A5065420021- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Cancer Immunotherapy and Biomarkers
- Renal cell carcinoma treatment
- COVID-19 and healthcare impacts
- Cancer Treatment and Pharmacology
- Advanced Breast Cancer Therapies
- Renal and related cancers
- Cancer Diagnosis and Treatment
- Breast Lesions and Carcinomas
- Tumors and Oncological Cases
- Family Support in Illness
- Cancer survivorship and care
- Head and Neck Cancer Studies
- Immunotherapy and Immune Responses
- Orthopedic Surgery and Rehabilitation
- Reconstructive Surgery and Microvascular Techniques
- Breast Implant and Reconstruction
- Chemotherapy-induced organ toxicity mitigation
- Fungal Infections and Studies
- Viral-associated cancers and disorders
- Respiratory Support and Mechanisms
- Immune cells in cancer
- Intimate Partner and Family Violence
- Attachment and Relationship Dynamics
University of Pavia
2008-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2009-2023
Policlinico San Matteo Fondazione
1994-2023
University Hospital Foundation
2022
Fondazione Salvatore Maugeri
2011-2012
The interactions between aromatase inhibitors (AI) in breast cancer (BC) and gut microbiota (GM) have not been completely established yet. aim of the study is to evaluate bio-diversity GM relationship GM, inflammation tumor-infiltrating lymphocytes (TILs) postmenopausal women with BC during adjuvant AI treatment compared disease relapse or after one year therapy (“endocrine-resistant”). We conducted a monocenter observational case-control study. Eighty-four (8 cases, 76 controls) were...
Patients with renal cell carcinoma (RCC) may exhibit impairment as a more or less direct consequence of their primary disease. Renal become severe complication and alter the normal pharmacokinetic pharmacodynamic behavior treatment drugs, thus increasing risk side effects. We will discuss cases two advanced RCC patients end-stage submitted to dialysis who were treated sorafenib tosylate in our center. Our experience confirms scarce literature data available so far that indicate can be used...
Renal cell carcinoma (RCC) accounts for the 3% of all solid tumors. Despite continuous improvement in therapy regimen, less has been achieved terms enabling an earlier diagnosis: neoplasia usually reveals its presence at advanced stage, obviously affecting prognosis. The most frequent sites secondary disease are shown to be lungs (50-60%), bone (30-40%), liver (30-40%) and brain (5%); while head neck district seems account than 1% patients with primary kidney lesion. We report here case a...
Tumour markers have no established role in the monitoring of course metastatic breast cancer during antineoplastic therapy, yet antigen 15.3 (CA15.3) and carcinoembryonic (CEA) are commonly used clinical practice to aid early detection progression disease (PD). In our multicentre, prospective, real-life study, we enrolled 142 consecutive patients with advanced receiving endocrine therapy combination a CDK4/6 inhibitor from January 2017 October 2020; 75 had PD at time database closure. We...
Abstract Background Metastatic breast cancer (MBC) is an incurable disease and its treatment focuses on prolonging patients’ (pts) overall survival (OS) improving their quality of life. Eribulin a microtubule inhibitor that increases OS in pre-treated MBC pts. The most common adverse events (AEs) are asthenia, neutropenia peripheral neuropathy (PN). Methods PAINTER single arm, phase IV study, aimed at evaluating the tolerability eribulin Secondary objectives were description efficacy safety,...
In the last decade, international literature has widely investigated what is successfully associated with decision making in context of breast cancer and genetic high risk. What hinders decision-making patients BRCA1/2 carriers still not clear. We are reporting case a young woman, 45 years old, affected by BRCA 1 pathogenetic mutation previous cancer. We called her Pamela. She showed to physicians difficulties decisions about preventive interventions hereditary (mastectomy, oophorectomy)....
We present our commentary about the case of a 48-year-old woman diagnosed with early breast cancer, already presented as publication.A candidate for mastectomy, she refused immediate reconstruction.She was referred to psycho-oncologist further evaluation and support.Psychological sessions helped reveal history intimate partner violence clarify reason her refusal undergo reconstruction other uncommon behavior oncological treatment disease paths.Our experience highlights importance...
Abstract Purpose With the emergence of coronavirus disease 2019 (COVID-19), Oncologists have had to face challenge continuing active treatments without compromising safety our patients and healthcare personnel. Methods From February 24th, we reorganized Oncology Unit with introduction a double-step triage strategy for cancer under treatment in order identify at risk from COVID-19 avoid their admission outpatient clinic inpatient ward. Results 24 April 7 2020, performed 819 phone calls,...
Abstract BACKGROUND Metastatic breast cancer (MBC) is an incurable disease and its treatment focuses on prolonging patients (pts) overall survival (OS) improving their quality of life. eribulin a microtubule inhibitor that increases OS in pre-treated MBC pts. Its common adverse events (AEs) are asthenia, neutropenia peripheral neuropathy (PN). METHODS The PAINTER single arm, phase IV study, aimed at surveying tolerability Secondary objectives were to explore incidence severity PN,...
With the emergence of COVID-19, Oncologists have had to face up challenge continuing active treatments without compromising patients and healthcare personnel's safety.We introduced a double-step triage strategy (by phone on site) for cancer in order identify at risk COVID-19 avoid their admission our Oncology Unit.From February 24 th April 7 2020, we performed 819 calls, leading authorization 788 accesses (312 patients) outpatient clinic.26 were kept home, 23 managed with