January 2017 December 2019, visited Children's Hospital, Fudan University for following up were enrolled. Medical records information from patients' urodynamic studies (UDS) reviewed.A total 54 enrolled divided into symptomatic group (28 cases) non-symptomatic (26 according daytime...
Fetal repair of myelomeningocele (MMC) has been proven to be beneficial for the central nervous system development; however, effect fetal MMC on bladder function remains controversial. The objective present study was establish an early timepoint in utero using a rat model, and investigate changes development subsequent that intervention. Sprague Dawley rats were divided into MMC, control groups. fetus models created by treating pregnant with all‑trans retinoic acid. defect then repaired at...
In this paper, we focus on the Bronchopulmonary Dysplasia (BPD) prediction task, which aims to identify BPD in premature infants based given medical images. The existing methods for task sometimes learn spurious relations (confounders) between image and label while ignore causal features due limited size of dataset, largely influences interpretability robustness model. To address challenge problem, propose an interpretable method prediction, can eliminate irrelevant capture features. We term...
The development of the pediatric care system is uneven in China. Limited research has been conducted on Shanghai, which a well-developed region China, National Children's Medical Centers are located.In November 2021, under commission Shanghai Center for Quality Control, city-wide questionnaire designed to examine provision medical services children 2020 was at 86 hospitals providing care. overall characteristics and disparities between general children's suggestions future developments were...
Implementing ethics is crucial to prevent harm and promote widespread benefits in social experiments based on medical artificial intelligence (MAI). However, insufficient information available concerning this within the paediatric healthcare sector. We aimed conduct a comparative survey among paediatricians, nurses health technicians regarding implementation knowledge of attitude towards MAI at children's hospitals Shanghai. A cross-sectional electronic questionnaire was administered from 1...
Congenital anomalies of the kidneys and urinary tracts (CAKUT) represent most prevalent cause for renal failure in children. The RNA epigenetic modification N6-methyladenosine (m6A) methylation modulates gene expression function post-transcriptionally, which has recently been revealed to be critical organ development. However, it is uncertain whether m6A plays a role pathogenesis CAKUT. Thus, we aimed explore pattern CAKUT.Using m6A-mRNA epitranscriptomic microarray, investigated methylomic...
The deformation of congenital obstruction the anterior urethra is rare in male infants. urethral valve (AUV) and diverticulum are not common causes distal obstruction, which may be significant but difficult to diagnose time. We describe a premature infant who was diagnosed with AUV as part presented massive urinary ascites without hydroureters hydronephrosis. After indwelling abdominal tube catheterization, infant’s were resolved, while had successful treatment by Holmium laser. suggest that...
Background: Urine leakage of collecting system occurs as a result lower urinary tract obstructions (LUTOs) like posterior urethral valves (PUVs). We report the short-term prognosis PUV in infants with rupture by retrospective review clinical data and patient follow-up. Methods: Medical records from 2010 to 2018 our center were reviewed, rupture, well current follow-up, analyzed. Results: A total 10 met criteria an admission age 7 days 15.5 months. There are 6 cases perinephric urinoma, 2...
Abstract Background: Respiratory infections are one of three leading causes childhood mortality, and worldwide increase recent plateau in asthma has been reported. However, data on trends respiratory diseases over long period time is limited. This study aimed to determine the disease outpatient visits (ROVs) diagnoses (RODs) largest children’s teaching hospitals China between 2009 2018. Methods: A retrospective based routine administrative was designed implemented according RECORD statement....